Explore 7 Luxury Hotels in Orangeburg

Name: Baymont by Wyndham Orangeburg North
Price range: $67 total
Rating: 6

Best Luxury Hotels in Orangeburg

Travelodge by Wyndham Orangeburg

3620 Saint Matthews Rd, Orangeburg, SC

Fully refundableReserve now, pay when you stay

$71 nightly

$79 total

Aug 24 - Aug 25

Total with taxes and fees

Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-out is also provided.

8/10 Very Good! (1,000 reviews)

"Clean room, comfortable bed, staff was welcoming"

Reviewed on Jul 27, 2025

Comfort Inn & Suites Santee

221 Britain St, Santee, SC

Fully refundableReserve now, pay when you stay

$101 nightly

$112 total

Aug 28 - Aug 29

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...

7.8/10 Good! (1,000 reviews)

"Clean with a good breakfast."

Reviewed on Aug 14, 2025

Baymont by Wyndham Santee

249 Britain Street, Santee, SC

Fully refundableReserve now, pay when you stay

$75 nightly

$83 total

Aug 24 - Aug 25

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...

7.8/10 Good! (1,329 reviews)

"The front desk lady was fantastic! So helpful when it came to finding a place to grab a quick bite to eat. The property itself was very lovely. It was clean and updated with a touch of old school motel feel."

Reviewed on Aug 19, 2025

Red Roof Inn Santee

9091 Old Hwy 6, Santee, SC

Fully refundableReserve now, pay when you stay

$62 nightly

$69 total

Aug 24 - Aug 25

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

6.4/10 (621 reviews)

"Great"

Reviewed on Jun 20, 2025

Ramada by Wyndham Santee I-95

123 Mall Street, Santee, SC

Fully refundableReserve now, pay when you stay

$78 nightly

$87 total

Aug 28 - Aug 29

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

6.2/10 (533 reviews)

"Pool was nice and clean."

Reviewed on Aug 9, 2025

Econo Lodge

9112 Old 6 Highway, Santee, SC

Fully refundableReserve now, pay when you stay

$61 nightly

$68 total

Sep 4 - Sep 5

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, luggage storage, and barbecue grills are also on offer.

6.2/10 (308 reviews)

"Clean room. No issues with late check"

Reviewed on Jun 5, 2025

Baymont by Wyndham Orangeburg North

3583 Saint Matthews Rd, Orangeburg, SC

Fully refundableReserve now, pay when you stay

$60 nightly

$67 total

Aug 24 - Aug 25

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...

6/10 (1,001 reviews)

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Reviewed on Jul 30, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Orangeburg Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Orangeburg luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Orangeburg to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Orangeburg will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Orangeburg, and plan your next opulent escape.

Orangeburg hotels essential information

Accommodation	237 hotels
Lowest Price	$67
Highest Price	$112
Popular hotels	Travelodge by Wyndham Orangeburg, Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Orangeburg North, Baymont by Wyndham Santee, Ramada by Wyndham Santee I-95, Econo Lodge