Explore 7 Luxury Hotels in Orangeburg

Name: Baymont by Wyndham Orangeburg North
Price range: $61 total
Rating: 5.8

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Best Luxury Hotels in Orangeburg

Travelodge by Wyndham Orangeburg

3620 Saint Matthews Rd Orangeburg SC

Fully refundableReserve now, pay when you stay

$79 nightly

$88 total

Jan 6 - Jan 7

Total with taxes and fees

Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-out is also provided.

8/10 Very Good! (1,002 reviews)

We were greeted at the reception desk by gentleman who genuinely was happy to see us... That normally doesn't happen.. The bed was very comfortable and that was the most important thing. We didn't shower. We just jumped back in the car and continued on to our destination so we did not take advantage ...

Reviewed on Dec 25, 2025

Comfort Inn & Suites Santee

221 Britain St Santee SC

Fully refundableReserve now, pay when you stay

$105 nightly

$117 total

Jan 12 - Jan 13

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...

8/10 Very Good! (1,012 reviews)

All good. Bed a little hard

Reviewed on Dec 30, 2025

Baymont by Wyndham Santee

249 Britain Street Santee SC

Fully refundableReserve now, pay when you stay

$75 nightly

$83 total

Jan 6 - Jan 7

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...

7.8/10 Good! (1,419 reviews)

Staff, Latoya at the front desk was ama I ng.

Reviewed on Jan 2, 2026

Red Roof Inn Santee

9091 Old Hwy 6 Santee SC

Fully refundableReserve now, pay when you stay

$70 nightly

$78 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

6.4/10 (640 reviews)

A good option if traveling with pets. The hotel is clean and well maintained but dated.

Reviewed on Dec 21, 2025

Econo Lodge

9112 Old 6 Highway Santee SC

Fully refundableReserve now, pay when you stay

$63 nightly

$70 total

Jan 18 - Jan 19

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, luggage storage, and barbecue grills are also on offer.

6.4/10 (309 reviews)

Friendly efficient staff

Reviewed on Dec 29, 2025

Ramada by Wyndham Santee I-95

123 Mall Street Santee SC

Fully refundableReserve now, pay when you stay

$79 nightly

$87 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

6.2/10 (546 reviews)

It was awesome

Reviewed on Dec 27, 2025

Baymont by Wyndham Orangeburg North

3583 Saint Matthews Rd Orangeburg SC

Fully refundableReserve now, pay when you stay

$55 nightly

$61 total

Jan 11 - Jan 12

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...

5.8/10 (1,001 reviews)

The room was clean and the staff was great. We didn't do the breakfast because we didn't care for any thing they had

Reviewed on Dec 2, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Orangeburg Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Orangeburg luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Orangeburg to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Orangeburg will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Orangeburg, and plan your next opulent escape.

Orangeburg hotels essential information

Accommodation	257 hotels
Lowest Price	$61
Highest Price	$117
Popular hotels	Travelodge by Wyndham Orangeburg, Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Orangeburg North, Baymont by Wyndham Santee, Ramada by Wyndham Santee I-95, Econo Lodge

Popular Luxury Stays in Orangeburg

Recent Orangeburg Hotel Reviews By Fellow Wanderers

Travelodge by Wyndham Orangeburg

5 out of 5

Posted 10 days ago

Travelocity Verified Review

"We were greeted at the reception desk by gentleman who genuinely was happy to see us... That normally doesn't happen.. The bed was very comfortable and that was the most important thing. We didn't shower. We just jumped back in the car and continued on to our destination so we did not take advantage of all the accommodations.. We will stay there on our way back home after our vacation.."

A verified traveler stayed at Travelodge by Wyndham Orangeburg