Santee Vacation Packages 2026 from $431

Santee flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Sleep Inn Columbia

Seven Oaks

$431

per person

Aug 20 - Aug 24

found 19 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the business center, express check-in, and conference space. There's a gym on site, and a 24-hour front desk and a snack bar/deli are also provided.

Tru By Hilton Columbia Greystone

$479

per person

Aug 20 - Aug 24

found 19 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. There's a 24-hour gym on site, and a 24-hour front desk and a snack bar/deli are also provided.

Sleep Inn Columbia Airport

$473

per person

Aug 20 - Aug 24

found 19 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Hilton Columbia Center

Downtown Columbia

$600

per person

Aug 20 - Aug 24

found 19 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a 24-hour gym on site, and laundry facilities and concierge services are also offered.

Hyatt Place Columbia/Downtown/The Vista

Downtown Columbia

$573

per person

Aug 20 - Aug 24

found 19 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.

Top Santee hotels deals

Baymont by Wyndham Santee

249 Britain Street Santee SC

Free Cancellation

Reserve now, pay when you stay

$75 nightly

$83 total

Jun 14 - Jun 15

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express check-in and free internet in public areas. There's express check-out and multilingual staff can provide around-the-clock assistance.

Breakfast included

Pet friendly

Fairfield Inn & Suites by Marriott Santee

9074 Old Number Six Hwy Santee SC

Free Cancellation

Reserve now, pay when you stay

$134 nightly

$149 total

Jun 21 - Jun 22

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a snack bar/deli, and a picnic area are also on offer.

Pool

Breakfast included

Tru By Hilton Santee

263 Britain St. and 273 Britain St. Santee SC

Free Cancellation

Reserve now, pay when you stay

$106 nightly

$118 total

Jun 21 - Jun 22

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.

Pool

Breakfast included

Best Western Plus Santee Inn

I 95 Exit 98 Santee SC

Free Cancellation

Reserve now, pay when you stay

$108 nightly

$120 total

Jun 14 - Jun 15

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Pool

Breakfast included

Comfort Inn & Suites Santee

221 Britain St Santee SC

Free Cancellation

$103 nightly

$114 total

Jun 21 - Jun 22

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a lobby fireplace, and laundry facilities are also on offer.

Pool

Breakfast included

Hampton Inn Santee-I-95

9060 Old Number Six Hwy Santee SC

Free Cancellation

Reserve now, pay when you stay

$121 nightly

$134 total

Jun 21 - Jun 22

Total with taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, a terrace, and laundry facilities are also on offer.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Santee State Park

4/5(43 reviews)

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.

Santee Cooper Country Club

4/5(12 reviews)

Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.

Santee National Golf Club

3.5/5(19 reviews)

Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.

Frequently asked questions

How much are vacation packages to Santee?

With vacation packages available from as little as $431, it's not necessary to drain your bank balance for your getaway to Santee. Travelocity can help. Bundle your hotels, flights and tours into a package and walk away with fantastic discounts. The more you book, the more you save.

How long should my Santee vacation be?

Most visitors stay in Santee for approximately 2 nights. That said, travel is all about trying out new things and making memories — why not stay a couple of extra nights so you can do just that?

Where can I get the best vacation package deals for Santee?

One word — Travelocity. With as many as 400 air carriers and 1,000,000 properties worldwide, it's easy to find a Santee package deal that suits your needs.

Why should I book my Santee vacation bundle via Travelocity?

Whether you're planning a month-long vacation or a last-minute trip, we have many alluring destinations to choose from at an affordable price. And on top of that, we offer support 24/7, superb service and a Price Match Guarantee. Save yourself the effort and time and book your dream vacation today.

Can I save on my Santee car rental if I combine it with my hotel or flight?

You sure can with our Santee vacation packages. With one of these, there are lots of ways to make your travel budget go further. Combine any two or more car, hotel, flight and tour bookings and watch your savings grow. With a rental car, all the popular attractions around Santee are an unforgettable road trip away.

What is there to do in Santee?

Santee is full of places to explore, such as Santee State Park and Santee Cooper Country Club. These two popular attractions are on most travelers' itineraries.

Where should I stay when visiting Santee?

The Baymont by Wyndham Santee is the number one choice of many visitors. Book soon before it's too late.