Explore 7 Luxury Hotels in Orangeburg

Name: Baymont by Wyndham Orangeburg North
Price range: $61 total
Rating: 6

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Best Luxury Hotels in Orangeburg

Travelodge by Wyndham Orangeburg

3620 Saint Matthews Rd Orangeburg SC

Fully refundableReserve now, pay when you stay

$67 nightly

$75 total

Dec 1 - Dec 2

Total with taxes and fees

Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-out is also provided.

8/10 Very Good! (1,004 reviews)

Not much offered for breakfast.

Reviewed on Nov 16, 2025

Comfort Inn & Suites Santee

221 Britain St Santee SC

Fully refundableReserve now, pay when you stay

$99 nightly

$109 total

Dec 7 - Dec 8

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...

8/10 Very Good! (1,001 reviews)

Everything was what we expected.

Reviewed on Nov 13, 2025

Baymont by Wyndham Santee

249 Britain Street Santee SC

Fully refundableReserve now, pay when you stay

$80 nightly

$89 total

Nov 23 - Nov 24

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...

7.8/10 Good! (1,395 reviews)

Clean and upgraded

Reviewed on Nov 15, 2025

Red Roof Inn Santee

9091 Old Hwy 6 Santee SC

Fully refundableReserve now, pay when you stay

$63 nightly

$70 total

Nov 23 - Nov 24

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

6.4/10 (635 reviews)

It's a good stop for the price

Reviewed on Nov 14, 2025

Ramada by Wyndham Santee I-95

123 Mall Street Santee SC

Fully refundableReserve now, pay when you stay

$70 nightly

$77 total

Dec 4 - Dec 5

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

6.2/10 (540 reviews)

Room was clean, and quiet. Staff at the bar/restaurant was friendly.

Reviewed on Nov 11, 2025

Econo Lodge

9112 Old 6 Highway Santee SC

Fully refundableReserve now, pay when you stay

$57 nightly

$64 total

Dec 4 - Dec 5

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, luggage storage, and barbecue grills are also on offer.

6.2/10 (308 reviews)

Clean room. No issues with late check

Reviewed on Jun 5, 2025

Baymont by Wyndham Orangeburg North

3583 Saint Matthews Rd Orangeburg SC

Fully refundableReserve now, pay when you stay

$55 nightly

$61 total

Dec 7 - Dec 8

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...

6/10 (1,002 reviews)

clean room, great staff

Reviewed on Nov 10, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Orangeburg Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Orangeburg luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Orangeburg to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Orangeburg will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Orangeburg, and plan your next opulent escape.

Orangeburg hotels essential information

Accommodation	256 hotels
Lowest Price	$61
Highest Price	$109
Popular hotels	Travelodge by Wyndham Orangeburg, Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Orangeburg North, Baymont by Wyndham Santee, Ramada by Wyndham Santee I-95, Econo Lodge