Explore top 2026 5 Star Hotels in Medford

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Top Medford 5 Star hotels

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

5 out of 5
450 Summer Street Boston MA
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $249 total per night from May 29 to May 30
$249 total
May 29 - May 30
Total with taxes and fees
A full-service spa, 4 restaurants, and an outdoor pool are all featured at this luxury hotel. Relax with a drink at one of the 2 bars/lounges and get perks like ...
9.2/10 Wonderful! (4,650 reviews)
"It was SO expensive."

Reviewed on May 18, 2026

Opens in a new windowOmni Boston Hotel at the Seaport
Encore Boston Harbor

Encore Boston Harbor

5 out of 5
1 Broadway Everett MA
Fully refundableReserve now, pay when you stay
$308 nightly
The price is $344 total per night from May 21 to May 22
$344 total
May 21 - May 22
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and a nightclub. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, ...
9.6/10 Exceptional! (3,765 reviews)
"Great hotel in Boston."

Reviewed on May 18, 2026

Opens in a new windowEncore Boston Harbor
The Langham, Boston

The Langham, Boston

5 out of 5
250 Franklin St Boston MA
Fully refundableReserve now, pay when you stay
$515 nightly
The price is $600 total per night from Jun 5 to Jun 6
$600 total
Jun 5 - Jun 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Families will appreciate the onsite laundry facilities, kid-friendly dining, and babysitting. ...
9.8/10 Exceptional! (1,004 reviews)
"Good but needed more choice in the langham executive lounge"

Reviewed on May 18, 2026

Opens in a new windowThe Langham, Boston
InterContinental Boston by IHG

InterContinental Boston by IHG

5 out of 5
510 Atlantic Ave Boston MA
$302 nightly
The price is $352 total per night from May 25 to May 26
$352 total
May 25 - May 26
Total with taxes and fees
A full-service spa, 2 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...
9.4/10 Exceptional! (1,117 reviews)
"OK, this hotel is simply incredibly well managed. Everything about it was excellent and while I have stayed here before, my most recent experience far surpassed my initial intro. I absolutely loved it. The lobby, the scent, the cleanliness, the room, and OMG the Byredo products - WOW! I will be back. ..."

Reviewed on May 18, 2026

Opens in a new windowInterContinental Boston by IHG
The Newbury Boston

The Newbury Boston

5 out of 5
15 Arlington St Boston MA
Fully refundableReserve now, pay when you stay
$584 nightly
The price is $680 total per night from May 25 to May 26
$680 total
May 25 - May 26
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Families will appreciate the onsite laundry facilities and in-room childcare. If you want ...
9.4/10 Exceptional! (644 reviews)
"El hotel es una belleza y tiene ubicación inigualable. Pero creo que esta vez estaban bajos de personal y con alta demanda por las graduaciones. No había lugar en los restaurantes para los huéspedes y cuando pedía que me hicieran las reservas no me resolvían incluso el viernes me dijeron que me iban ..."

Reviewed on May 18, 2026

Opens in a new windowThe Newbury Boston
Four Seasons Hotel Boston

Four Seasons Hotel Boston

5 out of 5
200 Boylston St Boston MA
$820 nightly
The price is $955 total per night from May 21 to May 22
$955 total
May 21 - May 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
9.4/10 Exceptional! (472 reviews)
"Great service great location"

Reviewed on May 7, 2026

Opens in a new windowFour Seasons Hotel Boston
Boston Harbor Hotel

Boston Harbor Hotel

5 out of 5
70 Rowes Wharf Boston MA
Fully refundableReserve now, pay when you stay
$623 nightly
The price is $725 total per night from May 25 to May 26
$725 total
May 25 - May 26
Total with taxes and fees
A marina, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly dining, ...
9.8/10 Exceptional! (1,001 reviews)
"clean and great staff"

Reviewed on May 8, 2026

Opens in a new windowBoston Harbor Hotel
Four Seasons Hotel One Dalton Street, Boston

Four Seasons Hotel One Dalton Street, Boston

5 out of 5
One Dalton Street Boston MA
Fully refundableReserve now, pay when you stay
$730 nightly
The price is $850 total per night from May 29 to May 30
$850 total
May 29 - May 30
Total with taxes and fees
A full-service spa, 3 restaurants, and an indoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
9.6/10 Exceptional! (409 reviews)
"About as nice as it gets in Boston."

Reviewed on May 2, 2026

Opens in a new windowFour Seasons Hotel One Dalton Street, Boston
The Liberty, a Marriott Luxury Collection Hotel, Boston

The Liberty, a Marriott Luxury Collection Hotel, Boston

5 out of 5
215 Charles St Boston MA
Fully refundableReserve now, pay when you stay
$300 nightly
The price is $349 total per night from May 25 to May 26
$349 total
May 25 - May 26
Total with taxes and fees
A nightclub, 2 restaurants, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.8/10 Excellent! (1,001 reviews)
"Fantastic stay! What a Fun hotel with a lively lobby! Music good drinks, fun people. I loved it!"

Reviewed on May 16, 2026

Opens in a new windowThe Liberty, a Marriott Luxury Collection Hotel, Boston
Mandarin Oriental, Boston

Mandarin Oriental, Boston

5 out of 5
776 Boylston St Boston MA
Fully refundableReserve now, pay when you stay
$676 nightly
The price is $787 total per night from May 24 to May 25
$787 total
May 24 - May 25
Total with taxes and fees
A full-service spa, a gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, express check-in, ...
9.4/10 Exceptional! (422 reviews)
"Great hotel great staff great location"

Reviewed on May 9, 2026

Opens in a new windowMandarin Oriental, Boston
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Medford Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Medford to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Medford 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Medford before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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