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Comfort Inn & Suites Santee

2.5 star property
Santee guestrooms with comfy beds

Choose dates to view prices

Photo gallery for Comfort Inn & Suites Santee

Lobby
Free buffet breakfast
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Lobby
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Reviews

8.0 out of 10
Very good

Popular amenities

  • Pool
  • Laundry
  • Gym
  • Housekeeping
  • 24/7 front desk

Explore the area

View in a map
221 Britain St, Santee, SC, 29142
  • Place, Santee Cooper Country Club
    ‪13 min walk‬
  • Place, Santee National Golf Club
    ‪2 min drive‬
  • Place, Santee State Park
    ‪4 min drive‬

Room options

View all photos for Standard Room, 1 King Bed

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Standard Room, 1 King Bed

9.0 out of 10
Wonderful
(18 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 2 Queen Beds

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Standard Room, 2 Queen Beds

7.6 out of 10
Good
(27 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, Non Smoking

8.0 out of 10
Very good
(24 reviews)
  • Sleeps 6
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Room, 1 King Bed, Accessible, Non Smoking

8.4 out of 10
Very good
(5 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Room, 2 Queen Beds, Accessible, Non Smoking

8.8 out of 10
Excellent
(8 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed, Accessible, Non Smoking

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, Multiple Beds, Accessible, Non Smoking

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, Multiple Beds, Accessible, Non Smoking

9.0 out of 10
Wonderful
(4 reviews)
  • Sleeps 6
  • 2 Queen Beds and 1 Double Sofa Bed

Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

  • Sleeps 4
  • 1 Queen Bed and 1 Double Sofa Bed

Suite, 1 King Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

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Total with taxes and fees
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About the neighborhood

Santee

In entertainment district.You'll find Santee Cooper Country Club and Santee National Golf Club within 2 miles (3 km) of this hotel. Santee Town Hall and Santee State Park are also within 2 miles (3 km).

What's nearby

  • Santee Cooper Country Club - 13 min walk - 0.7 miles
  • Santee National Golf Club - 2 min drive - 1.3 miles
  • Santee Town Hall - 3 min drive - 1.3 miles
  • Santee State Park - 4 min drive - 1.5 miles
  • Santee National Wildlife Refuge - 12 min drive - 6.9 miles

Getting around

  • Charleston Intl. Airport (CHS) - 58 min drive

Restaurants

  • ‪McDonald's - ‬4 min walk
  • ‪Bojangles' Famous Chicken 'n Biscuits - ‬11 min walk
  • ‪Starbucks - ‬9 min walk
  • ‪The Lakehouse - ‬7 min drive
  • ‪Cracker Barrel Old Country Store - ‬5 min walk

About this property

Comfort Inn & Suites Santee

Santee guestrooms with comfy beds
Comfort Inn & Suites Santee offers its guests a fitness center and a seasonal outdoor pool. A computer station is on site and WiFi is free in public spaces. There's an onsite business center. Free breakfast is served. A vending machine, multilingual staff, and coffee/tea in a common area are also featured at Comfort Inn & Suites Santee. Limited free parking is available on a first-come, first-served basis. A complete renovation of Comfort Inn & Suites Santee was completed in December 2023.

Smoking is allowed in designated areas at this Santee hotel.

  • 1 building
  • 61 guestrooms or units
  • 3 levels
  • Buffet breakfast (free)
  • Business facilities
  • Coffee in lobby
  • Self-service laundry
  • Front desk (24 hours)
  • Staff is multilingual
  • Front-desk safe
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Television in lobby
  • Elevator
  • Smoking in designated areas
  • Water dispenser
Comfort Inn & Suites Santee offers 61 accommodations with coffee/tea makers and hair dryers. Pillowtop beds feature Frette Italian sheets and premium bedding. Plasma televisions come with satellite channels. Bathrooms include shower/tub combinations.

Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include phones along with free local calls (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Similar properties

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Tru By Hilton Santee
  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
4.6 out of 5, Wonderful, 566 reviews
$98 nightly
The price is $109
Nov 2 - Nov 3
Total with taxes and fees
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Property amenities

Family friendly

  • In-room crib
  • Laundry facilities
  • Seasonal outdoor pool

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Limited onsite parking
  • Wheelchair-accessible parking available

Food and drink

  • Free buffet breakfast
  • Coffee and tea in common areas

Things to do

  • Gym
  • Seasonal outdoor pool
  • TV in common areas

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 4 accessible parking spaces
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom

Room amenities

Entertainment

  • Plasma TV with satellite channels

Bedroom

  • Blackout drapes
  • Free crib
  • Frette Italian sheets
  • Pillowtop mattress

Bathroom

  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Free local calls
  • Heating (climate-controlled)
  • Iron/ironing board
  • Phone

Policies

Check-in

Check-in time starts at 3:00 PM

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children 15 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property reserves the right to pre-authorize the guest's credit card prior to arrival.
Only bookings from non-local guests are accepted; guests whose residence is within 20 mi (32 km) of the property will not be allowed to check in
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, and Discover. Cash is not accepted. This property reserves the right to pre-authorize the guest's credit card prior to arrival. Only bookings from non-local guests are accepted. Guests whose residence is within 20 mi (32 km) of the property will not be allowed to check in.
    This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice).

We should mention

  • The seasonal pool will open in March and close in October.
  • Pool access available from 10 AM to 10 PM.
  • Children 15 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.

Property is also known as

Comfort Inn Hotel Santee
Comfort Inn Santee
Comfort Inn Santee Hotel
Comfort Inn Suites Santee
Comfort & Suites Santee Santee
Comfort Inn & Suites Santee Hotel
Comfort Inn & Suites Santee Santee

Frequently asked questions

How close is Comfort Inn & Suites Santee to the airport?

Comfort Inn & Suites Santee is 60.2 mi (58-min drive) away from the Charleston Intl. Airport (CHS) airport, the closest popular airport to the property.

How much does it cost to stay at Comfort Inn & Suites Santee?

As of Oct 17, 2025, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Santee on Oct 18, 2025 start from $140.67, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Comfort Inn & Suites Santee have an airport shuttle?

Airport shuttle services are not available at Comfort Inn & Suites Santee.

Does Comfort Inn & Suites Santee offer free breakfast?

Yes, Comfort Inn & Suites Santee offers free breakfast.

Is there a casino at Comfort Inn & Suites Santee?

No, there is no casino at this hotel.

What time is check-in at Comfort Inn & Suites Santee?

Check-in begins at 3:00 PM.

Is there free parking at Comfort Inn & Suites Santee?

This hotel offers free self parking.

Does Comfort Inn & Suites Santee have a pool?

Comfort Inn & Suites Santee features a seasonal outdoor pool. Guests can enjoy pool access from 10 AM to 10 PM.

Does Comfort Inn & Suites Santee have a spa?

There are no spa services available at this hotel.

How close is Comfort Inn & Suites Santee to downtown Santee?

Comfort Inn & Suites Santee is 0.2 mi away from Santee.