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Top Southeast Minnesota hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Fully refundable
$122 nightly
The price is $140 total per night from May 22 to May 23
$140 total
May 22 - May 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
One of the best hotels I've ever stayed at. The staff were very friendly and helpful. The only downside would be the parking situation, which the staff was very helpful in explaining it. I also love how i cant hear people out in the hallway or next door. Lots of privacy and rest.
Reviewed on Apr 25, 2026

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from May 3 to May 4
$160 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
room and staff '
Reviewed on Apr 27, 2026

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from May 3 to May 4
$131 total
May 3 - May 4
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
My room was clean, with a nicely updated, modern feel. I didn't have an opportunity to use the pool, hot tub or fitness room, but they looked great. I didn't need the shuttle service to Mayo - but that is a great amenity! Staff was very friendly and helpful with questions / area recommendations. ...
Reviewed on Apr 27, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from May 3 to May 4
$146 total
May 3 - May 4
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Was put in a room that is used for Expedia customers. Only 2 smaller windows, one foged up. Not a good mattress. 2 outside doors, on both side of our room. Slammed night and day. Rattled our room. Plan on better room next time.
Reviewed on Apr 27, 2026

Treasure Island Resort & Casino
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $88 total per night from May 5 to May 6
$88 total
May 5 - May 6
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
Our room never got cleaned
Reviewed on Apr 28, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from May 10 to May 11
$84 total
May 10 - May 11
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
This is our 3rd time staying we like the quiet environment and location
Reviewed on Apr 27, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from May 3 to May 4
$108 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
Staff there is amazing and and on top of there game and go above and beyond, I would also like to add that Nyiesha the supervisor at the front desk is an amazing asset to your hotel with all the choas with groups and kids last night and the incident that took place she handled her self very well ...
Reviewed on Apr 26, 2026

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from May 2 to May 3
$152 total
May 2 - May 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
I was nice to have breakfast included. Parking was good and in the hotel.
Reviewed on Apr 28, 2026

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $93 total per night from Apr 29 to Apr 30
$93 total
Apr 29 - Apr 30
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
Pool is wonderful with play stuff for kids and a great hot tub. The breakfast area is the cleanest ever! There is no meat for breakfast but otherwise anything you'd need. Great job there! The property is attached to Famous Dave's BBQ and it is GREAT! The property is old but clean. If you had to, ...
Reviewed on Apr 27, 2026
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Minnesota hotels

Red Carpet Inn Rochester
2214 South Broadway Rochester MN
$60 nightly
The price is $69 total per night from Apr 29 to Apr 30
$69 total
Apr 29 - Apr 30
Total with taxes and fees
7.6/10 Good! (539 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southeast Minnesota with star-rating
Check Southeast Minnesota Hotels by Star Rating

4 Star Hotels
7 properties
Recent Southeast Minnesota hotel reviews by fellow wanderers

Kahler Inn and Suites - Mayo Clinic Area
4 out of 5
Posted 4 hours ago
Travelocity Verified Review
"I was nice to have breakfast included. Parking was good and in the hotel. "
A verified traveler stayed at Kahler Inn and Suites - Mayo Clinic Area
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