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Top hotels in Isle of Palms

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH Jacksonville FL
Fully refundableReserve now, pay when you stay
$175 nightly
The price is $199 total per night from Mar 20 to Mar 21
$199 total
Mar 20 - Mar 21
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
Great stay! Clean room, friendly staff.

Reviewed on Mar 3, 2026

Opens in a new windowResidence Inn By Marriott Jacksonville - Mayo Clinic Area
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
1515 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$180 nightly
The price is $204 total per night from Apr 5 to Apr 6
$204 total
Apr 5 - Apr 6
Total with taxes and fees
This hotel features 2 outdoor pools, a 24-hour gym, and a restaurant. Unwind with a drink at one of the 2 bars/lounges and enjoy free perks like full breakfast ...
Location was great and I loved the property. It had a pool, hot tub, free breakfast, a musician in the bar at night on the weekends and a cool tiki bar in the back. Lots of parking both near the entrance and across the street. Staff was friendly and the food was good.

Reviewed on Mar 3, 2026

Opens in a new windowHampton Inn Jacksonville Beach/Oceanfront
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $203 total per night from Mar 8 to Mar 9
$203 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Beautiful beach view from the balcony. Great valet parking. Landshark Bar and Grille onsite! Perfect location for walking the beach or pier. Had a great time!!

Reviewed on Mar 5, 2026

Opens in a new windowMargaritaville Jacksonville Beach
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $175 total per night from Apr 4 to Apr 5
$175 total
Apr 4 - Apr 5
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
Check out staff member was a bit rude. She rolled her eyes at me at one point. The rooms were just ok. The view was very nice of the river.

Reviewed on Mar 5, 2026

Opens in a new windowHyatt Regency Jacksonville
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

3 out of 5
14565 Duval Rd Jacksonville FL
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Mar 9 to Mar 10
$129 total
Mar 9 - Mar 10
Total with taxes and fees
This hotel features an outdoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Great place. Great service. Room is pretty big and nicely laid out.

Reviewed on Mar 5, 2026

Opens in a new windowHyatt Place Jacksonville Airport
Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG

2.5 out of 5
10148 New Berlin Rd Jacksonville FL
Fully refundable
$89 nightly
The price is $101 total per night from Mar 23 to Mar 24
$101 total
Mar 23 - Mar 24
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
I really enjoyed my stay. The room was perfect. The hostess at the front desk was really sweet nice and polite. I would recommend this to my friends and family.

Reviewed on Mar 5, 2026

Opens in a new windowHoliday Inn Express Jacksonville - Blount Island by IHG
Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport

2.5 out of 5
15678 Max Leggett Parkway Jacksonville FL
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $113 total per night from Mar 22 to Mar 23
$113 total
Mar 22 - Mar 23
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like on-the-go breakfast and WiFi in public ...
Stayed for one night February 28th 2026. The room was very big, clean as a whistle, very quiet. The desk staff were all very kind and helpful.

Reviewed on Mar 4, 2026

Opens in a new windowExtended Stay America Premier Suites - Jacksonville - Airport
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
8 Amelia Village Circle, Amelia Island Fernandina Beach FL
This smoke-free vacation home features a golf course, a full-service spa, and 9 restaurants. Enjoy a day at the beach kayaking, or relax with beach cabanas. ...
Loved this resort and amenities!

Reviewed on Mar 2, 2026

Opens in a new windowThe Villas of Amelia Island
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road Jacksonville FL
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Mar 8 to Mar 9
$96 total
Mar 8 - Mar 9
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The rooms need updating. Bed sheets had stains on them, very gross. Hotel company needs to fumigate rooms, saw several roaches in the room.

Reviewed on Mar 5, 2026

Opens in a new windowWyndham Garden Jacksonville
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isle of Palms Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Isle of Palms area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Isle of Palms to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Isle of Palms are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

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