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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
3-star hotel near Duke University

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Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

Courtyard
Lobby
Exterior
Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace
Full-size fridge, microwave, stovetop, dishwasher

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Parking available
  • Bar
  • Kitchen
  • Pet friendly
  • Housekeeping

Explore the area

View in a map
1108 West Main Street, Durham, NC, 27701
  • Duke University
    ‪3 min walk‬
  • Durham Performing Arts Center
    ‪17 min walk‬
  • Duke University Hospital
    ‪2 min drive‬
  • Raleigh, NC (RDU-Raleigh - Durham Intl.)
    ‪20 min drive‬

Room options

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

9.2 out of 10
Wonderful
(5 reviews)
  • 469 sq ft
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

  • 478 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed, Non Smoking

8.8 out of 10
Excellent
(31 reviews)
  • 480 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

  • 479 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

10.0 out of 10
Exceptional
(2 reviews)
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub) | 1 bedroom, in-room safe, desk, laptop workspace

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

  • 479 sq ft
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed, Non Smoking

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed, Non Smoking

9.6 out of 10
Exceptional
(14 reviews)
  • 424 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

1 bedroom, in-room safe, desk, laptop workspace

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

  • 426 sq ft
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

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About the neighborhood

Durham

Downtown Durham stay.Within a 10-minute walk of this Downtown Durham hotel, you'll find Duke University and Brightleaf Square. Carolina Theatre and Durham Convention Center are also within half a mile (1 km).

What's nearby

  • Duke University - 3 min walk - 0.2 miles
  • Durham Bulls Athletic Park - 16 min walk - 0.9 miles
  • Durham Performing Arts Center - 17 min walk - 0.9 miles
  • Duke University Hospital - 2 min drive - 1.7 miles
  • Cameron Indoor Stadium - 6 min drive - 2.5 miles

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 19 min drive

Restaurants

  • ‪Atomic Clock Brewing Co - ‬11 min walk
  • ‪The Can Opener - ‬7 min walk
  • ‪Fonda Lupita - ‬3 min walk
  • ‪Ramblers - ‬7 min walk
  • ‪Emmy Squared - ‬5 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

3-star hotel near Duke University
You can enjoy a drink at the bar/lounge. Free breakfast is available daily. A computer station is on site and WiFi is free in public spaces.

There's an onsite business center. Event space at this hotel measures 2530 square feet (235 square meters) and includes conference space. A 24-hour fitness center, a terrace, and coffee/tea in a common area are also featured at the business-friendly Residence Inn Durham McPherson/Duke University Medical Cntr. Parking is available for a fee. A complete renovation of Residence Inn Durham McPherson/Duke University Medical Cntr was completed in April 2024.

This 3-star Durham hotel is smoke free.

  • 147 guestrooms or units
  • 5 levels
  • 2530 sq ft of conference space
  • 235 sq m of conference space
  • Built in 2015
  • To-go breakfast (free)
  • Business facilities
  • Conference space
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-in
  • Express check-out
  • Storage area for luggage
  • Front-desk safe
  • Concierge
  • Grocery service (free)
  • Wedding services available
  • Convenience store
  • Terrace
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Elevator
  • No smoking on site
  • Bar or lounge
Residence Inn Durham McPherson/Duke University Medical Cntr offers 147 accommodations with safes and coffee/tea makers. Accommodations offer separate sitting areas and include dining tables. 32-inch Smart televisions come with premium cable channels, pay movies, and Netflix. Accommodations at this 3-star hotel have kitchens with full-sized refrigerators/freezers, stovetops, microwaves, and cookware/dishes/utensils. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers.

This Durham hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

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Home2 Suites By Hilton Durham University Medical Center

  • Pool
  • Breakfast included
  • Pet friendly
  • Parking included
4.9 out of 5, Exceptional, 227 reviews
$127 nightly
The price is $144
Sep 21 - Sep 22
Total with taxes and fees
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Property amenities

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free area shuttle
  • Self parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • A bar/lounge
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Hardwood flooring in room
  • Lever door handles
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible registration desk (34 inches high)
  • Wheelchair-accessible restaurant

Room amenities

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay movies

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Kitchen
  • Microwave
  • Stovetop

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Energy-saving switches in guestrooms
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; Check-in end time: midnight
Express check-in available
Minimum check-in age: 21

Check-out

Check-out before noon
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100.00 per pet (varies based on length of stay)
  • Maximum 2 (weight limit: 100 lbs per pet)
  • Restrictions apply
  • For more information, you can reach out to the property at the number on the booking confirmation
  • Service animals are exempt from fees

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cribs (infant beds) are not available.

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Self parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Union Pay. Cash is not accepted. For guests' safety, the property includes a carbon monoxide detector and a smoke detector in each accommodation. This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott).

We should mention

  • To make arrangements to bring your pet, contact the property directly at the number on your booking confirmation (please see the Fees section for related charges).
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

How close is Residence Inn Durham McPherson/Duke University Medical Cntr to the airport?

