Cheap Flights to Orangeburg from $156

Feel at ease with free flight cancellations within 24 hours of booking

Change your flight without a fee on select flights

How Much Does it Cost To Fly To Orangeburg?

The cheapest prices found with in the last 7 days for return flights were $231 and $156 for one-way flights to Orangeburg for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
BOSWest ColumbiaJune 17 to June 30$251
DCAWest ColumbiaMay 16 to May 21$255
LGAWest ColumbiaJuly 3 to July 6$259
ORDWest ColumbiaJune 27 to July 1$269
JFKWest ColumbiaMay 29 to May 30$285
EWRWest ColumbiaMay 29 to May 30$285
BDLWest ColumbiaJune 5 to June 13$294
LAXWest ColumbiaJuly 8 to July 14$387
TTNWest ColumbiaJune 2 to June 9$388
DFWWest ColumbiaJuly 3 to July 4$447
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
DCAWest ColumbiaMay 1 to May 2$392
ORDWest ColumbiaMay 1 to May 11$412
BDLWest ColumbiaMay 1 to May 4$414
TTNWest ColumbiaMay 2 to May 9$454
JFKWest ColumbiaMay 1 to May 3$458
JFKWest ColumbiaMay 1 to May 3$458
EWRWest ColumbiaMay 1 to May 2$503
DFWWest ColumbiaMay 3 to May 4$1,025
*Prices include taxes and fees

Orangeburg Flight Information

Traveling to
Orangeburg
Lowest Price
$231
Number of Airlines Serving
Airlines Serving
Delta
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Orangeburg Accommodation Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
$80 nightly
The price is $89 total per night from May 3 to May 4
$89 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,449 reviews)
Breakfast was basic yogurt waffle maker and cereal

Reviewed on Apr 26, 2026

Opens in a new windowBaymont by Wyndham Santee
Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

2 out of 5
3620 Saint Matthews Rd Orangeburg SC
$71 nightly
The price is $79 total per night from Apr 29 to Apr 30
$79 total
Apr 29 - Apr 30
Total with taxes and fees
Stay at this motel in Orangeburg. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,005 reviews)
Wonderful stay!

Reviewed on Apr 24, 2026

Opens in a new windowTravelodge by Wyndham Orangeburg
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

2 out of 5
3608 Saint Matthews Rd Orangeburg SC
$58 nightly
The price is $64 total per night from May 3 to May 4
$64 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly motel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7/10 Good! (966 reviews)
Excellent as always,clean rooms and the staff always helpful.

Reviewed on Apr 27, 2026

Opens in a new windowSuper 8 by Wyndham, Orangeburg
Save an average of 15% on thousands of hotels when you're signed in
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from May 3 to May 4
$70 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.6/10 (653 reviews)
Staff was rude and the motel had roaches.

Reviewed on Apr 22, 2026

Opens in a new windowRed Roof Inn Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Orangeburg

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

2 out of 5
3620 Saint Matthews Rd Orangeburg SC
$71 nightly
The price is $79 total per night from Apr 29 to Apr 30
$79 total
Apr 29 - Apr 30
Total with taxes and fees
Stay at this motel in Orangeburg. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,005 reviews)
Wonderful stay!

Reviewed on Apr 24, 2026

Opens in a new windowTravelodge by Wyndham Orangeburg
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from May 3 to May 4
$70 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.6/10 (653 reviews)
Staff was rude and the motel had roaches.

Reviewed on Apr 22, 2026

Opens in a new windowRed Roof Inn Santee
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
$111 nightly
The price is $123 total per night from May 19 to May 20
$123 total
May 19 - May 20
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,004 reviews)
Parking was easy but a little cramped the hotel is currently undergoing renovation and you cannot see out of the windows this was not mentioned during booking or on there website the room was fine but could be a bit cleaner and there was no shampoo at all it was a completely empty bottle. The breakfast ...

Reviewed on Apr 26, 2026

Opens in a new windowComfort Inn & Suites Santee
Save an average of 15% on thousands of hotels when you're signed in
Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North

2.5 out of 5
3583 Saint Matthews Rd Orangeburg SC
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
6/10 (1,001 reviews)
Breakfast was very poor not what would be expected at Windham hotel Our room128 did not look lick this photo, bathroom door had been broken tub and shower should be replaced WILL NOT BOOK BAYMOUNT PROPERTY AGAIN

Reviewed on Apr 21, 2026

Opens in a new windowBaymont by Wyndham Orangeburg North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Orangeburg

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
$111 nightly
The price is $123 total per night from May 19 to May 20
$123 total
May 19 - May 20
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,004 reviews)
Parking was easy but a little cramped the hotel is currently undergoing renovation and you cannot see out of the windows this was not mentioned during booking or on there website the room was fine but could be a bit cleaner and there was no shampoo at all it was a completely empty bottle. The breakfast ...

