Book Hotels in Southeast Minnesota, MN
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Top Southeast Minnesota hotels
EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
$114 nightly
The price is $131 total per night from Aug 7 to Aug 8
$131 total
Aug 7 - Aug 8
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Love the rooms. They are very clean. Bed is comfortable."
Reviewed on Jul 6, 2026
Treasure Island Resort & Casino
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $112 total per night from Jul 13 to Jul 14
$112 total
Jul 13 - Jul 14
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
"Great time"
Reviewed on Jul 6, 2026
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Jul 19 to Jul 20
$131 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"The hotel is incredibly clean but badly in need of updating, especially for the price. My bed was not at all comfortable, which is very confounding and disappointing as they have to know most guests are Mayo patients and need good rest more than most. Will not be returning; the Hyatt is only slightly ..."
Reviewed on Jul 7, 2026
Express Suites Riverport Inn & Suites
900 Bruski Dr Winona MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $134 total per night from Jul 8 to Jul 9
$134 total
Jul 8 - Jul 9
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The room had not been cleaned and it was 8:00 pm"
Reviewed on Jun 30, 2026
Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $148 total per night from Jul 31 to Aug 1
$148 total
Jul 31 - Aug 1
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Room needs dome drawer storage. No way to unpack for multi day stay. Hanging is okay//folded and underwater have to be out on window sill."
Reviewed on Jul 5, 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw Rochester MN
$79 nightly
The price is $91 total per night from Jul 12 to Jul 13
$91 total
Jul 12 - Jul 13
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
"The rooms were clean and the staff was very friendly. It was a great breakfast also"
Reviewed on Jul 6, 2026
Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Jul 8 to Jul 9
$160 total
Jul 8 - Jul 9
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Room was clean. Staff was hopeful. Complementary breakfast was good. Parking space appreciated and rate was not terrible. However, it is a very tight lot."
Reviewed on Jul 3, 2026
Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Jul 8 to Jul 9
$97 total
Jul 8 - Jul 9
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"I should have looked at the reviews a bit better before I booked. This is a solid 2-star hotel, but I prefer better. The carpet was a bit sticky (or something) so I bought some slides to wear the next morning. It’s cheap enough, and I guess I got what I paid for. The TV didn’t work right all the ..."
Reviewed on Jul 6, 2026
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jul 19 to Jul 20
$87 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel's 3 indoor pools and gym are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Everything was good. Just wish the breakfast was available a little later. By time I got back from my 6 am PET scan at Mayo clinic I had 10 minutes to have breakfast."
Reviewed on Jul 6, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Minnesota hotels
Red Carpet Inn Rochester
2214 South Broadway Rochester MN
$60 nightly
The price is $69 total per night from Jul 8 to Jul 9
$69 total
Jul 8 - Jul 9
Total with taxes and fees
7.6/10 Good! (545 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southeast Minnesota with star-rating
Check Southeast Minnesota Hotels by Star Rating
4 Star Hotels
8 properties
Recent Southeast Minnesota hotel reviews by fellow wanderers
Hampton Inn Rochester-South
5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"I stayed here two nights while preparing for surgery on the third day. Our room was clean and quiet at night. Air conditioning worked well. Staff was very pleasant. Breakfast was typical, offering basic protein and carbohydrate choices. I met several other individuals connected with Mayo’s exemplary health care delivery system. It was conveniently located for the multiple LYFT rides upon which I depended. Very positive experience. Thank you"
A verified traveler stayed at Hampton Inn Rochester-South
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