Cheap Flights to Santee from $99

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How Much Does it Cost To Fly To Santee?

The cheapest prices found with in the last 7 days for return flights were $189 and $99 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
ORDWest ColumbiaMarch 24 to March 25$201
BDLWest ColumbiaMarch 10 to March 17$207
DCAWest ColumbiaMarch 8 to March 19$209
LGAWest ColumbiaMarch 18 to April 2$209
BOSWest ColumbiaMay 2 to May 30$211
EWRWest ColumbiaMarch 12 to March 16$214
JFKWest ColumbiaApril 14 to April 21$229
PHLWest ColumbiaApril 23 to April 29$328
LAXWest ColumbiaApril 6 to April 13$331
DFWWest ColumbiaMarch 11 to March 14$429
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
DCAWest ColumbiaFebruary 14 to February 17$287
BDLWest ColumbiaFebruary 14 to February 15$335
EWRWest ColumbiaFebruary 14 to February 16$389
EWRWest ColumbiaFebruary 14 to February 16$389
JFKWest ColumbiaFebruary 14 to February 15$396
ORDWest ColumbiaFebruary 14 to February 15$405
LAXWest ColumbiaFebruary 14 to February 19$427
PHLWest ColumbiaFebruary 13 to February 15$459
DFWWest ColumbiaFebruary 14 to February 17$524
BOSWest ColumbiaFebruary 14 to February 15$652
*Prices include taxes and fees

Santee Flight Information

Traveling to
Santee
Lowest Price
$189
Number of Airlines Serving
Airlines Serving
Delta, United
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Santee Accommodation Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from Feb 10 to Feb 11
$83 total
Feb 10 - Feb 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,426 reviews)
Room was clean. Staff helpful

Reviewed on Feb 7, 2026

Opens in a new windowBaymont by Wyndham Santee
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
$65 nightly
The price is $72 total per night from Feb 15 to Feb 16
$72 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (642 reviews)
Very clean and well kept up room. It was quiet despite having people in rooms on both sides of us. Highly recommend this place for the value.

Reviewed on Jan 4, 2026

Opens in a new windowRed Roof Inn Santee
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy Santee SC
$62 nightly
The price is $69 total per night from Feb 10 to Feb 11
$69 total
Feb 10 - Feb 11
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (694 reviews)
Clean and friendly

Reviewed on Jan 31, 2026

Opens in a new windowTravelodge by Wyndham Santee
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Santee

Super 8 by Wyndham Santee

2 out of 5
9125 Old Highway 6 Santee SC
$75 nightly
The price is $83 total per night from Feb 10 to Feb 11
$83 total
Feb 10 - Feb 11
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.6/10 (441 reviews)
The staff was very friendly and helpful. Room was clean and beds were so comfortable.

Reviewed on Dec 8, 2025

Opens in a new windowSuper 8 by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Santee

Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
$65 nightly
The price is $72 total per night from Feb 15 to Feb 16
$72 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (642 reviews)
Very clean and well kept up room. It was quiet despite having people in rooms on both sides of us. Highly recommend this place for the value.

Reviewed on Jan 4, 2026

Opens in a new windowRed Roof Inn Santee
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
$100 nightly
The price is $111 total per night from Feb 15 to Feb 16
$111 total
Feb 15 - Feb 16
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,004 reviews)
Place was nice and will stay there again.

Reviewed on Feb 6, 2026

Opens in a new windowComfort Inn & Suites Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from Feb 10 to Feb 11
$83 total
Feb 10 - Feb 11
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,426 reviews)
Room was clean. Staff helpful

Reviewed on Feb 7, 2026

Opens in a new windowBaymont by Wyndham Santee
Save an average of 15% on thousands of hotels when you're signed in
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

2 out of 5
123 Mall Street Santee SC
$79 nightly
The price is $87 total per night from Feb 15 to Feb 16
$87 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Santee Cooper Country Club and Santee ...
6.2/10 (549 reviews)
The room was the cleanest of many hotels on a long road trip; cleaner than fancier hotels. Don't freak out when you drive up....it looks like an abandoned building...but the rooms are nice

Reviewed on Jan 4, 2026

Opens in a new windowRamada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
$100 nightly
The price is $111 total per night from Feb 15 to Feb 16
$111 total
Feb 15 - Feb 16
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,004 reviews)
Place was nice and will stay there again.

Reviewed on Feb 6, 2026

Opens in a new windowComfort Inn & Suites Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
$132 nightly
The price is $146 total per night from Feb 22 to Feb 23
$146 total
Feb 22 - Feb 23
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,000 reviews)
Everything was great

Reviewed on Feb 1, 2026

Opens in a new windowHampton Inn Santee-I-95
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
$119 nightly
The price is $132 total per night from Feb 15 to Feb 16
$132 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,001 reviews)
yes

Reviewed on Jan 21, 2026

Opens in a new windowBest Western Plus Santee Inn
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd Santee SC
$130 nightly
The price is $144 total per night from Feb 16 to Feb 17
$144 total
Feb 16 - Feb 17
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (999 reviews)
Bed was so comfy….clean. Great staff.

Reviewed on Feb 4, 2026

Opens in a new windowHoliday Inn Santee by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Santee Flight and Hotel Packages

Santee flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Sleep Inn Airport
Hyatt Place Columbia/Downtown/The Vista
Hilton Columbia Center
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Need a Car For After Your Flight?

Lowest prices found within the past 4 days. Prices and availability subject to change. Additional terms may apply.

Plane Tickets To Santee

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santee. Browse through our inventory to explore a wide range of cheap flights to Santee to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santee as you anxiously await to exit the plane and explore what Santee has to offer. Considering all the amazing local food and culture in Santee, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santee to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santee without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santee with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santee today!

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.