Cheap Flights to Santee from $125
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How Much Does it Cost To Fly To Santee?
The cheapest prices found with in the last 7 days for return flights were $188 and $125 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply
IND
Indianapolis Intl.
CAE
Columbia Metropolitan
$188 Roundtrip, found 1 day ago
$188
Roundtrip
found 1 day ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DCA | West Columbia | January 8 to January 12 | $192 |
| JFK | West Columbia | January 17 to January 18 | $201 |
| JFK | West Columbia | January 17 to January 18 | $201 |
| BDL | West Columbia | January 17 to January 31 | $207 |
| EWR | West Columbia | January 8 to January 11 | $214 |
| ORD | West Columbia | January 16 to January 18 | $215 |
| BOS | West Columbia | February 26 to March 2 | $251 |
| LAX | West Columbia | February 1 to February 9 | $329 |
| PHL | West Columbia | January 1 to January 1 | $355 |
| DFW | West Columbia | January 17 to January 18 | $377 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| ORD | West Columbia | December 26 to January 10 | $384 |
| DCA | West Columbia | December 26 to December 29 | $393 |
| JFK | West Columbia | December 26 to January 6 | $432 |
| JFK | West Columbia | December 26 to January 6 | $432 |
| BDL | West Columbia | December 26 to January 17 | $499 |
| LAX | West Columbia | December 26 to January 1 | $529 |
| PHL | West Columbia | December 26 to December 31 | $544 |
| EWR | West Columbia | December 28 to December 29 | $693 |
Santee Flight Information
Traveling to | Santee |
|---|---|
Lowest Price | $188 |
Number of Airlines Serving | |
Airlines Serving | Delta |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Santee Accommodation Deals
Baymont by Wyndham Santee
249 Britain Street Santee SC
$80 nightly
The price is $89 total per night from Dec 22 to Dec 23
$89 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,416 reviews)
Motel bit dated and worn. Bed was comfy, small pillows. I was surprised how quiet it was. Dog friendly and not expensive for the dog add on.
Reviewed on Dec 15, 2025
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
$70 nightly
The price is $78 total per night from Dec 22 to Dec 23
$78 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (637 reviews)
Room was clean
Reviewed on Nov 30, 2025
Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
$61 nightly
The price is $68 total per night from Jan 5 to Jan 6
$68 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7/10 Good! (678 reviews)
Clean , staff very courteous. Pet friendly!clean, friendly, on the beach, dog friendly beach area
Reviewed on Dec 11, 2025
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Santee
9125 Old Highway 6 Santee SC
$75 nightly
The price is $83 total per night from Dec 22 to Dec 23
$83 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.6/10 (440 reviews)
The staff was very friendly and helpful. Room was clean and beds were so comfortable.
Reviewed on Dec 8, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Santee
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
$70 nightly
The price is $78 total per night from Dec 22 to Dec 23
$78 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.4/10 (637 reviews)
Room was clean
Reviewed on Nov 30, 2025
Comfort Inn & Suites Santee
221 Britain St Santee SC
$105 nightly
The price is $117 total per night from Jan 4 to Jan 5
$117 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,004 reviews)
Staff was pleasant and helpful with restaurant information, room clean.
Reviewed on Dec 15, 2025
Baymont by Wyndham Santee
249 Britain Street Santee SC
$80 nightly
The price is $89 total per night from Dec 22 to Dec 23
$89 total
Dec 22 - Dec 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,416 reviews)
Motel bit dated and worn. Bed was comfy, small pillows. I was surprised how quiet it was. Dog friendly and not expensive for the dog add on.
Reviewed on Dec 15, 2025
Save an average of 15% on thousands of hotels when you're signed in
Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
$80 nightly
The price is $88 total per night from Dec 30 to Dec 31
$88 total
Dec 30 - Dec 31
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Santee Cooper Country Club and Santee ...
6.2/10 (541 reviews)
Room was clean. Staff was friendly. Bartender was great.
Reviewed on Dec 2, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Santee
Comfort Inn & Suites Santee
221 Britain St Santee SC
$105 nightly
The price is $117 total per night from Jan 4 to Jan 5
$117 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,004 reviews)
Staff was pleasant and helpful with restaurant information, room clean.
Reviewed on Dec 15, 2025
Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
$135 nightly
The price is $150 total per night from Jan 11 to Jan 12
$150 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,002 reviews)
The hotel was easy to get to and the staff was wonderful. The bed was soooo comfortable.
Reviewed on Dec 14, 2025
Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
$118 nightly
The price is $131 total per night from Dec 28 to Dec 29
$131 total
Dec 28 - Dec 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,000 reviews)
Front Desk person was very nice and helpful . Room was very clean.
Reviewed on Dec 15, 2025
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
$104 nightly
The price is $115 total per night from Dec 23 to Dec 24
$115 total
Dec 23 - Dec 24
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (975 reviews)
Yes it was
Reviewed on Dec 19, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Santee Flight and Hotel Packages
Santee flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from Newark Liberty Intl. Airport to Santee
View all tripsNeed a Car For After Your Flight?
Economy
Chevrolet Spark or similar
Compact
Ford Focus or similar
Midsize
Toyota Corolla or similar
SUV
Jeep Compass or similar
Plane Tickets To Santee
Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Santee. Browse through our inventory to explore a wide range of cheap flights to Santee to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Santee as you anxiously await to exit the plane and explore what Santee has to offer. Considering all the amazing local food and culture in Santee, we won't hold this against you.
When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santee to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santee without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santee with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santee today!
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