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Top Kirksville hotels

Holiday Inn Express & Suites Kirksville - University Area by IHG
Reviewed on Sep 28, 2025

Hampton Inn Kirksville
Reviewed on Sep 21, 2025

Thousand Hills
Reviewed on Sep 27, 2025

Super 8 by Wyndham Kirksville-University Area
Reviewed on Sep 28, 2025

Baymont by Wyndham Kirksville University Area
Reviewed on Sep 22, 2025

Quality Inn Kirksville
Reviewed on Sep 28, 2025

Knights Inn Kirksville
Reviewed on May 18, 2025

Days Inn by Wyndham Kirksville
Reviewed on Aug 15, 2025

New tiny home in an incredible private setting among all nature has to offer.
Reviewed on Sep 15, 2025
Cheap Kirksville hotels

Budget Host Village Inn
Kirksville Hotel & Travel Guide\n
St. Louis, Missouri, was often an important stop for travelers headed west in the 19th century. Far from home and on the cusp of a vast and unknown territory, these visitors would have looked around them at the untamed, verdant land before them and been awestruck.
It’s a feeling you can experience for yourself, without the looming threat of a broken axle on your covered wagon, in Kirksville MO. Hotels in the area are thankfully more modern, with heated pools, room service, and fresh towels to welcome you home after a hike in through the dazzling landscape.
Visiting Kirksville
In essence, this quaint township has maintained its rugged, “edge of civilization” appeal with a few concessions to the 21st century, like Kirksville rental cars in place of horse-drawn wagons.
It’s also possible to fish the Mississippi and Missouri Rivers for your evening’s dinner, roast it over a crackling orange fire, and enjoy a night sleeping on the grass beneath thick, moonlit branches.
But fear not, connected traveler: You can also get Wi-Fi and phone service, so you’ll be able to navigate your way back to hotels in Kirksville MO when you long for a fresh continental breakfast buffet the following day. This land – which spent so long at the edge of the frontier – is also prime soil for vineyards. With every indulgent sip, you’ll also get a taste of local history as resident historians help you explore Native American petroglyphs nearby.
Whether you’re searching for an urban or rural adventure, Travelocity, has vacation packages that make following your inspiration easy. Hotels near Kirksville put you closer to the hills and lakes where you long to get lost for a while, and hotels in St. Louis are there for when you want to be found again. Book your trip now and head off to see more wild, yet convenient, corners of the world.
Frequently asked questions
Recent Kirksville hotel reviews by fellow wanderers

Holiday Inn Express & Suites Kirksville - University Area by IHG
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