Reviewed on Apr 26, 2026

Opens in a new windowComfort Inn & Suites Santee
Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North

2.5 out of 5
3583 Saint Matthews Rd Orangeburg SC
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Smith-Hammond-Middleton Memorial ...
6/10 (1,001 reviews)
Breakfast was very poor not what would be expected at Windham hotel Our room128 did not look lick this photo, bathroom door had been broken tub and shower should be replaced WILL NOT BOOK BAYMOUNT PROPERTY AGAIN

Reviewed on Apr 21, 2026

Opens in a new windowBaymont by Wyndham Orangeburg North
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

2.5 out of 5
731 Citadel Road Orangeburg SC
$103 nightly
The price is $115 total per night from May 3 to May 4
$115 total
May 3 - May 4
Total with taxes and fees
Book a stay at this business-friendly hotel in Orangeburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (1,005 reviews)
Had ants every where!

Reviewed on Apr 25, 2026

Opens in a new windowSpark by Hilton Orangeburg
Save an average of 15% on thousands of hotels when you're signed in
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
$119 nightly
The price is $132 total per night from May 25 to May 26
$132 total
May 25 - May 26
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,006 reviews)
The breakfast staff ladies were wonderful. They made the last moments of our stay so much nicer.

Reviewed on Apr 28, 2026

Opens in a new windowHampton Inn Santee-I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Frequently asked questions

Which airlines fly to Orangeburg?
Is Orangeburg the first stopover on your unforgettable world adventure? Wise travelers recommend booking a flight with American Airlines.
What airport is best to fly into Orangeburg?
Orangeburg has just one airport, which makes booking your flight here a simple process. CAE is about 35 mi from all the action downtown.
Where to stay in Orangeburg
Choosing a great place to stay is a key ingredient for an unforgettable travel experience. Select from 56 hotels in Orangeburg and start cooking up the vacation of your dreams!Securing accommodations can often be a little tedious. Make the process easier on yourself and check out some of our top recommendations, the Palmetto Inn & Suites and the Rodeway Inn and Suites.
Places to visit in Orangeburg
Appreciate the extensive array of artistic creations at I.P. Stanback Museum & Planetarium. This notable art museum is a fine venue to spend some time. After more options? Take a deep breath of the wonderfully fragrant air and enjoy the gorgeous floral displays at Edisto Memorial Gardens.
How to get through airport security fast when traveling to Orangeburg
Make your journey to Orangeburg a little bit easier by following these helpful tips and pointers:

  • Be sure you know the whereabouts of your boarding pass and passport. You don't want to hold up the queue when you're asked to present them.
  • Remove your shoes, belt and jewellery before approaching security. Items such as these are not allowed in the body scanner.
  • Digital cameras, laptops and other electronic devices must be placed in a bin to be X-rayed.
  • When it comes to flying with liquids or gels, each passenger is permitted a quart-sized clear resealable bag to keep containers no larger than 3.4 ounces (100 milliliters).
  • Untie your shoelaces in preparation for entering the body scanner. Depending on the sort of shoes you're wearing, security may ask you to take them off.
  • Some destinations have stringent biosecurity laws. Think about where you're journeying to and whether or not you can travel with fresh fruit and meat.

Plane Tickets To Orangeburg

Although you may try and resist the urge, you know that when the travel bug comes, there is only one way to get rid of it. Thankfully, Travelocity is here to help nip that travel bug in the bud with great deals on flights to Orangeburg. Browse through our inventory to explore a wide range of cheap flights to Orangeburg to solidify your next big trip out of town. Whether you are heading out on a business trip, exploring a place you have never been for pleasure or are bringing the family on the annual vacation, we have the perfect getaway waiting for you. In no time, you will be day dreaming of your plane landing in Orangeburg as you anxiously await to exit the plane and explore what Orangeburg has to offer. Considering all the amazing local food and culture in Orangeburg, we won't hold this against you.

When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Orangeburg to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Orangeburg without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Orangeburg with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Orangeburg today!

Explore More Ways to Travel with Travelocity

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.