Book Hotels in Southeast Minnesota, MN

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Top Southeast Minnesota hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Fully refundable
$107 nightly
The price is $123 total per night from Jan 30 to Jan 31
$123 total
Jan 30 - Jan 31
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great hotel!

Reviewed on Jan 21, 2026

Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Feb 1 to Feb 2
$149 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Did not have breakfast… but had awesome evening meal…quiet…clean very informed front desk…helpful

Reviewed on Jan 24, 2026

Opens in a new windowAspen Suites
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Jan 31 to Feb 1
$152 total
Jan 31 - Feb 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Front desk was a huge help and extremely kind to us during our visit to Mayo Clinic

Reviewed on Jan 24, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$99 nightly
The price is $114 total per night from Feb 21 to Feb 22
$114 total
Feb 21 - Feb 22
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great room. Nice that checkout is noon. Having Crave Restaurant downstairs is great too.

Reviewed on Jan 20, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 out of 5
123 Fourth Ave. NW Rochester MN
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $122 total per night from Jan 29 to Jan 30
$122 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast and free WiFi. Business travelers can take advantage of the 24-hour business ...
Clean

Reviewed on Jan 27, 2026

Opens in a new windowBrentwood Inn & Suites
Treasure Island Resort and Casino

Treasure Island Resort and Casino

3 out of 5
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $107 total per night from Feb 4 to Feb 5
$107 total
Feb 4 - Feb 5
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
Check in process was a breeze. The lady that checked us in was amazing. Rooms were top notch, newly renovated rooms are a must if you haven’t stayed before.

Reviewed on Jan 26, 2026

Opens in a new windowTreasure Island Resort and Casino
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Jan 29 to Jan 30
$146 total
Jan 29 - Jan 30
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Check in went smooth, the rooms were clean, and we enjoyed the hot tub and sauna

Reviewed on Jan 26, 2026

Opens in a new windowKahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $85 total per night from Jan 31 to Feb 1
$85 total
Jan 31 - Feb 1
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Staff was accommodating, room was good, had some issues. They fixed those promptly. Nice spacious room.

Reviewed on Jan 25, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Jan 29 to Jan 30
$152 total
Jan 29 - Jan 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Clean rooms, breakfast included, great location to Mayo Clinic

Reviewed on Jan 27, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Minnesota hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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