Cheap Flights to Santee from $122

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How Much Does it Cost To Fly To Santee?

The cheapest prices found with in the last 7 days for return flights were $189 and $122 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
DCAWest ColumbiaJanuary 16 to January 19$189
BDLWest ColumbiaJanuary 13 to January 31$207
LGAWest ColumbiaDecember 3 to December 20$209
ORDWest ColumbiaDecember 16 to December 25$209
EWRWest ColumbiaJanuary 7 to January 10$219
JFKWest ColumbiaDecember 3 to December 8$229
BOSWest ColumbiaNovember 20 to November 27$248
LAXWest ColumbiaDecember 9 to December 15$309
PHLWest ColumbiaNovember 27 to November 27$349
DFWWest ColumbiaJanuary 1 to January 18$351
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
BDLWest ColumbiaNovember 15 to November 18$305
DCAWest ColumbiaNovember 15 to November 17$307
JFKWest ColumbiaNovember 15 to November 24$309
JFKWest ColumbiaNovember 15 to November 24$309
ORDWest ColumbiaNovember 14 to November 17$324
BOSWest ColumbiaNovember 14 to November 17$344
EWRWest ColumbiaNovember 14 to November 16$356
LAXWest ColumbiaNovember 15 to December 5$375
PHLWest ColumbiaNovember 15 to December 6$416
DFWWest ColumbiaNovember 15 to November 24$566
*Prices include taxes and fees

Santee Flight Information

Traveling to
Santee
Lowest Price
$189
Number of Airlines Serving
Airlines Serving
Delta
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Santee Accommodation Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
$75 nightly
The price is $83 total per night from Nov 10 to Nov 11
$83 total
Nov 10 - Nov 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,391 reviews)
Room is very clean. Good for the prize. I recommend this place

Reviewed on Nov 9, 2025

Opens in a new windowBaymont by Wyndham Santee
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6, Santee, SC
$63 nightly
The price is $70 total per night from Nov 10 to Nov 11
$70 total
Nov 10 - Nov 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (632 reviews)
This was a good place to stay for a quick overnight. Beds were comfortable, but towels were small and rough. Front staff were adequate, but they seemed busy. Not many amenities. You get what you pay for!

Reviewed on Oct 31, 2025

Opens in a new windowRed Roof Inn Santee
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy, Santee, SC
$61 nightly
The price is $68 total per night from Dec 9 to Dec 10
$68 total
Dec 9 - Dec 10
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (664 reviews)
First impression wasn’t great having to guess where the office was at this small, single-level motel. It was nice however, not having to climb stairs and having a reserved parking spot right at your front door. Having stayed at several other budget hotels in the general area, entering the room was ...

Reviewed on Oct 30, 2025

Opens in a new windowTravelodge by Wyndham Santee
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Super 8 by Wyndham Santee

Super 8 by Wyndham Santee

2 out of 5
9125 Old Highway 6, Santee, SC
$70 nightly
The price is $78 total per night from Nov 12 to Nov 13
$78 total
Nov 12 - Nov 13
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.6/10 (436 reviews)
Older property but was clean. Bathroom door didn't shut easily (you really had to slam it). Bathroom needs updating. Couch was stained but we didn't need it anyway. Bed was just okay.

Reviewed on Aug 18, 2025

Opens in a new windowSuper 8 by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Santee

Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6, Santee, SC
$63 nightly
The price is $70 total per night from Nov 10 to Nov 11
$70 total
Nov 10 - Nov 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (632 reviews)
This was a good place to stay for a quick overnight. Beds were comfortable, but towels were small and rough. Front staff were adequate, but they seemed busy. Not many amenities. You get what you pay for!

Reviewed on Oct 31, 2025

Opens in a new windowRed Roof Inn Santee
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
$105 nightly
The price is $117 total per night from Nov 17 to Nov 18
$117 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,003 reviews)
The room was clean the bed was comfortable, great pillows. A chocolate chip cookie from the lobby was very nice to have. I got in late and was very tired. Great little refrigerator too. For the price you could not go wrong! Lady at the desk was definitely pleasant. She gave me a first floor room ...

Reviewed on Oct 28, 2025

Opens in a new windowComfort Inn & Suites Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street, Santee, SC
$75 nightly
The price is $83 total per night from Nov 10 to Nov 11
$83 total
Nov 10 - Nov 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,391 reviews)
Room is very clean. Good for the prize. I recommend this place

Reviewed on Nov 9, 2025

Opens in a new windowBaymont by Wyndham Santee
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Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

2 out of 5
123 Mall Street, Santee, SC
$71 nightly
The price is $78 total per night from Nov 16 to Nov 17
$78 total
Nov 16 - Nov 17
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.2/10 (538 reviews)
The grounds and property were clean and you could tell they take pride in what they're offering.

Reviewed on Sep 9, 2025

Opens in a new windowRamada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St, Santee, SC
$105 nightly
The price is $117 total per night from Nov 17 to Nov 18
$117 total
Nov 17 - Nov 18
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,003 reviews)
The room was clean the bed was comfortable, great pillows. A chocolate chip cookie from the lobby was very nice to have. I got in late and was very tired. Great little refrigerator too. For the price you could not go wrong! Lady at the desk was definitely pleasant. She gave me a first floor room ...

Reviewed on Oct 28, 2025

Opens in a new windowComfort Inn & Suites Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy, Santee, SC
$112 nightly
The price is $124 total per night from Dec 9 to Dec 10
$124 total
Dec 9 - Dec 10
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,003 reviews)
Breakfast looked excellent

Reviewed on Nov 2, 2025

Opens in a new windowHampton Inn Santee-I-95
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98, Santee, SC
$118 nightly
The price is $131 total per night from Nov 16 to Nov 17
$131 total
Nov 16 - Nov 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,002 reviews)
Room was nice and friendly staff!

Reviewed on Nov 1, 2025

Opens in a new windowBest Western Plus Santee Inn
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Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd, Santee, SC
$118 nightly
The price is $131 total per night from Dec 8 to Dec 9
$131 total
Dec 8 - Dec 9
Total with taxes and fees
Stay at this 3-star golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (960 reviews)
Great hotel w

Reviewed on Oct 12, 2025

Opens in a new windowHoliday Inn Santee by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Santee Flight and Hotel Packages

Santee flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Orangeburg Inn & Suites
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Plane Tickets To Santee

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.