Explore top 2025 5 Star Hotels in Brookline

Start date: Check-in selected.
To Date
End date: Check-out

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Top Brookline 5 Star hotels

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

5 out of 5
450 Summer Street Boston MA
Fully refundableReserve now, pay when you stay
$204 nightly
The price is $238 total per night from Dec 19 to Dec 20
$238 total
Dec 19 - Dec 20
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 2 bars/lounges and get perks like ...
9/10 Wonderful! (4,196 reviews)
Microwave in the room

Reviewed on Nov 11, 2025

Opens in a new windowOmni Boston Hotel at the Seaport
Encore Boston Harbor

Encore Boston Harbor

5 out of 5
1 Broadway Everett MA
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $279 total per night from Nov 25 to Nov 26
$279 total
Nov 25 - Nov 26
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and a nightclub. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
9.6/10 Exceptional! (3,371 reviews)
Room was beautiful ,what a view , they gave us a upgrade to a suite 2nd time there food is excellant

Reviewed on Nov 12, 2025

Opens in a new windowEncore Boston Harbor
The Langham, Boston

The Langham, Boston

5 out of 5
250 Franklin St Boston MA
Fully refundableReserve now, pay when you stay
$355 nightly
The price is $413 total per night from Nov 24 to Nov 25
$413 total
Nov 24 - Nov 25
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and babysitting. ...
9.6/10 Exceptional! (1,001 reviews)
I stayed more than once in the Langham , the whole staff is awesome especially the reception guys and ladies, Ella and Geremy made the effort for a pleasant stay , Wanda from the housekeeping was so caring and helpful , the whole team made me always feel at home . I surely will be there whenever ...

Reviewed on Nov 13, 2025

Opens in a new windowThe Langham, Boston
The Newbury Boston

The Newbury Boston

5 out of 5
15 Arlington St Boston MA
Fully refundableReserve now, pay when you stay
$353 nightly
The price is $411 total per night from Dec 15 to Dec 16
$411 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. If you want ...
9.2/10 Wonderful! (536 reviews)
Excellent hotel.

Reviewed on Nov 7, 2025

Opens in a new windowThe Newbury Boston
Four Seasons Hotel Boston

Four Seasons Hotel Boston

5 out of 5
200 Boylston St Boston MA
$750 nightly
The price is $873 total per night from Nov 25 to Nov 26
$873 total
Nov 25 - Nov 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
9.2/10 Wonderful! (447 reviews)
The Vault is so genius. The staff is beyond compare, intelligent, professional to the highest standard and very thoughtful.

Reviewed on Sep 24, 2025

Opens in a new windowFour Seasons Hotel Boston
InterContinental Boston by IHG

InterContinental Boston by IHG

5 out of 5
510 Atlantic Ave Boston MA
Fully refundable
$254 nightly
The price is $296 total per night from Dec 18 to Dec 19
$296 total
Dec 18 - Dec 19
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.2/10 Wonderful! (1,007 reviews)
Staff was so helpful. Location amazing. Valet parking easy.

Reviewed on Nov 17, 2025

Opens in a new windowInterContinental Boston by IHG
Boston Harbor Hotel

Boston Harbor Hotel

5 out of 5
70 Rowes Wharf Boston MA
Fully refundableReserve now, pay when you stay
$333 nightly
The price is $387 total per night from Nov 25 to Nov 26
$387 total
Nov 25 - Nov 26
Total with taxes and fees
A marina, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly dining, ...
9.6/10 Exceptional! (1,003 reviews)
Everything was great.

Reviewed on Nov 14, 2025

Opens in a new windowBoston Harbor Hotel
Mandarin Oriental, Boston

Mandarin Oriental, Boston

5 out of 5
776 Boylston St Boston MA
Fully refundableReserve now, pay when you stay
$381 nightly
The price is $443 total per night from Dec 3 to Dec 4
$443 total
Dec 3 - Dec 4
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, express check-in, ...
9.2/10 Wonderful! (376 reviews)
They should stop the issues with things breaking in the men’s spa

Reviewed on Oct 27, 2025

Opens in a new windowMandarin Oriental, Boston
Four Seasons Hotel One Dalton Street, Boston

Four Seasons Hotel One Dalton Street, Boston

5 out of 5
One Dalton Street Boston MA
Fully refundableReserve now, pay when you stay
$555 nightly
The price is $646 total per night from Dec 18 to Dec 19
$646 total
Dec 18 - Dec 19
Total with taxes and fees
A full-service spa, 3 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.6/10 Exceptional! (359 reviews)
wonderful stay ...Love the staff ...doormen, valet and front desk all super friendly and helpful :)

Reviewed on Oct 13, 2025

Opens in a new windowFour Seasons Hotel One Dalton Street, Boston
The Liberty, a Marriott Luxury Collection Hotel, Boston

The Liberty, a Marriott Luxury Collection Hotel, Boston

5 out of 5
215 Charles St Boston MA
Fully refundableReserve now, pay when you stay
$234 nightly
The price is $272 total per night from Nov 23 to Nov 24
$272 total
Nov 23 - Nov 24
Total with taxes and fees
A nightclub, 2 restaurants, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.6/10 Excellent! (1,002 reviews)
THE DINNER MENU WAS SOUP AND IT WAS PERFECT, THE STAFF WERE VERY FRIENDLY AND MADE US FEEL AT HOME...THEY WERE AMAZING!

Reviewed on Nov 13, 2025

Opens in a new windowThe Liberty, a Marriott Luxury Collection Hotel, Boston
Don't see what you're looking for?
See all available properties in Brookline
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Brookline Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Brookline to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Brookline 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Brookline before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Brookline hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity