Book Hotels in Southeast Minnesota, MN
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Top Southeast Minnesota hotels

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $80 total per night from Jul 20 to Jul 21
$80 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
"Very nice hotel for a great price"
Reviewed on Jul 8, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $144 total per night from Jul 13 to Jul 14
$144 total
Jul 13 - Jul 14
Total includes taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"We were not told that the room would not be cleaned for our 3 day visit. Also, the parking ramp filled each night and my husband is handicapped so it was a big issue. But the room itself is awesome and perfect for our needs! Also the staff was nice and the breakfast was nice as well."
Reviewed on Jul 7, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
Fully refundable
$102 nightly
The price is $117 total per night from Aug 3 to Aug 4
$117 total
Aug 3 - Aug 4
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Very nice rooms and staff."
Reviewed on Jul 11, 2025

Aspen Select
1215 2nd St SW, Rochester, MN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Jul 13 to Jul 14
$136 total
Jul 13 - Jul 14
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
"Highly recommended"
Reviewed on Jul 8, 2025

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $135 total per night from Jul 17 to Jul 18
$135 total
Jul 17 - Jul 18
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"wonderful check in. very personal and friendly"
Reviewed on Jul 8, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $90 total per night from Jul 13 to Jul 14
$90 total
Jul 13 - Jul 14
Total includes taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
"Staff was very nice. Comfortable bed. Nice shower. Fairly quiet for being on a busy street. Adequate bkft. No laundry or computer room."
Reviewed on Jul 11, 2025

Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $92 total per night from Jul 13 to Jul 14
$92 total
Jul 13 - Jul 14
Total includes taxes and fees
2 indoor pools, a 24-hour gym, and a hot tub are all featured at this traditional motel. Bring the family and enjoy the children's pool, waterslide, and kid-friendly ...
"Older property but clean and close to Mayo Clinic with a free shuttle which was very appreciated."
Reviewed on Jul 8, 2025

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from Aug 12 to Aug 13
$128 total
Aug 12 - Aug 13
Total includes taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
"If you are going to Mayo it is right across the street."
Reviewed on Jul 10, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$72 nightly
The price is $83 total per night from Jul 20 to Jul 21
$83 total
Jul 20 - Jul 21
Total includes taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the ...
"Friendly staff , clean inside and outside property"
Reviewed on Jul 11, 2025
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See all available properties in Southeast Minnesota
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Minnesota hotels

Red Carpet Inn Rochester
2214 South Broadway, Rochester, MN
$60 nightly
The price is $69 total per night from Jul 13 to Jul 14
$69 total
Jul 13 - Jul 14
Total includes taxes and fees
7.6/10 Good! (516 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Southeast Minnesota with star-rating
Check Southeast Minnesota Hotels by Star Rating

4 Star Hotels
4 properties
Recent Southeast Minnesota hotel reviews by fellow wanderers

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"Friendly staff , clean inside and outside property "
A verified traveler from Sioux Falls stayed at La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
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An Attraction
- Hotels near Mayo Clinic
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