Explore 7 Luxury Hotels in Orangeburg
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Best Luxury Hotels in Orangeburg
Travelodge by Wyndham Orangeburg
3620 Saint Matthews Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $88 total per night from Apr 15 to Apr 16
$88 total
Apr 15 - Apr 16
Total with taxes and fees
Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-out is also provided.
8.2/10 Very Good! (1,008 reviews)
Easy parking basic cereal breakfast. Room was clean. Was a lot of traffic noise loud vehicles racing on streets. Served its purpose for a nights rest.
Reviewed on Apr 14, 2026
Comfort Inn & Suites Santee
221 Britain St Santee SC
Fully refundable
$110 nightly
The price is $122 total per night from May 10 to May 11
$122 total
May 10 - May 11
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...
8/10 Very Good! (1,011 reviews)
Great staff.
Reviewed on Apr 13, 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $89 total per night from Apr 15 to Apr 16
$89 total
Apr 15 - Apr 16
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...
8/10 Very Good! (1,446 reviews)
Breakfast is always good, I’ve stay at Baymont about 6 times and it’s always been very good!
Reviewed on Apr 13, 2026
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Apr 20 to Apr 21
$68 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
6.6/10 (650 reviews)
The check in lady was uncooperative & unhelpful. Only 1 towel for each person. Would not recommend.
Reviewed on Apr 9, 2026
Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $86 total per night from Apr 15 to Apr 16
$86 total
Apr 15 - Apr 16
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this hotel. Traveling on business? Take advantage of the business center, free WiFi in public ...
6.4/10 (554 reviews)
Great!!!
Reviewed on Apr 12, 2026
Econo Lodge Santee
9112 Old 6 Highway Santee SC
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $75 total per night from May 7 to May 8
$75 total
May 7 - May 8
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, luggage storage, and barbecue grills are also on offer.
6.4/10 (312 reviews)
Very clean room, fast staff, a lot of food spots nearby!
Reviewed on Mar 24, 2026
Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $64 total per night from Apr 26 to Apr 27
$64 total
Apr 26 - Apr 27
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
6/10 (1,006 reviews)
Nice, very comfortable beds, and large parking lot that accommodates very large box trucks
Reviewed on Apr 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Orangeburg Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Orangeburg luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in Orangeburg to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in Orangeburg will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Orangeburg, and plan your next opulent escape.
Orangeburg hotels essential information
Accommodation | 253 hotels |
|---|---|
Lowest Price | $64 |
Highest Price | $122 |
Popular hotels | Travelodge by Wyndham Orangeburg, Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Orangeburg North, Baymont by Wyndham Santee, Ramada by Wyndham Santee I-95, Econo Lodge Santee |
Popular Luxury Stays in Orangeburg
Recent Orangeburg Hotel Reviews By Fellow Wanderers
Travelodge by Wyndham Orangeburg
3 out of 5
Posted 8 hours ago
Travelocity Verified Review
"Easy parking basic cereal breakfast. Room was clean. Was a lot of traffic noise loud vehicles racing on streets. Served its purpose for a nights rest."
A verified traveler stayed at Travelodge by Wyndham Orangeburg
Baymont by Wyndham Orangeburg North
5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"Nice, very comfortable beds, and large parking lot that accommodates very large box trucks "
A verified traveler stayed at Baymont by Wyndham Orangeburg North
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