Book Hotels in Northeast Missouri, MO

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Top Northeast Missouri hotels

Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

3 out of 5
201 S 20th St St. Louis MO
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $142 total per night from Jan 4 to Jan 5
$142 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
Merry Christmas

Reviewed on Dec 24, 2025

Opens in a new windowDrury Inn & Suites St. Louis Union Station
Live by Loews - St.Louis

Live by Loews - St.Louis

4 out of 5
799 Clark ave St. Louis MO
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $177 total per night from Dec 30 to Dec 31
$177 total
Dec 30 - Dec 31
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...
Clean room, great restaurant and bar down stairs

Reviewed on Dec 20, 2025

Opens in a new windowLive by Loews - St.Louis
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $172 total per night from Jan 5 to Jan 6
$172 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
The entire hotel was fantastic. Beautifully decorated, so much to see. The art gallery was fantastic, the servers at the bar were friendly and phenomenal and just made for a great evening. The food was fantastic. Every inch of the building was well styled and the room was fantastic. Can’t wait to ...

Reviewed on Dec 22, 2025

Opens in a new window21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $115 total per night from Dec 30 to Dec 31
$115 total
Dec 30 - Dec 31
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The staff were wonderful. The room was clean and the shower had amazing water pressure !!

Reviewed on Dec 24, 2025

Opens in a new windowClayton Plaza Hotel & Extended Stay
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $154 total per night from Jan 2 to Jan 3
$154 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...
Great property.

Reviewed on Dec 22, 2025

Opens in a new windowAngad Arts Hotel St. Louis, Tapestry Collection by Hilton
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $115 total per night from Jan 25 to Jan 26
$115 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
Great stay. Superb staff. Rooms were beautiful except bathroom very dated and the corners were not very clean

Reviewed on Dec 25, 2025

Opens in a new windowMagnolia Hotel St. Louis, a Tribute Portfolio Hotel
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Jan 16 to Jan 17
$143 total
Jan 16 - Jan 17, 2026
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Clean rooms and friendly, accommodating staff.

Reviewed on Dec 24, 2025

Opens in a new windowRenaissance St. Louis Airport Hotel
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $91 total per night from Jan 16 to Jan 17
$91 total
Jan 16 - Jan 17, 2026
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center ...
I like

Reviewed on Dec 26, 2025

Opens in a new windowHome2 Suites by Hilton St. Louis Downtown
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $98 total per night from Jan 4 to Jan 5
$98 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Room was pleasant. One bed had a broken leg so it was crooked which was a little uncomfortable. Shower would not fully turn on so the pressure was awful. Breakfast was awful - self making pancakes came out like rubber, the mini blueberry muffins tasted like chemicals. Eggs were dry & most of the ...

Reviewed on Dec 27, 2025

Opens in a new windowHeritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Northeast Missouri hotels

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Northeast Missouri hotel reviews by fellow wanderers

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