Book Hotels in Southeast Minnesota, MN

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Jun 26 - Jun 28
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Top Southeast Minnesota hotels

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $195 total per night from Jun 27 to Jun 28
$195 total
Jun 27 - Jun 28
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Staff were uniformly friendly and helpful. That made all the difference for us since we were commuting to/from Mayo Clinic. The free breakfast was decent, but lacked variety, wearing thin during our 1 week stay. Trash was not emptied nearly often enough from the small bins near the elevators. Also ..."

Reviewed on Jun 19, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Treasure Island Resort & Casino

Treasure Island Resort & Casino

3 out of 5
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Jun 23 to Jun 24
$105 total
Jun 23 - Jun 24
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
"Awesome hotel Awesome staff Awesome buffet"

Reviewed on Jun 21, 2026

Opens in a new windowTreasure Island Resort & Casino
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3 out of 5
401 6th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $131 total per night from Jun 28 to Jun 29
$131 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. There's fun for all ages with a children's pool and an arcade/game room, and families will ...
"Twigs is great to have on the property. Great staff, awesome patio and delicious food."

Reviewed on Jun 21, 2026

Opens in a new windowCenterstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

3 out of 5
900 Bruski Dr Winona MN
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $134 total per night from Jun 23 to Jun 24
$134 total
Jun 23 - Jun 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Love the restaurant attached and the rooms are always clean"

Reviewed on Jun 22, 2026

Opens in a new windowExpress Suites Riverport Inn & Suites
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $166 total per night from Jun 23 to Jun 24
$166 total
Jun 23 - Jun 24
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Was not told of two functions that happened when we stayed there. Live bands playing music all night on Thursday and an outside wedding with live music on Friday playing until 10:30pm. We were right above the wedding and had a view from our 3rd floor window. It was extremely loud and very uncomfortable ..."

Reviewed on Jun 21, 2026

Opens in a new windowKahler Grand Hotel
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 out of 5
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $91 total per night from Jun 28 to Jun 29
$91 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
"Clean room and facilities. Although we didn't have kids, the pool area looked fun for the family. Great location to Mayo Clinic. We will be staying there again on our next trip."

Reviewed on Jun 21, 2026

Opens in a new windowBest Western Rochester Hotel Mayo Clinic Area/St. Mary's
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $183 total per night from Jun 23 to Jun 24
$183 total
Jun 23 - Jun 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Air conditioner was so loud I could not sleep and shutting it off was too warm so I basically did not get any sleep."

Reviewed on Jun 21, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Jun 28 to Jun 29
$97 total
Jun 28 - Jun 29
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"Clean room and the staff is nice"

Reviewed on Jun 21, 2026

Opens in a new windowMed City Inn & Suites - Mayo Clinic Area
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $87 total per night from Jul 5 to Jul 6
$87 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel's 3 indoor pools and gym are among the featured amenities. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The mattress on the bed was well used. A dip in the middle. 😏 The shower/tub in the bathroom was slippery when using the shower. My husband almost fell. There was no closet. However, it was quiet and the staff was very gracious. We will stay there again."

Reviewed on Jun 21, 2026

Opens in a new windowLa Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Minnesota hotels

Red Carpet Inn Rochester

Red Carpet Inn Rochester

2214 South Broadway Rochester MN
$60 nightly
The price is $69 total per night from Jun 23 to Jun 24
$69 total
Jun 23 - Jun 24
Total with taxes and fees
7.6/10 Good! (544 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeast Minnesota hotel reviews by fellow wanderers

Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Love the restaurant attached and the rooms are always clean"
A verified traveler stayed at Express Suites Riverport Inn & Suites
Express Suites Riverport Inn & Suites

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