Book Hotels in Northeast Missouri, MO
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Top Northeast Missouri hotels

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Dec 23 to Dec 24
$106 total
Dec 23 - Dec 24
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Great place to stay before your early morning flight.
Reviewed on Dec 17, 2025

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Dec 25 to Dec 26
$162 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Hotel was very cool, certainly niche. Service was not the best. There was a language barrier between us and the receptionist. Definitely scour the area before arrival to find parking, otherwise you'll have to pay to park. the restaurants inside are really great, food and drinks are highly recommended. ...
Reviewed on Dec 13, 2025

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $105 total per night from Dec 21 to Dec 22
$105 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The bed was comfortable and the shower was fantastic (digital controls). There was a gap under the door to the hallway and there was light spilling in. The floors in our room were not cleaned - there were crumbs on them and some kind of food stuck in one place.
Reviewed on Dec 12, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$80 nightly
The price is $95 total per night from Dec 22 to Dec 23
$95 total
Dec 22 - Dec 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
Great service, clean place, tasty cookies
Reviewed on Dec 14, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton
1820 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $184 total per night from Dec 25 to Dec 26
$184 total
Dec 25 - Dec 26
Total with taxes and fees
This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...
Beautufully decorated room. Very clean. Easy check in. Food available on site.
Reviewed on Dec 14, 2025

Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Jan 2 to Jan 3
$138 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
Room was
Reviewed on Dec 13, 2025

Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $91 total per night from Dec 25 to Dec 26
$91 total
Dec 25 - Dec 26
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center ...
Great place, friendly staff!!
Reviewed on Dec 13, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $98 total per night from Dec 22 to Dec 23
$98 total
Dec 22 - Dec 23
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Good
Reviewed on Dec 13, 2025

Hilton St. Louis Airport
10330 Natural Bridge Rd St. Louis MO
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $137 total per night from Dec 26 to Dec 27
$137 total
Dec 26 - Dec 27
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the express check-in, express check-out, and free ...
I like the remodel of the lobby and lounge areas. The room was as expected. Check in was fairly easy at the desk and staff was polite.
Reviewed on Dec 18, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Northeast Missouri hotels

Quality Inn St. Louis Airport Hotel
10232 Natural Bridge Rd St. Louis MO
$53 nightly
The price is $62 total per night from Jan 11 to Jan 12
$62 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
6/10 (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Northeast Missouri with star-rating
Check Northeast Missouri Hotels by Star Rating

5 Star Hotels
1 properties
Recent Northeast Missouri hotel reviews by fellow wanderers

Pear Tree Inn St. Louis Airport
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Great place to stay before your early morning flight. "
A verified traveler stayed at Pear Tree Inn St. Louis Airport
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