Cheap Flights to Santee from $160
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How Much Does it Cost To Fly To Santee?
The cheapest prices found with in the last 7 days for return flights were $249 and $160 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply
IAD
Washington Dulles Intl.
CAE
Columbia Metropolitan
$249 Roundtrip, found 15 hours ago
$249
Roundtrip
found 15 hours ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| LGA | West Columbia | May 8 to May 11 | $259 |
| DCA | West Columbia | April 16 to April 19 | $260 |
| ORD | West Columbia | June 5 to June 7 | $274 |
| BOS | West Columbia | May 28 to June 2 | $275 |
| EWR | West Columbia | April 25 to April 27 | $280 |
| JFK | West Columbia | May 29 to June 1 | $283 |
| BDL | West Columbia | June 5 to June 13 | $313 |
| LAX | West Columbia | May 29 to June 1 | $389 |
| PHL | West Columbia | May 1 to May 2 | $417 |
| DFW | West Columbia | April 27 to April 29 | $608 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DFW | West Columbia | March 29 to March 31 | $607 |
Santee Flight Information
Traveling to | Santee |
|---|---|
Lowest Price | $249 |
Number of Airlines Serving | |
Airlines Serving | Delta, United |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Santee Accommodation Deals
Baymont by Wyndham Santee
249 Britain Street Santee SC
$80 nightly
The price is $89 total per night from Mar 29 to Mar 30
$89 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
$63 nightly
The price is $70 total per night from Mar 29 to Mar 30
$70 total
Mar 29 - Mar 30
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (710 reviews)
Second time staying here. Adequate for the cost and our needs. Great location; close proximity to amenities. Easy check-in; friendly, courteous employees. Clean, large ground floor room with comfortable bed, small fridge and microwave. Convenient parking right in front of room.
Reviewed on Mar 24, 2026
Super 8 by Wyndham Santee
9125 Old Highway 6 Santee SC
$75 nightly
The price is $83 total per night from Mar 29 to Mar 30
$83 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.8/10 (446 reviews)
I originally booked one night, but because the entire staff made me feel relaxed, I decided to stay an additional night. The lady at the check-in desk said they try to get good reviews from guests. I needed to do a Microsoft Teams interview, so I needed a really good internet connection. The pool ...
Reviewed on Mar 11, 2026
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Econo Lodge Santee
9112 Old 6 Highway Santee SC
$59 nightly
The price is $66 total per night from Apr 8 to Apr 9
$66 total
Apr 8 - Apr 9
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Santee Cooper Country Club and Santee National Golf ...
6.4/10 (312 reviews)
Very clean room, fast staff, a lot of food spots nearby!
Reviewed on Mar 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Santee
Comfort Inn & Suites Santee
221 Britain St Santee SC
$121 nightly
The price is $134 total per night from Apr 13 to Apr 14
$134 total
Apr 13 - Apr 14
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,000 reviews)
We call it the discomfort inn. Never again. I couldn’t book the two places we frequent so we chose here and it’s a no in so many ways. I am now in Savannah for the same price with hotel.com in a beautiful hotel.. Clean your windows, put in room thermostats, add a ceiling fan for air circulation and ...
Reviewed on Mar 23, 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
$80 nightly
The price is $89 total per night from Mar 29 to Mar 30
$89 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a nightclub. Popular attractions Santee Cooper Country Club and Santee National ...
6.4/10 (553 reviews)
After booking the room and later reading reviews, I was concerned. I met with the desk clerk prior to checking in and asked to see the room first due to the reviews. He was more than happy to allow it, although he stated this is NOT the room i would be staying in, but could expect the same level ...
Reviewed on Mar 13, 2026
Save an average of 15% on thousands of hotels when you're signed in
Econo Lodge Santee
9112 Old 6 Highway Santee SC
$59 nightly
The price is $66 total per night from Apr 8 to Apr 9
$66 total
Apr 8 - Apr 9
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Santee Cooper Country Club and Santee National Golf ...
6.4/10 (312 reviews)
Very clean room, fast staff, a lot of food spots nearby!
Reviewed on Mar 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Santee
Comfort Inn & Suites Santee
221 Britain St Santee SC
$121 nightly
The price is $134 total per night from Apr 13 to Apr 14
$134 total
Apr 13 - Apr 14
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,000 reviews)
We call it the discomfort inn. Never again. I couldn’t book the two places we frequent so we chose here and it’s a no in so many ways. I am now in Savannah for the same price with hotel.com in a beautiful hotel.. Clean your windows, put in room thermostats, add a ceiling fan for air circulation and ...
Reviewed on Mar 23, 2026
Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
$135 nightly
The price is $150 total per night from Apr 5 to Apr 6
$150 total
Apr 5 - Apr 6
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,000 reviews)
This property is AMAZING!! The rooms are beautiful and well maintained. The breakfast (included) was exceptional as were the ladies preparing it and maintaining the area for cleanliness. The entire staff were helpful, polite and professional. We recommend it highly!!
Reviewed on Mar 22, 2026
Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
$119 nightly
The price is $132 total per night from Apr 12 to Apr 13
$132 total
Apr 12 - Apr 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,000 reviews)
N/a
Reviewed on Mar 22, 2026
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
$139 nightly
The price is $154 total per night from Apr 13 to Apr 14
$154 total
Apr 13 - Apr 14
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,000 reviews)
The property is very nice and convenient for the family to visit with. My only issue was that there wasn’t enough soap in the shower for two people but overall we enjoyed our stay.
Reviewed on Mar 22, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Santee Flight and Hotel Packages
Santee flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Need a Car For After Your Flight?
Economy
Chevrolet Spark or similar
Compact
Ford Focus or similar
Midsize
Toyota Corolla or similar
SUV
Jeep Compass or similar
Plane Tickets To Santee
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santee. Browse through our inventory to explore a wide range of cheap flights to Santee to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santee as you anxiously await to exit the plane and explore what Santee has to offer. Considering all the amazing local food and culture in Santee, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santee to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santee without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santee with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santee today!
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