Cheap Flights to Santee from $124
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How Much Does it Cost To Fly To Santee?
The cheapest prices found with in the last 7 days for return flights were $251 and $124 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply
BOS
Logan Intl.
CAE
Columbia Metropolitan
$251 Roundtrip, found 6 hours ago
$251
Roundtrip
found 6 hours ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| BOS | West Columbia | September 22 to September 29 | $251 |
| DCA | West Columbia | July 17 to July 20 | $255 |
| ORD | West Columbia | August 27 to September 1 | $269 |
| BDL | West Columbia | August 27 to August 30 | $309 |
| EWR | West Columbia | September 12 to September 14 | $329 |
| EWR | West Columbia | September 12 to September 14 | $329 |
| LAX | West Columbia | August 24 to August 30 | $369 |
| TTN | West Columbia | August 18 to August 22 | $388 |
| JFK | West Columbia | July 25 to July 29 | $394 |
| DFW | West Columbia | September 12 to September 17 | $496 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| BDL | West Columbia | June 27 to June 29 | $407 |
| BOS | West Columbia | June 27 to June 29 | $407 |
| TTN | West Columbia | June 27 to June 30 | $443 |
| DCA | West Columbia | June 27 to June 28 | $453 |
| LGA | West Columbia | June 28 to June 30 | $516 |
| EWR | West Columbia | June 28 to June 30 | $612 |
| JFK | West Columbia | June 28 to June 30 | $790 |
| LAX | West Columbia | June 28 to June 30 | $1,009 |
Santee Flight Information
Traveling to | Santee |
|---|---|
Lowest Price | $251 |
Number of Airlines Serving | |
Airlines Serving | American Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Santee Accommodation Deals
Baymont by Wyndham Santee
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from Jun 28 to Jun 29
$83 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,473 reviews)
"Musty, dingy environment."
Reviewed on Jun 24, 2026
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from Jun 28 to Jun 29
$70 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
$63 nightly
The price is $70 total per night from Jul 5 to Jul 6
$70 total
Jul 5 - Jul 6
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (743 reviews)
"Shower did not work toilet did not flush… Breakfast was super limited and there were 15 flies flying around in the breakfast room… The young lady behind the front desk said the door was just hard to push open when it was actually locked! Then tried to accuse me of not pushing hard enough when I clearly ..."
Reviewed on Jun 24, 2026
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Santee/I-95
9125 Old Highway 6 Santee SC
$64 nightly
The price is $71 total per night from Jul 1 to Jul 2
$71 total
Jul 1 - Jul 2
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.8/10 (468 reviews)
"Breakfast was terrible. Toilet ran all night."
Reviewed on Jun 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Santee
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from Jun 28 to Jun 29
$70 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Comfort Inn & Suites Santee
221 Britain St Santee SC
$105 nightly
The price is $117 total per night from Jul 19 to Jul 20
$117 total
Jul 19 - Jul 20
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,005 reviews)
"We stopped here on our way from Florida to New Jersey. We were there for about 7 hours total. The person at the front desk was very nice, bed was comfy, area was safe. Glad we stayed here for less money than other places nearby."
Reviewed on Jun 24, 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from Jun 28 to Jun 29
$83 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,473 reviews)
"Musty, dingy environment."
Reviewed on Jun 24, 2026
Save an average of 15% on thousands of hotels when you're signed in
Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
$72 nightly
The price is $80 total per night from Jul 20 to Jul 21
$80 total
Jul 20 - Jul 21
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a nightclub. Popular attractions Santee Cooper Country Club and Santee National ...
6.4/10 (566 reviews)
"John, the General Manager, was very welcoming and ensured that we had a wonderful stay."
Reviewed on Jun 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Santee
Comfort Inn & Suites Santee
221 Britain St Santee SC
$105 nightly
The price is $117 total per night from Jul 19 to Jul 20
$117 total
Jul 19 - Jul 20
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,005 reviews)
"We stopped here on our way from Florida to New Jersey. We were there for about 7 hours total. The person at the front desk was very nice, bed was comfy, area was safe. Glad we stayed here for less money than other places nearby."
Reviewed on Jun 24, 2026
Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
$125 nightly
The price is $138 total per night from Jul 6 to Jul 7
$138 total
Jul 6 - Jul 7
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,001 reviews)
"Friendly stall, plenty of parking, nice room and super convenient for highway travel. I would stay again."
Reviewed on Jun 24, 2026
Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
$112 nightly
The price is $124 total per night from Jun 28 to Jun 29
$124 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,001 reviews)
"Staff was so friendly and helpful. Room was very clean as well as the grounds. Pool was so relaxing and there was even I float the I could use. Air conditioning was a little loud and the refrigerator was in the TV stand which I didn't see. Typical breakfast-- bunch of high processed high sugar food. ..."
Reviewed on Jun 24, 2026
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
$104 nightly
The price is $115 total per night from Jun 28 to Jun 29
$115 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,000 reviews)
"Beds & pillows are very comfortable. Amenities needs some upgrading....I brewed a keurig cup coffee & grinds were in the cup. Toilet to upgrade & shower curtain too small. But very clean!"
Reviewed on May 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Santee Flight and Hotel Packages
Santee flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Need a Car For After Your Flight?
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Plane Tickets To Santee
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