Book Hotels in Vance, SC
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Top Vance hotels

Fairfield Inn & Suites by Marriott Santee
Perfect stop!
Reviewed on Feb 23, 2026

Hampton Inn Santee-I-95
Very clean amenities
Reviewed on Feb 18, 2026

Lake Marion Getaway!
Everything was great for the most part, a few dead roaches on the floor, and there was a pair of women’s underwear folded inside one of the dish towels.
Reviewed on Oct 5, 2025

Tru By Hilton Santee
The rooms were meticulous and well adorned. Love the color schemes. The shampoo is amazing. Bathrooms were modern. Really enjoyed the complementary breakfast. A nice variety of breakfast items. Will gladly stay there on my next trip.
Reviewed on Feb 23, 2026

Best Western Plus Santee Inn
Incredibly clean, comfortable and easy access. It’s the perfect half-way stay for us.
Reviewed on Feb 23, 2026

Fairfield Inn by Marriott Orangeburg
General manager, double charged me and won't help now I am looking at filing a complaint with the headquarters office.
Reviewed on Feb 22, 2026

Holiday Inn Santee by IHG
Ashley at the front desk was amazing. Personable and professional…she’s a keeper !!!
Reviewed on Feb 20, 2026

Baymont by Wyndham Santee
Filthy place. Charged me a pet fee even though I didn't stay there.
Reviewed on Feb 24, 2026

Peach Tree Inn
They steal money from people for accidental bookings. Called right away to cancel and they refused and stole my money.
Reviewed on Feb 23, 2026
Vance Hotel & Travel Guide\n
Visiting Orangeburg? Want a place to lay your head? Travelocity's portal contains plenty of hotels and rooms. You can book around 11 modern accommodations within a short drive of of Vance.
Within an easy drive of Vance, are the Holiday Inn Santee and Hampton Inn Santee I-95.
You should investigate the Hampton Inn Manning along with the Comfort Inn & Suites Santee. The Hampton Inn Manning can be found just 20 miles (34 kilometers) away from the city center of Vance. The Comfort Inn & Suites Santee, is only 5 miles (8 kilometers) away. Another option is to book the Best Western Plus Santee Inn or the Quality Inn And Suites.
Why not see the myriad attractions of South Carolina Midlands during your stay in Vance? Familiarize yourself with South Carolina Midlands's historic mansions and gardens and don't forget to enjoy its rolling hills. Wise visitors in this corner of United States of America adore hiking, zip-lining and horse riding.
The nearest accommodation options in Orangeburg include Santee and Santee. Santee is 4 miles (6 kilometers) to the northwest of Vance, while Santee is 4 miles (6 kilometers) to the northwest. Santee Travelocity-registered lodgings include the Super 8 Santee and Red Roof Inn Santee. The Rodeway Inn and Whitten Inn are a number of the Travelocity-registered hotel options in Santee.
Before your Vance trip comes to an end, why not spend an hour or two enjoying the thrills and spills in the company of local spectators at an exciting game. You'll find Colonial Life Arena 50 miles (84 kilometers) to the northwest of Vance. Travelocity customers who are keen on booking a bed not too far away, make a reservation in the Sheraton Columbia Downtown Hotel or Hilton Columbia Center.
Charleston International Airport is a major entry point for those arriving in Vance. It can be found 45 miles (71 kilometers) from the downtown precinct. For modern travelers who would prefer to find a base nearby, read about Crowne Plaza Charleston Airport - Conv Ctr or Homewood Suites by Hilton Charleston Airport/Conv Center.
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Fairfield Inn & Suites by Marriott Santee
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