Find a Hotel in Downtown Rochester

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Top hotels in Downtown Rochester

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

3.5 out of 5
10 East Center Street Rochester MN
Fully refundableReserve now, pay when you stay
$171 nightly
The price is $197 total per night from Feb 6 to Feb 7
$197 total
Feb 6 - Feb 7
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
I wish breakfast was included, we have breakfast you day over the space designated for and couple things was very cold like coffee etc

Reviewed on Jan 10, 2026

Opens in a new windowHilton Rochester Mayo Clinic Area
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

3 out of 5
15 1st Street Southeast Rochester MN
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $185 total per night from Jan 23 to Jan 24
$185 total
Jan 23 - Jan 24
Total with taxes and fees
This apartment features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. There's a hot tub ...
Very spacious, quiet, accessible via a 10 min walk to Mayo campus all indoors via well-marked skyway and subway. And connected to a City parking deck ($18/day) and many amenities like the Hilton Hotel, The Galleria, good views and more. Second bathroom is a nice touch and the full kitchen w d/w is ...

Reviewed on Dec 27, 2025

Opens in a new windowBroadway Plaza, Trademark Collection by Wyndham
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $150 total per night from Jan 31 to Feb 1
$150 total
Jan 31 - Feb 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Was supposed to have food available and there wasn't due to not having a cook. Nobody said anything at check-in, wasn't listed on their website. Cost extra to have food delivered, which we were trying to avoid.

Reviewed on Jan 12, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$90 nightly
The price is $104 total per night from Jan 24 to Jan 25
$104 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Need to change up the beding. Not the best. Comforter to hold.

Reviewed on Jan 14, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 out of 5
123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $122 total per night from Jan 22 to Jan 23
$122 total
Jan 22 - Jan 23
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
Very convenient to mayo and dt area! Great value!

Reviewed on Jan 14, 2026

Opens in a new windowBrentwood Inn & Suites
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

3 out of 5
225 S Broadway Rochester MN
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $123 total per night from Jan 30 to Jan 31
$123 total
Jan 30 - Jan 31
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and perks like free WiFi. There's a hot tub on site, and laundry facilities ...
Very friendly close to everything we needed

Reviewed on Jan 14, 2026

Opens in a new windowHilton Garden Inn Rochester Downtown, MN
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Jan 22 to Jan 23
$146 total
Jan 22 - Jan 23
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
The employees were very nice and polite.

Reviewed on Jan 14, 2026

Opens in a new windowKahler Grand Hotel
Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic

3.5 out of 5
101 1st Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $165 total per night from Jan 24 to Jan 25
$165 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, ...
Great staff, hotel restaurant was very good. Valet for our vehicle was very helpful. Very convenient to Mayo.

Reviewed on Dec 15, 2025

Opens in a new windowMarriott Rochester Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Jan 24 to Jan 25
$151 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
It is great but very noisy next to active construction. Very hard to rest in between appointments. BRING EAR PLUGS.

Reviewed on Jan 15, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Downtown Rochester Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Downtown Rochester area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Downtown Rochester to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Downtown Rochester are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Downtown Rochester hotel reviews by fellow wanderers

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

5 out of 5
Posted 5 days ago
Travelocity Verified Review
"It is great but very noisy next to active construction. Very hard to rest in between appointments. BRING EAR PLUGS. "
A verified traveler stayed at Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area

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