Book Hotels in Southeast Minnesota, MN
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Top Southeast Minnesota hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Fully refundable
$118 nightly
The price is $136 total per night from May 23 to May 24
$136 total
May 23 - May 24
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
One of the best hotels I've ever stayed at. The staff were very friendly and helpful. The only downside would be the parking situation, which the staff was very helpful in explaining it. I also love how i cant hear people out in the hallway or next door. Lots of privacy and rest.
Reviewed on Apr 25, 2026

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$139 nightly
The price is $160 total per night from Apr 26 to Apr 27
$160 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
The rooms were spacious and clean. The front desk and all staff were very helpful and kind to us. The breakfast had alot of good options and good healthy choices! The kids had a wonderful time in the pool. I didnt get to use the gym but it was also very nice and clean. Overall our stay was wonderful ...
Reviewed on Apr 25, 2026

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
1125 2nd St Sw Rochester MN
$94 nightly
The price is $108 total per night from May 8 to May 9
$108 total
May 8 - May 9
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Cookies in the afternoon are great. So is the fruited water.
Reviewed on Apr 24, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Apr 26 to Apr 27
$146 total
Apr 26 - Apr 27
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Room was clean , staff very helpful best part was dinners Ruth Chris steak house located inside hotel ! And location from mayo clinic right across street !
Reviewed on Apr 24, 2026

Treasure Island Resort & Casino
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $88 total per night from May 4 to May 5
$88 total
May 4 - May 5
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
The swim up bar is fun and the outdoor hot tub
Reviewed on Apr 24, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $87 total per night from May 3 to May 4
$87 total
May 3 - May 4
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Very run down. Breakfast was dismal. Got what we paid for, but don't expect typical AmericInn quality.
Reviewed on Apr 25, 2026

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
1517 16th St Sw Rochester MN
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from May 3 to May 4
$108 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Bring the family and enjoy the children's pool, waterslide, and arcade/game room. Enjoy the ...
Good breakfast
Reviewed on Apr 23, 2026

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Apr 26 to Apr 27
$152 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Clean rooms, free breakfast, nice pool, paid parking
Reviewed on Apr 24, 2026

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $89 total per night from May 3 to May 4
$89 total
May 3 - May 4
Total with taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
This has truly become my home away from home while navigating surgeries and appointments at the Mayo Clinic. The staff is incredibly friendly, helpful, and genuinely caring. A special thank you to Kesley, Dequan, and Angel—they each went above and beyond to make sure I felt comfortable and supported. ...
Reviewed on Apr 23, 2026
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See all available properties in Southeast Minnesota
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Minnesota hotels

Red Carpet Inn Rochester
2214 South Broadway Rochester MN
$60 nightly
The price is $69 total per night from Apr 26 to Apr 27
$69 total
Apr 26 - Apr 27
Total with taxes and fees
7.6/10 Good! (539 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southeast Minnesota with star-rating
Check Southeast Minnesota Hotels by Star Rating

4 Star Hotels
7 properties
Recent Southeast Minnesota hotel reviews by fellow wanderers

EVEN Hotel Rochester - Mayo Clinic Area by IHG
5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"One of the best hotels I've ever stayed at. The staff were very friendly and helpful. The only downside would be the parking situation, which the staff was very helpful in explaining it. I also love how i cant hear people out in the hallway or next door. Lots of privacy and rest."
A verified traveler stayed at EVEN Hotel Rochester - Mayo Clinic Area by IHG
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