Book Hotels in Southeast Minnesota, MN
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Top Southeast Minnesota hotels

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Nov 27 to Nov 28
$128 total
Nov 27 - Nov 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Stay was as usual. The property has been sold to new owners, resulting in some changes. 1) They now charge for parking- $20 per night. It didn’t get charged earlier. But they now restrict access to parking via room keys so hopefully vehicles are safer. 2) Saw an upgrade in breakfast- it was visibly ..."
Reviewed on Nov 9, 2026

Treasure Island Resort & Casino
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $103 total per night from Nov 15 to Nov 16
$103 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
"Pools was closed for the kids the only reason we were there and they did not tell me when booking"
Reviewed on Nov 9, 2026

Brentwood Inn & Suites
123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $138 total per night from Nov 12 to Nov 13
$138 total
Nov 12 - Nov 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
"Good for the price, nice location to Mayo Clinic"
Reviewed on Nov 8, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Nov 14 to Nov 15
$131 total
Nov 14 - Nov 15
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"Needs renovation"
Reviewed on Nov 9, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $171 total per night from Dec 11 to Dec 12
$171 total
Dec 11 - Dec 12
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Staff was very helpful; handicapped bathroom was perfect for Mom's wheelchair. Being able to walk across the street to Mayo was a godsend. Will stay there again when she has her 6 month checkup!"
Reviewed on Nov 10, 2026

Express Suites Riverport Inn & Suites
900 Bruski Dr Winona MN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Dec 6 to Dec 7
$123 total
Dec 6 - Dec 7
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"We have stayed here before and had a great experience. This time our room had food under the furniture, the room had a horrible smell, none of the vending or ice machines were working, nor was the juice machine at breakfast and the waffle mix was sour."
Reviewed on Nov 9, 2026

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $158 total per night from Nov 22 to Nov 23
$158 total
Nov 22 - Nov 23
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Lots of construction going on but everything we needed including access to the Mayo Clinic was with walking distance. Room clean and comfortable, although a little small. No complaints. Served our purpose well."
Reviewed on Nov 9, 2026

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $86 total per night from Dec 10 to Dec 11
$86 total
Dec 10 - Dec 11
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
$73 nightly
The price is $84 total per night from Dec 6 to Dec 7
$84 total
Dec 6 - Dec 7
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Minnesota hotels

Red Carpet Inn Rochester
2214 South Broadway Rochester MN
$63 nightly
The price is $73 total per night from Nov 11 to Nov 12
$73 total
Nov 11 - Nov 12
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southeast Minnesota with star-rating
Check Southeast Minnesota Hotels by Star Rating

4 Star Hotels
7 properties
Recent Southeast Minnesota hotel reviews by fellow wanderers

Kahler Grand Hotel
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Staff was very helpful; handicapped bathroom was perfect for Mom's wheelchair. Being able to walk across the street to Mayo was a godsend. Will stay there again when she has her 6 month checkup!"
A verified traveler stayed at Kahler Grand Hotel
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