Book Hotels in Vance, SC
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Top Vance hotels

Fairfield Inn & Suites by Marriott Santee
Our room was very clean and the main desk folks were wonderful!
Reviewed on Oct 31, 2025

Hampton Inn Santee-I-95
every thing was great
Reviewed on Oct 26, 2025

Lake Marion Getaway!
Everything was great for the most part, a few dead roaches on the floor, and there was a pair of women’s underwear folded inside one of the dish towels.
Reviewed on Oct 5, 2025

Tru By Hilton Santee
Easy off/on I-95, staff very nicely accommodated my request to refreeze some ice packs I had to keep medicine cold while traveling and quickly retrieved ice packs for me in morning, staff very friendly and efficient. Room was nice and well stocked with towels soaps etc and bed very clean
Reviewed on Oct 29, 2025

Fairfield Inn by Marriott Orangeburg
Hotel is under renovation, but very clean and quiet. The room is large and very clean. Bathrooms with plenty of towels and very clean although a little small. Good variety with the breakfast menu and very clean area. Easy on and off from the interstate price was reasonable for this day.
Reviewed on Oct 28, 2025

Holiday Inn Santee by IHG
Great hotel w
Reviewed on Oct 12, 2025

Baymont by Wyndham Santee
Room very clean, front desk staff with check in very polite and helpful.
Reviewed on Oct 27, 2025

Days Inn by Wyndham St George
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Reviewed on Oct 27, 2025

Cozy 2-bedroom Cottage with Deck and Lake View
Vance Hotel & Travel Guide\n
Visiting Orangeburg? Want a place to lay your head? Travelocity's portal contains plenty of hotels and rooms. You can book around 11 modern accommodations within a short drive of of Vance.
Within an easy drive of Vance, are the Holiday Inn Santee and Hampton Inn Santee I-95.
You should investigate the Hampton Inn Manning along with the Comfort Inn & Suites Santee. The Hampton Inn Manning can be found just 20 miles (34 kilometers) away from the city center of Vance. The Comfort Inn & Suites Santee, is only 5 miles (8 kilometers) away. Another option is to book the Best Western Plus Santee Inn or the Quality Inn And Suites.
Why not see the myriad attractions of South Carolina Midlands during your stay in Vance? Familiarize yourself with South Carolina Midlands's historic mansions and gardens and don't forget to enjoy its rolling hills. Wise visitors in this corner of United States of America adore hiking, zip-lining and horse riding.
The nearest accommodation options in Orangeburg include Santee and Santee. Santee is 4 miles (6 kilometers) to the northwest of Vance, while Santee is 4 miles (6 kilometers) to the northwest. Santee Travelocity-registered lodgings include the Super 8 Santee and Red Roof Inn Santee. The Rodeway Inn and Whitten Inn are a number of the Travelocity-registered hotel options in Santee.
Before your Vance trip comes to an end, why not spend an hour or two enjoying the thrills and spills in the company of local spectators at an exciting game. You'll find Colonial Life Arena 50 miles (84 kilometers) to the northwest of Vance. Travelocity customers who are keen on booking a bed not too far away, make a reservation in the Sheraton Columbia Downtown Hotel or Hilton Columbia Center.
Charleston International Airport is a major entry point for those arriving in Vance. It can be found 45 miles (71 kilometers) from the downtown precinct. For modern travelers who would prefer to find a base nearby, read about Crowne Plaza Charleston Airport - Conv Ctr or Homewood Suites by Hilton Charleston Airport/Conv Center.
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Recent Vance hotel reviews by fellow wanderers

Fairfield Inn & Suites by Marriott Santee
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