Cheap Flights to Santee from $160

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How Much Does it Cost To Fly To Santee?

The cheapest prices found with in the last 7 days for return flights were $291 and $160 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
BOSWest ColumbiaDecember 12 to December 15$291
DCAWest ColumbiaDecember 9 to December 13$329
LGAWest ColumbiaDecember 4 to December 6$339
ORDWest ColumbiaDecember 24 to December 29$342
BDLWest ColumbiaDecember 3 to December 6$349
EWRWest ColumbiaNovember 23 to December 2$356
JFKWest ColumbiaNovember 23 to December 2$365
LAXWest ColumbiaDecember 5 to December 11$416
DFWWest ColumbiaDecember 14 to December 21$469
PHLWest ColumbiaDecember 18 to December 29$498
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
BDLWest ColumbiaNovember 13 to November 15$449
EWRWest ColumbiaNovember 14 to November 18$484
EWRWest ColumbiaNovember 14 to November 18$484
JFKWest ColumbiaNovember 14 to November 15$489
DCAWest ColumbiaNovember 13 to November 15$494
TTNWest ColumbiaNovember 14 to November 17$650
*Prices include taxes and fees

Santee Flight Information

Traveling to
Santee
Lowest Price
$291
Number of Airlines Serving
Airlines Serving
American Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Santee Accommodation Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
$80 nightly
The price is $89 total per night from Nov 10 to Nov 11
$89 total
Nov 10 - Nov 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,516 reviews)
"Nice clean property. Close to 95 and Cracker Barrel. The property is dated, but a good value. I have stayed here several times, and will stay there again. Breakfast is OK, just enough to get you back on the road again."

Reviewed on Nov 9, 2026

Opens in a new windowBaymont by Wyndham Santee
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from Nov 15 to Nov 16
$70 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Opens in a new windowRed Roof Inn Santee
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy Santee SC
$64 nightly
The price is $71 total per night from Nov 10 to Nov 11
$71 total
Nov 10 - Nov 11
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
Opens in a new windowTravelodge by Wyndham Santee
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95

2 out of 5
9125 Old Highway 6 Santee SC
$64 nightly
The price is $71 total per night from Nov 15 to Nov 16
$71 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
Opens in a new windowSuper 8 by Wyndham Santee/I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Santee

Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from Nov 15 to Nov 16
$70 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Opens in a new windowRed Roof Inn Santee
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
$102 nightly
The price is $113 total per night from Nov 29 to Nov 30
$113 total
Nov 29 - Nov 30
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
Opens in a new windowComfort Inn & Suites Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
$80 nightly
The price is $89 total per night from Nov 10 to Nov 11
$89 total
Nov 10 - Nov 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,516 reviews)
"Nice clean property. Close to 95 and Cracker Barrel. The property is dated, but a good value. I have stayed here several times, and will stay there again. Breakfast is OK, just enough to get you back on the road again."

Reviewed on Nov 9, 2026

Opens in a new windowBaymont by Wyndham Santee
Save an average of 15% on thousands of hotels when you're signed in
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

2 out of 5
123 Mall Street Santee SC
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a nightclub. Popular attractions Santee Cooper Country Club and Santee National ...
6.4/10 (597 reviews)
"The room we stayed in was clean.The only downside was that they were doing some remodeling to the place and a worker knocked on our door for some reason, don't know why he didn't speak English."

Reviewed on Oct 22, 2026

Opens in a new windowRamada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
$102 nightly
The price is $113 total per night from Nov 29 to Nov 30
$113 total
Nov 29 - Nov 30
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
Opens in a new windowComfort Inn & Suites Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
$123 nightly
The price is $137 total per night from Nov 25 to Nov 26
$137 total
Nov 25 - Nov 26
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
Opens in a new windowHampton Inn Santee-I-95
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
$118 nightly
The price is $131 total per night from Nov 15 to Nov 16
$131 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,002 reviews)
"Buffet breakfast. Friendly staff. Easy access off Route 95. Pet friendly."

Reviewed on Nov 9, 2026

Opens in a new windowBest Western Plus Santee Inn
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Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd Santee SC
$120 nightly
The price is $133 total per night from Nov 15 to Nov 16
$133 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Opens in a new windowHoliday Inn Santee by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Santee Flight and Hotel Packages

Santee flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Ashburn Inn Manning I 95
Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG
Hyatt Place Columbia/Downtown/The Vista
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Need a Car For After Your Flight?

Plane Tickets To Santee

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When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santee to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santee without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santee with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santee today!

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.