Book Hotels in Northeast Missouri, MO
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Top Northeast Missouri hotels
Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Dec 18 to Dec 19
$106 total
Dec 18 - Dec 19
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
Friendly staff. Clean room. Room was absolutely huge! Breakfast options were great
Reviewed on Dec 11, 2025
21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Dec 21 to Dec 22
$162 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
The rooms were well curated, super crisp and really nicely designed.
Reviewed on Dec 8, 2025
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $106 total per night from Dec 21 to Dec 22
$106 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy ...
The bed was comfortable and the shower was fantastic (digital controls). There was a gap under the door to the hallway and there was light spilling in. The floors in our room were not cleaned - there were crumbs on them and some kind of food stuck in one place.
Reviewed on Dec 12, 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Fully refundableReserve now, pay when you stay
$87 nightly
The price is $104 total per night from Dec 17 to Dec 18
$104 total
Dec 17 - Dec 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...
Loved staying here, it was very clean and beautifully decorated.. friendly service and very close to my venue
Reviewed on Dec 8, 2025
Renaissance St. Louis Airport Hotel
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $138 total per night from Jan 2 to Jan 3
$138 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
The staff was amazing
Reviewed on Dec 7, 2025
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
$117 nightly
The price is $137 total per night from Jan 6 to Jan 7
$137 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
A casino, 7 restaurants, and a 24-hour gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, express check-out, ...
Room was clean and staff was helpful
Reviewed on Dec 8, 2025
Home2 Suites by Hilton St. Louis Downtown
1221 Locus Street St. Louis MO
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $89 total per night from Dec 20 to Dec 21
$89 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast and free WiFi. Traveling on business? Take advantage of the 24-hour business center ...
I wouldn't say spotless, but very clean. Privacy curtain in bathroom didnt close. Thermostat to 76 and still didn't warm very well. Comfortable bed.
Reviewed on Dec 9, 2025
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $98 total per night from Dec 15 to Dec 16
$98 total
Dec 15 - Dec 16
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
All was very good BUT there was a bug crawling on my partner's leg at one point. Not sure if he brought it in or if it was already in the room. Otherwise, everything else was clean and comfortable.
Reviewed on Dec 9, 2025
Hilton St. Louis Airport
10330 Natural Bridge Rd St. Louis MO
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $137 total per night from Dec 20 to Dec 21
$137 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the express check-in, express check-out, and free ...
Room was clean and staff quick and polite.
Reviewed on Dec 11, 2025
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See all available properties in Northeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Northeast Missouri hotels
Quality Inn St. Louis Airport Hotel
10232 Natural Bridge Rd St. Louis MO
$56 nightly
The price is $66 total per night from Jan 11 to Jan 12
$66 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
6/10 (1,002 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Northeast Missouri with star-rating
Check Northeast Missouri Hotels by Star Rating
5 Star Hotels
1 properties
Recent Northeast Missouri hotel reviews by fellow wanderers
Clayton Plaza Hotel & Extended Stay
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Friendly staff, amazing breakfast! "
A verified traveler stayed at Clayton Plaza Hotel & Extended Stay
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