Cheap Flights to Santee from $116
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How Much Does it Cost To Fly To Santee?
The cheapest prices found with in the last 7 days for return flights were $251 and $116 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply
BOS
Logan Intl.
CAE
Columbia Metropolitan
$251 Roundtrip, found 1 day ago
$251
Roundtrip
found 1 day ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| BOS | West Columbia | August 18 to August 22 | $251 |
| DCA | West Columbia | July 9 to July 13 | $255 |
| ORD | West Columbia | July 7 to July 12 | $275 |
| EWR | West Columbia | September 12 to September 14 | $329 |
| EWR | West Columbia | September 12 to September 14 | $329 |
| BDL | West Columbia | August 8 to August 10 | $342 |
| LAX | West Columbia | August 27 to August 30 | $379 |
| TTN | West Columbia | July 10 to July 15 | $417 |
| JFK | West Columbia | September 12 to September 14 | $422 |
| DFW | West Columbia | August 4 to August 7 | $553 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DCA | West Columbia | June 20 to June 21 | $347 |
| ORD | West Columbia | June 20 to June 24 | $388 |
| LGA | West Columbia | June 19 to June 21 | $533 |
| LAX | West Columbia | June 21 to June 28 | $756 |
Santee Flight Information
Traveling to | Santee |
|---|---|
Lowest Price | $251 |
Number of Airlines Serving | |
Airlines Serving | American Airlines |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Santee Accommodation Deals
Baymont by Wyndham Santee
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from Jun 15 to Jun 16
$83 total
Jun 15 - Jun 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,467 reviews)
"it's old but clean Breakfast was good."
Reviewed on Jun 12, 2026
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from Jun 17 to Jun 18
$70 total
Jun 17 - Jun 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
$60 nightly
The price is $67 total per night from Jul 14 to Jul 15
$67 total
Jul 14 - Jul 15
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (739 reviews)
"Room was very worn. Large deposits in corners of bath, tile broken or missing. Could not shower as handicap wouldn’t allow tub use. Had stayed there years back, quite disappointing"
Reviewed on Jun 1, 2026
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Santee/I-95
9125 Old Highway 6 Santee SC
$64 nightly
The price is $71 total per night from Jun 21 to Jun 22
$71 total
Jun 21 - Jun 22
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.8/10 (467 reviews)
"Mr Barry was so sweet! Make sure to say hi to his bird! We felt safe and enjoyed our stay. Plenty of food options in walking distance. Great breakfast options too."
Reviewed on Jun 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Santee
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from Jun 17 to Jun 18
$70 total
Jun 17 - Jun 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Comfort Inn & Suites Santee
221 Britain St Santee SC
$103 nightly
The price is $114 total per night from Jun 21 to Jun 22
$114 total
Jun 21 - Jun 22
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,010 reviews)
"Clean rooms that were connecting which we requested. Friendly staff. Good breakfast. Met all our needs while traveling with six children."
Reviewed on Jun 11, 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from Jun 15 to Jun 16
$83 total
Jun 15 - Jun 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,467 reviews)
"it's old but clean Breakfast was good."
Reviewed on Jun 12, 2026
Save an average of 15% on thousands of hotels when you're signed in
Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
$72 nightly
The price is $80 total per night from Jul 5 to Jul 6
$80 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a nightclub. Popular attractions Santee Cooper Country Club and Santee National ...
6.4/10 (564 reviews)
"The room was very clean, the staff very friendly, and the restaurant/bar had good food and drinks and the pool tables added a unique touch!"
Reviewed on Jun 1, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Santee
Comfort Inn & Suites Santee
221 Britain St Santee SC
$103 nightly
The price is $114 total per night from Jun 21 to Jun 22
$114 total
Jun 21 - Jun 22
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,010 reviews)
"Clean rooms that were connecting which we requested. Friendly staff. Good breakfast. Met all our needs while traveling with six children."
Reviewed on Jun 11, 2026
Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
$121 nightly
The price is $134 total per night from Jun 21 to Jun 22
$134 total
Jun 21 - Jun 22
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,008 reviews)
"We brought our pup and had a lovely stay."
Reviewed on Jun 11, 2026
Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
$108 nightly
The price is $120 total per night from Jun 18 to Jun 19
$120 total
Jun 18 - Jun 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,009 reviews)
"Great parking and staff, clean room, good breakfast. Stayed there before; will stay there again."
Reviewed on Jun 13, 2026
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
$102 nightly
The price is $113 total per night from Jun 28 to Jun 29
$113 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,002 reviews)
"Beds & pillows are very comfortable. Amenities needs some upgrading....I brewed a keurig cup coffee & grinds were in the cup. Toilet to upgrade & shower curtain too small. But very clean!"
Reviewed on May 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Santee Flight and Hotel Packages
Santee flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Need a Car For After Your Flight?
Special
Columbia, South Carolina, USA
$58
$155 total
found 3 days ago
Mini Van
West Columbia, South Carolina, USA
$60
$199 total
found 3 days ago
Standard Pickup Regular Cab
West Columbia, South Carolina, USA
$61
$201 total
found 3 days ago
Economy
Columbia, South Carolina, USA
$63
$167 total
found 3 days ago
Lowest prices found within the past 3 days. Prices and availability subject to change. Additional terms may apply.
Plane Tickets To Santee
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santee. Browse through our inventory to explore a wide range of cheap flights to Santee to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santee as you anxiously await to exit the plane and explore what Santee has to offer. Considering all the amazing local food and culture in Santee, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santee to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santee without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santee with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santee today!
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