Explore top 2026 5 Star Hotels in Brookline

Name: Mandarin Oriental, Boston
Price range: $769 total

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top Brookline 5 Star hotels

Omni Boston Hotel at the Seaport

450 Summer Street Boston MA

Fully refundableReserve now, pay when you stay

$250 nightly

$291 total

Nov 20 - Nov 21

Total with taxes and fees

A full-service spa, 4 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 2 bars/lounges and get perks like ...

Encore Boston Harbor

1 Broadway Everett MA

Fully refundableReserve now, pay when you stay

$279 nightly

$312 total

Nov 11 - Nov 12

Total with taxes and fees

This luxury hotel features a casino, a full-service spa, and a nightclub. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...

9.6/10 Exceptional! (4,278 reviews)

"I stayed at the property for 3 days this week while the labor union was protesting out front and literally had a marching band that kept me up all night. I called guest services and they offered earplugs. They could not move my room. I literally got no sleep for a business trip. The protesting disturbs ..."

Reviewed on Oct 20, 2026

The Langham, Boston

250 Franklin St Boston MA

Fully refundableReserve now, pay when you stay

$489 nightly

$569 total

Nov 20 - Nov 21

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and babysitting. ...

9.8/10 Exceptional! (1,003 reviews)

"Every thing was fantastic"

Reviewed on Oct 19, 2026

Four Seasons Hotel Boston

200 Boylston St Boston MA

$825 nightly

$961 total

Nov 1 - Nov 2

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

9.4/10 Exceptional! (491 reviews)

"For the most high end hotel in Boston, lacked updated amenities that other newer hotels have. Rooms were severely dated."

Reviewed on Oct 20, 2026

The Charles Hotel

One Bennett Street Cambridge MA

Fully refundableReserve now, pay when you stay

$347 nightly

$403 total

Nov 13 - Nov 14

Total with taxes and fees

A full-service spa, 3 restaurants, and a 24-hour gym are all featured at this luxury hotel. Traveling on business? Take advantage of the 24-hour business center, ...

9.4/10 Exceptional! (1,000 reviews)

"Friendly staff at check-in, a well-stocked room off the lobby filled with complimentary candies (and to-go bags!), and charmingly-designed rooms made this a lovely stay. The location off Harvard Square made getting to and from the hotel so easy."

Reviewed on Oct 21, 2026

Boston Harbor Hotel

70 Rowes Wharf Boston MA

Fully refundableReserve now, pay when you stay

$644 nightly

$750 total

Nov 20 - Nov 21

Total with taxes and fees

A marina, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly dining, ...

The Newbury Boston

One Newbury Street Boston MA

$719 nightly

$837 total

Nov 1 - Nov 2

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the picnic area and in-room childcare. If you want to take your pet ...

9.4/10 Exceptional! (744 reviews)

"Whatever you do… do NOT allow them to put you in a room anywhere near (including above) the pool (especially #241). Unless you want to hear music pumped into your room all night and get zero sleep. Meditation music with deep low frequency droning passes through structures, walls/floors. A form of ..."

Reviewed on Oct 20, 2026

InterContinental Boston by IHG

510 Atlantic Ave Boston MA

Fully refundable

$342 nightly

$398 total

Nov 1 - Nov 2

Total with taxes and fees

A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.4/10 Exceptional! (1,188 reviews)

"Such a lovely experience for the family"

Reviewed on Oct 21, 2026

Four Seasons Hotel One Dalton Street, Boston

One Dalton Street Boston MA

Fully refundableReserve now, pay when you stay

$645 nightly

$751 total

Nov 1 - Nov 2

Total with taxes and fees

A full-service spa, 3 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.6/10 Exceptional! (456 reviews)

"We always have a fantastic stay at 1 Dalton Street. This time was no different, wonderful stay."

Reviewed on Oct 20, 2026

Mandarin Oriental, Boston

776 Boylston St Boston MA

Fully refundableReserve now, pay when you stay

$660 nightly

$769 total

Nov 8 - Nov 9

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Families will appreciate the onsite laundry facilities and babysitting. ...

Don't see what you're looking for?

See all available properties in Brookline

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Five Star Hotels in Brookline

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Brookline to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Brookline 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Brookline before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.