Book Hotels in Northeast Missouri, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Northeast Missouri hotels
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Feb 19 to Feb 20
$106 total
Feb 19 - Feb 20
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Clean room. Great staff.
Reviewed on Feb 12, 2026
Live by Loews - St.Louis
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Feb 16 to Feb 17
$177 total
Feb 16 - Feb 17
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Great views, friendly staff, clean rooms, everything you need is right there for you. Room service was convenient and walking distance to fun restaurants and city life
Reviewed on Feb 9, 2026
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Feb 22 to Feb 23
$162 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Everything was superlative. Staff, hotel, room, pool.
Reviewed on Feb 11, 2026
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $119 total per night from Feb 22 to Feb 23
$119 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
Considering the price I wasn’t expecting such a nice place, from the entrance, to the easy parking, to the amazing breakfast… everything was so great and I would 1000% consider this place for my future stays in St. Louis! The staff was also very helpful and friendly!
Reviewed on Feb 12, 2026
Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $110 total per night from Feb 19 to Feb 20
$110 total
Feb 19 - Feb 20
Total with taxes and fees
This hotel features an indoor pool, a hot tub, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
The room was terrific, loved the hot tub, drinks, snacks, and the Coke bar.
Reviewed on Feb 11, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $117 total per night from Mar 9 to Mar 10
$117 total
Mar 9 - Mar 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
Zero complaints! Enjoyed our stay and will stay again!
Reviewed on Feb 15, 2026
The Westin St. Louis
811 Spruce St St. Louis MO
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $148 total per night from Feb 22 to Feb 23
$148 total
Feb 22 - Feb 23
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling on business? Take advantage of the business center, express check-in, and valet parking. ...
The room was amazing! Very spacious & the beds were very comfortable. The bathtub was perfect for soaking after a long day of sports. Let’s all talk about Orlando…the best valet/staff member there. He was so friendly & helpful. We will for sure be staying here again.
Reviewed on Feb 11, 2026
Marriott St. Louis Grand
800 Washington Ave St. Louis MO
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $181 total per night from Mar 9 to Mar 10
$181 total
Mar 9 - Mar 10
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Room was very nice. Beds super comfy. Hotel lobby provided a great space to gather with friends.
Reviewed on Feb 5, 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $103 total per night from Feb 16 to Feb 17
$103 total
Feb 16 - Feb 17
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Coffee!! And the breakfast. Both were fantastic! Room was clean and nice except for the heating. Didn’t get much sleep due to a very noisy heating unit. Friendly people at check in and out.
Reviewed on Feb 8, 2026
Don't see what you're looking for?
See all available properties in Northeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Northeast Missouri hotels
Quality Inn St. Louis Airport Hotel
10232 Natural Bridge Rd St. Louis MO
$51 nightly
The price is $60 total per night from Feb 22 to Feb 23
$60 total
Feb 22 - Feb 23
Total with taxes and fees
6/10 (1,000 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Northeast Missouri with star-rating
Check Northeast Missouri Hotels by Star Rating
5 Star Hotels
1 properties
Recent Northeast Missouri hotel reviews by fellow wanderers
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Zero complaints! Enjoyed our stay and will stay again!"
A verified traveler stayed at Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Explore More Ways to Travel with Travelocity
- Hotels near Long Branch State Park
- Hotels near Union Covered Bridge States Historic Site
- Lodges in Hurdland
- Farmstay in Shelbyville
- Shelbyville Hotels
- Motels in Shelbyville
- Edina Hotels
- Lodges in Edina
- Hotels near Mark Twain Lake
- Hotels near Mark Twain Casino
- 5 Star Hotels in Monroe City
- Farmstay in Monroe City
- B&B in Monroe City
- Cabins in Monroe City
- Condos in Monroe City
- Monroe City Hotels
- Motels in Monroe City
- Vacation Homes in Monroe City
- Maywood Hotels
- Atlanta Hotels
- Hotels near Truman State University
- La Grange Hotels
- Rutledge Hotels
- Hotels near Stephen's Park
- Gibbs Hotels
- Hotels near Jackson Street Park
- Stoutsville Hotels
- Canton Hotels
- B&B in Shelbina
- Cabins in Shelbina
- Shelbina Hotels
- Motels in Shelbina
- Vacation Homes in Shelbina
- Hotels near Wakonda State Park
- Bevier Hotels
- Hotels near La Plata Golf Course
- Paris Hotels
- Palmyra Hotels
- Hotels near Kirksville Municipal
- 4 Star Hotels in Hunnewell
- Cabins in Hunnewell
- Motels in Hunnewell
- Taylor Hotels
- Hotels near Mark Twain State Park
- Historic Hotels in La Plata
- Hotels with a Gym in La Plata
- La Plata Hotels
- Hotels near Mark Twain Birthplace State Historic Site
- 3 Star Hotels in Macon
- Apartments in Macon
- Cabins in Macon
- Cottages in Macon
- Cheap Hotels in Macon
- Golf Resorts & in Macon
- Historic Hotels in Macon
- Hotels with Pools in Macon
- Hotels with Hot Tubs in Macon
- Hotels with an Indoor Pool in Macon
- Pet Friendly Hotels in Macon
- Macon Hotels
- Lodges in Macon
- Motels in Macon
- Vacation Homes in Macon
- Holliday Hotels
- Flights to Monroe City
- Flights to Shelbina
- Flights from Kirksville Municipal
- American Airlines Springfield (SPI) to Kirksville (IRK) flights
- American Airlines Albuquerque (ABQ) to Kirksville (IRK) flights
- American Airlines Dallas (DFW) to Kirksville (IRK) flights
- American Airlines Fort Lauderdale (FLL) to Kirksville (IRK) flights
- American Airlines Chicago (ORD) to Kirksville (IRK) flights
- Cape Air St. Louis (STL) to Kirksville (IRK) flights
- Cape Air Chicago (ORD) to Kirksville (IRK) flights
- Delta Atlanta (ATL) to Kirksville (IRK) flights
- United Indianapolis (IND) to Kirksville (IRK) flights
- Flights from Augusta (AGS) to Kirksville (IRK)
- Flights from Albany (ALB) to Kirksville (IRK)
- Flights from Burlington (BTV) to Kirksville (IRK)
- Flights from Columbia (COU) to Kirksville (IRK)
- Flights from Detroit (DTW) to Kirksville (IRK)
- Flights from Grand Rapids (GRR) to Kirksville (IRK)
- Flights from Jacksonville (JAX) to Kirksville (IRK)
- Flights from Kansas City (MCI) to Kirksville (IRK)
- Flights from Orlando (MCO) to Kirksville (IRK)
- Flights from Minneapolis (MSP) to Kirksville (IRK)
- Flights from Omaha (OMA) to Kirksville (IRK)
- Flights from Chicago (ORD) to Kirksville (IRK)
- Flights from Louisville (SDF) to Kirksville (IRK)
- Flights from St. Louis (STL) to Kirksville (IRK)
- Flights from Tri-Cities (TRI) to Kirksville (IRK)
- Flights to Macon
