Explore 7 Luxury Hotels in Orangeburg
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Best Luxury Hotels in Orangeburg
Travelodge by Wyndham Orangeburg
3620 Saint Matthews Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Jul 19 to Jul 20
$88 total
Jul 19 - Jul 20
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-out is also provided.
8.2/10 Very Good! (1,001 reviews)
"Clean comfortable no frills place to stay convenient to dining and interstate"
Reviewed on Jul 15, 2026
Comfort Inn & Suites Santee
221 Britain St Santee SC
Fully refundable
$98 nightly
The price is $109 total per night from Aug 16 to Aug 17
$109 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
8/10 Very Good! (1,000 reviews)
"Nicest staff and our second time staying when we travel to south carolina. Really good breakfast too"
Reviewed on Jul 15, 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Jul 19 to Jul 20
$89 total
Jul 19 - Jul 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
8/10 Very Good! (1,460 reviews)
"Clean room and pet friendly"
Reviewed on Jul 13, 2026
Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Aug 4 to Aug 5
$76 total
Aug 4 - Aug 5
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public ...
6.4/10 (573 reviews)
"Posted as a pillow top bed there was no pillow top. It was so hard. It was like sleeping on stone. Brown water coming out of the showerhead. Plugs didn’t fit in the sockets securely and actually fell out a couple times. There was hair on the side of the tub. Door jam was stuck. Screws coming out ..."
Reviewed on Jul 14, 2026
Econo Lodge Santee
9112 Old 6 Highway Santee SC
Fully refundable
$60 nightly
The price is $67 total per night from Aug 6 to Aug 7
$67 total
Aug 6 - Aug 7
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, luggage storage, and barbecue grills are also on offer.
6.4/10 (316 reviews)
"Pretty nice and clean with a comfortable bed at a great rate."
Reviewed on Jul 15, 2026
Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $61 total per night from Jul 26 to Jul 27
$61 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
6/10 (1,000 reviews)
"Clean room and property. Nice quick continental breakfast. Staff was nice. Convenient to the interstate. Felt completely safe here. If needed will stay again."
Reviewed on Jul 13, 2026
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $70 total per night from Jul 20 to Jul 21
$70 total
Jul 20 - Jul 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Orangeburg Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Orangeburg luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Orangeburg to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Orangeburg will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Orangeburg, and plan your next opulent escape.
Orangeburg hotels essential information
Accommodation | 254 hotels |
|---|---|
Lowest Price | $61 |
Highest Price | $109 |
Popular hotels | Travelodge by Wyndham Orangeburg, Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Orangeburg North, Baymont by Wyndham Santee, Ramada by Wyndham Santee I-95, Econo Lodge Santee |
Popular Luxury Stays in Orangeburg
Recent Orangeburg Hotel Reviews By Fellow Wanderers
Travelodge by Wyndham Orangeburg
4 out of 5
Posted 15 hours ago
Travelocity Verified Review
"Clean comfortable no frills place to stay convenient to dining and interstate"
A verified traveler stayed at Travelodge by Wyndham Orangeburg
Baymont by Wyndham Orangeburg North
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Clean room and property. Nice quick continental breakfast. Staff was nice. Convenient to the interstate. Felt completely safe here. If needed will stay again."
A verified traveler stayed at Baymont by Wyndham Orangeburg North
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