Book Hotels in Southeast Minnesota, MN

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Top Southeast Minnesota hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Fully refundable
$111 nightly
The price is $128 total per night from Jan 11 to Jan 12
$128 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great clean and friendly hotel. Rooms were spacious and had a notably nice smell when you first walk in.

Reviewed on Jan 1, 2026

Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $161 total per night from Feb 1 to Feb 2
$161 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Breakfast to go was offered for the volleyball players.

Reviewed on Jan 4, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$80 nightly
The price is $92 total per night from Jan 24 to Jan 25
$92 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The hotel was clean and a friendly staff at check in. We love that the hotel skyway is connected to Mayo, so could walk to appts. inside on a cold day. We also appreciated a noon check out.

Reviewed on Jan 1, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $175 total per night from Jan 11 to Jan 12
$175 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Yes, everything was wonderful. Appreciate that it is right across the street from St. Mary’s.

Reviewed on Jan 9, 2026

Opens in a new windowAspen Suites
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Jan 11 to Jan 12
$146 total
Jan 11 - Jan 12
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
No free breakfast

Reviewed on Jan 8, 2026

Opens in a new windowKahler Grand Hotel
Treasure Island Resort and Casino

Treasure Island Resort and Casino

3 out of 5
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $103 total per night from Jan 14 to Jan 15
$103 total
Jan 14 - Jan 15
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
The room was nice. It was close to the lagoon and restaurants. It was a first floor room which was convenient. The king bed was spacious. We didn’t have a luggage space or suitcase stand for unpacking. We enjoyed the lagoon area, especially the hot tubs and adult only areas. Check in was easy.

Reviewed on Jan 6, 2026

Opens in a new windowTreasure Island Resort and Casino
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $89 total per night from Jan 18 to Jan 19
$89 total
Jan 18 - Jan 19
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Good value for what you get. Clean room, comfortable bed, nice location, and good breakfast. Pool / hot tub area could use better ventilation and updating.

Reviewed on Jan 4, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Jan 11 to Jan 12
$152 total
Jan 11 - Jan 12
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
We enjoy staying at Kahler Inn & Suites. So nice to be so close to Mayo Clinic. You don't have to go outside. You can walk from the hotel tp Mayo. Everyone is so friendly and the breakfast is great!

Reviewed on Jan 9, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jan 18 to Jan 19
$87 total
Jan 18 - Jan 19
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the ...
Friendly staff and very clean

Reviewed on Jan 1, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Minnesota hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeast Minnesota hotel reviews by fellow wanderers

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