Explore 7 Luxury Hotels in Orangeburg

Name: Baymont by Wyndham Orangeburg North
Price range: $72 total
Rating: 6

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Best Luxury Hotels in Orangeburg

Travelodge by Wyndham Orangeburg

3620 Saint Matthews Rd, Orangeburg, SC

Fully refundableReserve now, pay when you stay

$89 nightly

$99 total

Oct 7 - Oct 8

Total with taxes and fees

Free self parking is available and the motel's front desk is staffed around-the-clock. WiFi in public areas is free. Express check-out is also provided.

8/10 Very Good! (1,000 reviews)

"Clean room, however the wall where the shower curtain rod attaches need plaster and paint. Also, the ceiling in the corner over the shower head has a small hole in the ceiling where it is missing plaster and paint."

Reviewed on Sep 28, 2025

Comfort Inn & Suites Santee

221 Britain St, Santee, SC

Fully refundableReserve now, pay when you stay

$105 nightly

$117 total

Oct 12 - Oct 13

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. ...

8/10 Very Good! (1,000 reviews)

Nice mid trip stop

"Lobby and dining area were very clean. Our room was a little dated but clean and well kept. The staff were also all very friendly and helpful.We only stayed 1 night as it was a stopping point for a longer trip."

Reviewed on Sep 5, 2025

Baymont by Wyndham Santee

249 Britain Street, Santee, SC

Fully refundableReserve now, pay when you stay

$75 nightly

$83 total

Oct 7 - Oct 8

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of ...

7.8/10 Good! (1,349 reviews)

"Didn’t see the pet areas"

Reviewed on Oct 3, 2025

Red Roof Inn Santee

9091 Old Hwy 6, Santee, SC

Fully refundableReserve now, pay when you stay

$70 nightly

$78 total

Nov 3 - Nov 4

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...

6.4/10 (627 reviews)

"Despite offering breakfast, it was lackluster"

Reviewed on Aug 23, 2025

Ramada by Wyndham Santee I-95

123 Mall Street, Santee, SC

Fully refundableReserve now, pay when you stay

$71 nightly

$79 total

Oct 8 - Oct 9

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

6.2/10 (537 reviews)

"The grounds and property were clean and you could tell they take pride in what they're offering."

Reviewed on Sep 9, 2025

Econo Lodge

9112 Old 6 Highway, Santee, SC

Fully refundableReserve now, pay when you stay

$59 nightly

$66 total

Nov 3 - Nov 4

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, luggage storage, and barbecue grills are also on offer.

6.2/10 (308 reviews)

"Clean room. No issues with late check"

Reviewed on Jun 5, 2025

Baymont by Wyndham Orangeburg North

3583 Saint Matthews Rd, Orangeburg, SC

Fully refundableReserve now, pay when you stay

$65 nightly

$72 total

Oct 7 - Oct 8

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...

6/10 (1,003 reviews)

"Bed was clean and comfortable. The bathroom had some damage like broken door and cracked tile but otherwise was clean and everything worked."

Reviewed on Sep 30, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Orangeburg Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Orangeburg luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Orangeburg to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Orangeburg will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Orangeburg, and plan your next opulent escape.

Orangeburg hotels essential information

Accommodation	239 hotels
Lowest Price	$66
Highest Price	$117
Popular hotels	Travelodge by Wyndham Orangeburg, Red Roof Inn Santee, Comfort Inn & Suites Santee, Baymont by Wyndham Orangeburg North, Baymont by Wyndham Santee, Ramada by Wyndham Santee I-95, Econo Lodge