Book Hotels in Palmyra, MO
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Top Palmyra hotels

Oak Hill Inn & Suites
Everything was absolutely perfect for our stay. Everything was incredibly clean, in great condition, and smelled nice! We didnt use the pool or hot tub because we had a jacuzzi in our room, but I did pop in and look. The pool and hot tub were just as clean as the rest of the hotel. Breakfast was ...
Reviewed on May 10, 2026

Heritage Hotel Quincy
Good price for a decent hotel. Stayed overnight for work. Place is much improved from previous owners. Not perfect, but for the price it is a good place to spend the night.
Reviewed on May 11, 2026

Holiday Inn Quincy East by IHG
Well, there was a cockroach in the bathroom of the hotel of my room, and I reported it to the front desk and he says that that’s very rare that that happens as if it happens and then offered to accommodate me and no kind of way totally disappointed
Reviewed on May 10, 2026

Stoney Creek Inn Quincy
Lovely and cozy stay. Very friendly staff.
Reviewed on May 11, 2026

Best Western On The River
Right downtown, restaurants in walking distance.. pool was cool, dated property.. parking available and safe place to stay. We would stay again
Reviewed on May 11, 2026

Quality Inn & Suites Hannibal West
Great hotel.. one of the nicer ones in Hannibal… hope you like cameras because they have a lot of them… friendly staff, safe place to stay.
Reviewed on May 11, 2026

Microtel Inn & Suites by Wyndham Quincy Downtown/River Area
All good
Reviewed on May 11, 2026

AmericInn by Wyndham Quincy
Beds were comfy. Very clean and staff is Amazing!
Reviewed on Apr 30, 2026

Motel 6 Hannibal, MO
Parking was easy and secure. Check in was flawless. The room was clean and comfy
Reviewed on May 11, 2026
Palmyra Hotel & Travel Guide\n
Visitors to Palmyra should consider securing somewhere to rest and relax well in advance of their departure date, as there isn't a vast selection of options near where the locals live in Palmyra.
The Budget Inn Palmyra is the nearest accommodation to central Palmyra and the sole one less than a quick drive away.
The Hannibal Garden House Bed and Breakfast is located 13 miles (20 kilometers) from the main part of Palmyra. Or, alternatively, the Holiday Inn Quincy East is located 15 miles (24 kilometers) away. The Fairfield Inn & Suites Quincy and also the Hampton Inn Quincy are some other hotel options around Palmyra.
When you have some spare time, adventurous travelers could venture to the other parts of St. Louis - Northeast Missouri. St. Louis - Northeast Missouri is home to prairies, and other commonly visited tourist sites are history museums. In this corner of United States of America visitors can take up the chance to partake in mountain biking, hiking and cycling.
The closest accommodations in Hannibal include Clarksville and Quincy, IL. Clarksville is 45 miles (74 kilometers) to the southeast of Palmyra, while Quincy, IL is 14 miles (22 kilometers) to the southeast. Travelocity-listed lodgings in Clarksville include the Rackheath House and Cedarcrest Manor. The Stoney Creek Quincy and Town & Country Inn and Suites are a selection of the Travelocity-registered room options in Quincy, IL.
Palmyra features some interesting scenic attractions; come across more by spending a few minutes at Travelocity's complete Palmyra travel guide.
Frequently asked questions
Recent Palmyra hotel reviews by fellow wanderers

Baymont by Wyndham Hannibal
Explore More Ways to Travel with Travelocity
- Hotels near Planters Barn Theater
- Hotels near Mark Twain Cave
- 3 Star Hotels in Hannibal
- 4 Star Hotels in Hannibal
- B&B in Hannibal
- Cabins in Hannibal
- Pod Hotels in Hannibal
- Guest Houses in Hannibal
- Casino Resorts & in Hannibal
- Cheap Hotels in Hannibal
- Convention Center Hotels in Hannibal
- Golf Resorts & in Hannibal
- Hilton Hotels in Hannibal
- Historic Hotels in Hannibal
- Hotels with Pools in Hannibal
- Hotels with a Lazy River in Hannibal
- Hotels with Balconies in Hannibal
- Hotels with Bar in Hannibal
- Hotels with Hot Tubs in Hannibal
- Hotels with an Indoor Pool in Hannibal
- Hotels with smoking rooms in Hannibal
- Luxury Hotels in Hannibal
- Marriott Hotels & Resorts in Hannibal
- Pet Friendly Hotels in Hannibal
- Romantic Getaways & Hotels in Hannibal
- Spa Resorts & in Hannibal
- Winery Hotels in Hannibal
- Hannibal Hotels
- Motels in Hannibal
- Vacation Homes in Hannibal
- Resorts in Hannibal
- Safari Camps in Hannibal
- Hotels near Mark Twain State Park
- Hotels near Big River Train Town
- Hotels near Molly Brown Museum and Home
- 5 Star Hotels in Monroe City
- Farmstay in Monroe City
- B&B in Monroe City
- Cabins in Monroe City
- Condos in Monroe City
- Monroe City Hotels
- Motels in Monroe City
- Vacation Homes in Monroe City
- Hotels near Wakonda State Park
- Maywood Hotels
- Cabins in Saverton
- Hotels near Mark Twain Boyhood Home and Museum
- Perry Hotels
- Hotels near Mark Twain Memorial Lighthouse
- Hotels near Bluff City Theater
- B&B in La Grange
- Cabins in La Grange
- Guest Houses in La Grange
- La Grange Hotels
- Motels in La Grange
- Stoutsville Hotels
- Cabins in New London
- New London Hotels
- Motels in New London
- Shelbina Hotels
- Hotels near Mark Twain Casino
- Hotels near Rockcliffe Mansion
- Hotels near Sawyer's Creek Fun Park
- Paris Hotels
- Shelbyville Hotels
- Hotels near Mark Twain Birthplace State Historic Site
- 4 Star Hotels in Hunnewell
- Cabins in Hunnewell
- Motels in Hunnewell
- B&B in Taylor
- Guest Houses in Taylor
- Taylor Hotels
- Motels in Taylor
- Vacation Homes in Taylor
- Hotels near Mark Twain Cave and Cameron Cave
- Hotels near Mark Twain Lake
- Northeast Missouri Hotels
- Vandalia Hotels
- Cabins in Canton
- Guest Houses in Canton
- Casino Resorts & in Canton
- Spa Resorts & in Canton
- Canton Hotels
- Frankford Hotels






