Explore top 2025 4 Star Hotels in Northeast Missouri

Name: DoubleTree by Hilton St. Louis Forest Park
Price range: $144 total
Rating: 8.2

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Top Northeast Missouri 4 Star hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

421 N 8th St, St. Louis, MO

Fully refundableReserve now, pay when you stay

$85 nightly

$101 total

Oct 26 - Oct 27

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.6/10 Excellent! (1,049 reviews)

"The valet is why I gave a 4/5"

Reviewed on Oct 20, 2025

St. Louis Union Station Hotel, Curio Collection by Hilton

1820 Market Street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$166 nightly

$198 total

Nov 2 - Nov 3

Total with taxes and fees

This historic hotel's 7 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Enjoy the seasonal outdoor pool and perks like free ...

8.4/10 Very Good! (1,016 reviews)

Amazing-Kind- Luxurious

"Everyone was incredible, all staff was really friendly. We stayed for the Adam Sandler concert and it was a short walk over to the Enterprise Center. We also were comped a really nice breakfast because of a slight issue with our keys that was easily fixed. Amazing time!"

Reviewed on Oct 18, 2025

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

3550 Samuel Sheppard Drive, St. Louis, MO

Fully refundableReserve now, pay when you stay

$127 nightly

$150 total

Oct 28 - Oct 29

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, along with free WiFi in public areas. ...

8.6/10 Excellent! (1,015 reviews)

"Charming hotel full of amazing works of art. The roof top bar is a great place for drinks and views of the city."

Reviewed on Oct 15, 2025

The Cheshire

6300 Clayton Rd, Richmond Heights, MO

Fully refundableReserve now, pay when you stay

$129 nightly

$153 total

Oct 26 - Oct 27

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

8.4/10 Very Good! (1,015 reviews)

"The hotel staff was very accommodating and the restaurants and pub on aite are amazing. Note for parents the windows in the rooms do open amd we had a small scare with iur toddler, but Diane was very accommodating and made sure we gat a room that was better for our family (no furniture within reach ..."

Reviewed on Oct 19, 2025

21C Museum Hotel St Louis

1528 Locust street, St. Louis, MO

Fully refundableReserve now, pay when you stay

$143 nightly

$167 total

Oct 31 - Nov 1

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,416 reviews)

"Some things missing from room and we called the front desk but they never showed up. The air conditioner was very loud and kept us up. The pool area was great but out of towels."

Reviewed on Oct 19, 2025

DoubleTree by Hilton St. Louis Airport

4505 Woodson Road, St. Louis, MO

Fully refundableReserve now, pay when you stay

$110 nightly

$129 total

Oct 26 - Oct 27

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Bring the family and enjoy the arcade/game room and kid-friendly dining. There's no skimping ...

7.8/10 Good! (831 reviews)

"Nice room floor in entry way of the could be cleaner"

Reviewed on Oct 14, 2025

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road, St. Louis, MO

Fully refundableReserve now, pay when you stay

$118 nightly

$138 total

Oct 31 - Nov 1

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...

8.4/10 Very Good! (1,027 reviews)

"I was very confused with parking at the beginning. Afraid i wouldn't be able to park or get in without paying fee's."

Reviewed on Oct 16, 2025

Marriott St. Louis Grand

800 Washington Ave, St. Louis, MO

Fully refundableReserve now, pay when you stay

$127 nightly

$151 total

Nov 2 - Nov 3

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8/10 Very Good! (1,011 reviews)

"On"

Reviewed on Oct 13, 2025

Live by Loews - St.Louis

799 Clark ave, St. Louis, MO

Fully refundableReserve now, pay when you stay

$149 nightly

$177 total

Nov 21 - Nov 22

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

9.2/10 Wonderful! (1,058 reviews)

"Clean and good"

Reviewed on Oct 18, 2025

DoubleTree by Hilton St. Louis Forest Park

4550 Forest Park Ave, St. Louis, MO

Fully refundableReserve now, pay when you stay

$122 nightly

$144 total

Nov 2 - Nov 3

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Self parking, ...

8.2/10 Very Good! (1,004 reviews)

"Clean and convenient to hospital."

Reviewed on Oct 18, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Northeast Missouri

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Northeast Missouri 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Northeast Missouri will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Northeast Missouri, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.