Santee Vacation Packages 2026 from $628

Santee flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Country Inn & Suites by Radisson, Columbia Airport, SC

$628

per person

Nov 23 - Nov 26

found 1 day ago

Roundtrip non-stop flight included

New York (JFK) to Columbia (CAE)

This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Guests will appreciate freebies like continental breakfast and free self parking.

Fairfield Inn and Suites by Marriott Columbia

$706

per person

Oct 27 - Oct 30

found 1 day ago

Roundtrip non-stop flight included

St. Louis (STL) to Columbia (CAE)

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the free buffet breakfast each morning.

Courtyard by Marriott Columbia Cayce

$772

per person

Oct 27 - Oct 30

found 1 day ago

Roundtrip non-stop flight included

St. Louis (STL) to Columbia (CAE)

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the 24-hour gym and perks like free self parking.

The Garnet Goliath

$1,150

per person

Oct 27 - Oct 30

found 1 day ago

Roundtrip non-stop flight included

St. Louis (STL) to Columbia (CAE)

This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden and laundry facilities are also provided.

Hilton Columbia Center

Downtown Columbia

$933

per person

Oct 27 - Oct 29

found 13 hours ago

Roundtrip flight included

Chicago (CHI) to Columbia (CAE)

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a 24-hour gym on site, and laundry facilities and concierge services are also offered.

Top Santee hotels deals

Tru By Hilton Santee

263 Britain St. and 273 Britain St. Santee SC

Free Cancellation

Reserve now, pay when you stay

$108 total

per night

Sep 27 - Sep 28

This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.

Baymont by Wyndham Santee

249 Britain Street Santee SC

Free Cancellation

Reserve now, pay when you stay

$89 total

per night

Sep 22 - Sep 23

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express check-in and free internet in public areas. There's express check-out and multilingual staff can provide around-the-clock assistance.

Breakfast included

Pet friendly

Fairfield Inn & Suites by Marriott Santee

9074 Old Number Six Hwy Santee SC

Free Cancellation

Reserve now, pay when you stay

$149 total

per night

Sep 27 - Sep 28

This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a snack bar/deli, and a picnic area are also on offer.

Pool

Breakfast included

Comfort Inn & Suites Santee

221 Britain St Santee SC

Free Cancellation

$118 total

per night

Sep 27 - Sep 28

This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a lobby fireplace, and laundry facilities are also on offer.

Hampton Inn Santee-I-95

9060 Old Number Six Hwy Santee SC

Free Cancellation

Reserve now, pay when you stay

$139 total

per night

Sep 27 - Sep 28

This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, a terrace, and laundry facilities are also on offer.

Pool

Breakfast included

Best Western Plus Santee Inn

I 95 Exit 98 Santee SC

Free Cancellation

Reserve now, pay when you stay

$127 total

per night

Sep 27 - Sep 28

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santee attractions

Santee State Park

8.0/10 (219 reviews)

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.

See properties

Frequently asked questions

How much are vacation packages to Santee?

With vacation packages available from as little as $628, it's not necessary to drain your bank balance for your getaway to Santee. Travelocity can help. Bundle your hotels, flights and tours into a package and walk away with fantastic discounts. The more you book, the more you save.

How long should my Santee vacation be?

Most visitors stay in Santee for approximately 2 nights. That said, travel is all about trying out new things and making memories — why not stay a couple of extra nights so you can do just that?

Where can I get the best vacation package deals for Santee?

One word — Travelocity. With as many as 400 air carriers and 1,000,000 properties worldwide, it's easy to find a Santee package deal that suits your needs.

Why should I book my Santee vacation bundle via Travelocity?

Whether you're planning a month-long vacation or a last-minute trip, we have many alluring destinations to choose from at an affordable price. And on top of that, we offer support 24/7, superb service and a Price Match Guarantee. Save yourself the effort and time and book your dream vacation today.

Can I save on my Santee car rental if I combine it with my hotel or flight?

You sure can with our Santee vacation packages. With one of these, there are lots of ways to make your travel budget go further. Combine any two or more car, hotel, flight and tour bookings and watch your savings grow. With a rental car, all the popular attractions around Santee are an unforgettable road trip away.

What is there to do in Santee?

Santee is full of places to explore, such as Santee State Park and Santee Cooper Country Club. These two popular attractions are on most travelers' itineraries.

Where should I stay when visiting Santee?

The Baymont by Wyndham Santee is the number one choice of many visitors. Book soon before it's too late.