Book Hotels in Southeast Minnesota, MN
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Top Southeast Minnesota hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW, Suite A, Rochester, MN
Fully refundable
$121 nightly
The price is $139 total per night from Oct 11 to Oct 12
$139 total
Oct 11 - Oct 12
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Fine for the basics.
"All the basics are there. Nothing special, certainly not luxurious, but comfortable enough. About a 15-minute walk to Mayo. Few stores or restaurants close by."
Reviewed on Sep 25, 2025

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $82 total per night from Oct 26 to Oct 27
$82 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
"Yes"
Reviewed on Sep 28, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Oct 4 to Oct 5
$160 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"The hotel was clean and the room was clean. However, the couch had a definite smell of urine. It was very strong. It is a pet friendly hotel so I was assuming it was animal urine? It was bothersome, but I did not mention it to the hotel staff."
Reviewed on Sep 12, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
Fully refundable
$80 nightly
The price is $92 total per night from Nov 1 to Nov 2
$92 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Great room."
Reviewed on Sep 26, 2025

Express Suites Riverport Inn & Suites
900 Bruski Dr, Winona, MN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Oct 5 to Oct 6
$123 total
Oct 5 - Oct 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"The staff was awesome. The pool area was great, the room was comfortable, very nice."
Reviewed on Oct 1, 2025

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Oct 23 to Oct 24
$136 total
Oct 23 - Oct 24
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Very nice hotel in downtown Rochester with easy access to Methodist Hospital. We did not use room service or go to the restaurant but it is easily accessible on the main floor lobby level. The hotel staff were uniformly courteous and helpful, even when we called late in the evening. The only disappointment ..."
Reviewed on Sep 27, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
$73 nightly
The price is $84 total per night from Oct 12 to Oct 13
$84 total
Oct 12 - Oct 13
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"Everything was clean , overall a decent facility."
Reviewed on Sep 27, 2025

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Nov 3 to Nov 4
$136 total
Nov 3 - Nov 4
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"Great hotel for our trip to mayo clinic. Very clean and comfortable. If the weather is bad you can get to the clinic without stepping foot outside. Staff is very friendly and helpful"
Reviewed on Sep 27, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $83 total per night from Oct 12 to Oct 13
$83 total
Oct 12 - Oct 13
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the ...
"Gym was good and clean"
Reviewed on Sep 26, 2025
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See all available properties in Southeast Minnesota
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Minnesota hotels

Red Carpet Inn Rochester
2214 South Broadway, Rochester, MN
$60 nightly
The price is $69 total per night from Oct 4 to Oct 5
$69 total
Oct 4 - Oct 5
Total with taxes and fees
7.6/10 Good! (527 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Southeast Minnesota hotel reviews by fellow wanderers

Express Suites Riverport Inn & Suites
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The staff was awesome. The pool area was great, the room was comfortable, very nice."
A verified traveler stayed at Express Suites Riverport Inn & Suites
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