Santee Vacation Packages 2026 from $445

Santee flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Sleep Inn Columbia

Seven Oaks

$445

per person

Mar 24 - Mar 27

found 22 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the business center, express check-in, and conference space. There's a gym on site, and a 24-hour front desk and a snack bar/deli are also provided.

Graduate by Hilton Columbia SC

Downtown Columbia

$619

per person

Mar 24 - Mar 27

found 22 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Self parking, a terrace, and a lobby fireplace are also offered.

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

$543

per person

Mar 24 - Mar 27

found 22 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This hotel doesn't skimp on freebies - guests receive free full breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour business center. There's a gym on site, and a 24-hour front desk and express check-in are also provided.

The Lantern Columbia

Downtown Columbia

$586

per person

Mar 24 - Mar 27

found 22 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a lobby fireplace, and a communal living room are also offered.

Chesnut Cottage Inn Bed & Breakfast

Downtown Columbia

$836

per person

Mar 24 - Mar 27

found 22 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Columbia (CAE)

This bed & breakfast features free WiFi in public areas, wedding services, and free self parking. Enjoy the free full breakfast each morning. A communal living room and a library are also provided.

Top Santee hotels deals

Tru By Hilton Santee

263 Britain St. and 273 Britain St. Santee SC

Free Cancellation

Reserve now, pay when you stay

$108 nightly

$120 total

Jan 26 - Jan 27

Total with taxes and fees

This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.

Baymont by Wyndham Santee

249 Britain Street Santee SC

Free Cancellation

Reserve now, pay when you stay

$75 nightly

$83 total

Jan 15 - Jan 16

Total with taxes and fees

This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express check-in and free internet in public areas. There's express check-out and multilingual staff can provide around-the-clock assistance.

Breakfast included

Pet friendly

Hampton Inn Santee-I-95

9060 Old Number Six Hwy Santee SC

Free Cancellation

Reserve now, pay when you stay

$129 nightly

$143 total

Jan 25 - Jan 26

Total with taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, a terrace, and laundry facilities are also on offer.

Fairfield Inn & Suites by Marriott Santee

9074 Old Number Six Hwy Santee SC

Free Cancellation

Reserve now, pay when you stay

$121 nightly

$134 total

Jan 21 - Jan 22

Total with taxes and fees

This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a snack bar/deli, and a picnic area are also on offer.

Pool

Breakfast included

Comfort Inn & Suites Santee

221 Britain St Santee SC

Free Cancellation

Reserve now, pay when you stay

$103 nightly

$114 total

Jan 21 - Jan 22

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a lobby fireplace, and laundry facilities are also on offer.

Pool

Breakfast included

Best Western Plus Santee Inn

I 95 Exit 98 Santee SC

Free Cancellation

Reserve now, pay when you stay

$118 nightly

$131 total

Jan 21 - Jan 22

Total with taxes and fees

This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Santee State Park

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.

Santee Cooper Country Club

Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.

Santee National Golf Club

Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.

Frequently asked questions

How much are vacation packages to Santee?

With vacation packages available from as little as $445, it's not necessary to drain your bank balance for your getaway to Santee. Travelocity can help. Bundle your hotels, flights and tours into a package and walk away with fantastic discounts. The more you book, the more you save.

How long should my Santee vacation be?

Most visitors stay in Santee for approximately 2 nights. That said, travel is all about trying out new things and making memories — why not stay a couple of extra nights so you can do just that?

Where can I get the best vacation package deals for Santee?

One word — Travelocity. With as many as 400 air carriers and 1,000,000 properties worldwide, it's easy to find a Santee package deal that suits your needs.

Why should I book my Santee vacation bundle via Travelocity?

Whether you're planning a month-long vacation or a last-minute trip, we have many alluring destinations to choose from at an affordable price. And on top of that, we offer support 24/7, superb service and a Price Match Guarantee. Save yourself the effort and time and book your dream vacation today.

Can I save on my Santee car rental if I combine it with my hotel or flight?

You sure can with our Santee vacation packages. With one of these, there are lots of ways to make your travel budget go further. Combine any two or more car, hotel, flight and tour bookings and watch your savings grow. With a rental car, all the popular attractions around Santee are an unforgettable road trip away.

What is there to do in Santee?

Santee is full of places to explore, such as Santee State Park and Santee Cooper Country Club. These two popular attractions are on most travelers' itineraries.

Where should I stay when visiting Santee?

The Baymont by Wyndham Santee is the number one choice of many visitors. Book soon before it's too late.