Residence Inn Durham McPherson/Duke University Medical Cntr is 15 mi (19-min drive) away from the Raleigh-Durham International Airport (RDU) airport, the closest popular airport to the property.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of Sep 4, 2025, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on Oct 5, 2025 start from $148.86, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Residence Inn Durham McPherson/Duke University Medical Cntr have an airport shuttle?

Airport shuttle services are not available at Residence Inn Durham McPherson/Duke University Medical Cntr.

Does Residence Inn Durham McPherson/Duke University Medical Cntr offer free breakfast?

Residence Inn Durham McPherson/Duke University Medical Cntr offers free on-the-go breakfast every day from 7:00 AM to 9:00 AM.

Is there a casino at Residence Inn Durham McPherson/Duke University Medical Cntr?

No, there is no casino at this hotel.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; Check-in end time: midnight.

Is there free parking at Residence Inn Durham McPherson/Duke University Medical Cntr?

Free parking is not available at this hotel. Self parking is available for USD 15 per day.

Does Residence Inn Durham McPherson/Duke University Medical Cntr have a pool?

Residence Inn Durham McPherson/Duke University Medical Cntr does not have a pool.

Does Residence Inn Durham McPherson/Duke University Medical Cntr have a spa?

There are no spa services available at this hotel.

How close is Residence Inn Durham McPherson/Duke University Medical Cntr to downtown Durham?

Residence Inn Durham McPherson/Duke University Medical Cntr is 0.7 mi away from Durham.

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 306 out of 446 reviews
Rating 8 - Good. 101 out of 446 reviews
Rating 6 - Okay. 25 out of 446 reviews
Rating 4 - Poor. 6 out of 446 reviews
Rating 2 - Terrible. 8 out of 446 reviews

9.4/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.4/10

Property conditions & facilities

9.0/10

Eco-friendliness

Reviews

10/10 Excellent

Daneen

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

10/10 Excellent

David

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We love staying here when we come to visit our family. Every stay has been wonderful. The room is very comfortable. We love the gym and the breakfasts. Having a nice laundry area on the premises is also a huge plus. The best part is the fantastic staff-everyone is so nice and helpful. Thank you for always making our trips memorable.
Stayed 7 nights in May 2025

6/10 Okay

Tian

Traveled with family
Disliked: Staff & service, amenities
It smelled musky and like urine in our room and much of the facility just smelled like cleaning supplies. The wifi wasn’t great in the room. The location is decently close to Duke, but the immediate area is at a street intersection right by a gas station. There was plenty of parking for pay by mobile 15$.
Stayed 1 night in May 2025

10/10 Excellent

douglas

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

10/10 Excellent

Reed

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place to stay if you have business at Duke. Housekeeping is hit-or-miss, but that's par for the course for an extended-stay hotel.
Stayed 6 nights in Apr 2025

10/10 Excellent

Andrea

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

10/10 Excellent

Verified traveler

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great value, good location, decent breakfast

Clean, walking distance to gas stations and restaurants.,, decent breakfast in the morning that was free so can't complain... free hot coffee all day... spacious and well-decorated rooms with good cable and smart tvs. All around, great value for the price
Stayed 2 nights in Jan 2025

10/10 Excellent

chantal

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025

10/10 Excellent

Kenneth, Virginia Beach

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Jan 2025

8/10 Good

Minor, Greenville

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025

8/10 Good

Irina

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Peter

Stayed 1 night in Jan 2025

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Nov 2024

10/10 Excellent

Cynthia

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Loved Tiffani. Beautiful facility.

The hotel was beautiful, conveniently octane the suite was immaculate. The receptionist,Tiffani, was kind and charming, a great representative of your company.
Stayed 1 night in Dec 2024

10/10 Excellent

Swarup

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stuffs are nice!
Stayed 1 night in Dec 2024

10/10 Excellent

George B

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Dec 2024

10/10 Excellent

Tara, New York

Stayed 3 nights in Aug 2024

10/10 Excellent

robert

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Dec 2024

10/10 Excellent

Alan

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Dec 2024

2/10 Terrible

Michael

Disliked: Cleanliness, staff & service, property conditions & facilities, room comfort

Long drive to have my room given away.

After confirming my stay with the Residence Inn Durham by checking in online, then email exchange just hours before my arrival stating “I am on my way and would be there in 2hrs”- then the hotel acknowledging that check in… I got to the front desk at 6:10pm to find out I no longer had a room and was being re-booked at a different, lesser quality hotel 10 mins away. (After driving 9hrs to get there). Utterly ridiculous and I’ll never book a room with them again.
Stayed 1 night in Dec 2024

8/10 Good

Garth

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 6 nights in Nov 2024

2/10 Terrible

Ligenia

Disliked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2024

8/10 Good

Suzanne

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Overall this was a good place to stay for an extended trip. The staff was very helpful and the rooms were very clean. As a pet friendly place, this was a plus. Our only complaint was the included breakfast buffet which was uniformly terrible each day. But, with a kitchen in the suite it did not really matter.
Stayed 6 nights in Nov 2024

10/10 Excellent

Pebe

Business traveler, Traveled with family
Liked: Staff & service, amenities, property conditions & facilities
Stayed 1 night in Nov 2024