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Top hotels in Isle of Palms

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $188 total per night from Nov 8 to Nov 9
$188 total
Nov 8 - Nov 9
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
"The lights seem to be out in the parking lot. It was extremely dark in the morning and hard to see to get to car. Seems unsafe. Lights need to be turned on. Otherwise, excellent stay"

Reviewed on Oct 13, 2025

Opens in a new windowResidence Inn By Marriott Jacksonville - Mayo Clinic Area
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr, Jacksonville, FL
$158 nightly
The price is $179 total per night from Nov 21 to Nov 22
$179 total
Nov 21 - Nov 22
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
"Clean room and beautiful views."

Reviewed on Oct 20, 2025

Opens in a new windowHyatt Regency Jacksonville
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N, Jacksonville Beach, FL
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $197 total per night from Oct 27 to Oct 28
$197 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Was a nice place to stay. Wasn’t our brand of motel but we made out and had a good trip."

Reviewed on Oct 17, 2025

Opens in a new windowMargaritaville Jacksonville Beach
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

3 out of 5
14565 Duval Rd, Jacksonville, FL
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $106 total per night from Nov 2 to Nov 3
$106 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
"Nicely appointed and maintained"

Reviewed on Oct 19, 2025

Opens in a new windowHyatt Place Jacksonville Airport
Omni Amelia Island Resort & Spa

Omni Amelia Island Resort & Spa

4 out of 5
39 Beach Lagoon Road, Fernandina Beach, FL
Fully refundableReserve now, pay when you stay
$303 nightly
The price is $340 total per night from Nov 16 to Nov 17
$340 total
Nov 16 - Nov 17
Total with taxes and fees
This smoke-free resort features a golf course, a full-service spa, and 9 restaurants. Enjoy a day at the beach surfing, or relax with beach cabanas. There's ...
"Beautiful property with exceptional staff. Deidra at the front desk was very friendly and professional. Made us feel at home."

Reviewed on Oct 18, 2025

Opens in a new windowOmni Amelia Island Resort & Spa
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
9300 Baymeadows Road, Jacksonville, FL
$114 nightly
The price is $129 total per night from Oct 27 to Oct 28
$129 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the express check-in and WiFi in public areas. Enjoy ...
"The room was clean. Area was quiet. Staff was friendly"

Reviewed on Oct 18, 2025

Opens in a new windowEmbassy Suites by Hilton Jacksonville Baymeadows
Crowne Plaza Hotel Jacksonville Airport/I-95N by IHG

Crowne Plaza Hotel Jacksonville Airport/I-95N by IHG

3.5 out of 5
14670 Duval Road, Jacksonville, FL
$84 nightly
The price is $95 total per night from Oct 28 to Oct 29
$95 total
Oct 28 - Oct 29
Total with taxes and fees
This hotel features 2 restaurants and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"Bathrooms are in poor shape. If you look in the corners you see the problem"

Reviewed on Oct 17, 2025

Opens in a new windowCrowne Plaza Hotel Jacksonville Airport/I-95N by IHG
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road, I-95 Exit 344 (Butler Boulevard), Jacksonville, FL
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Nov 9 to Nov 10
$79 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"Good location to where we were going. Clean ,quiet room"

Reviewed on Oct 19, 2025

Opens in a new windowWyndham Garden Jacksonville
DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront

4 out of 5
1201 Riverplace Boulevard, Jacksonville, FL
$114 nightly
The price is $129 total per night from Nov 2 to Nov 3
$129 total
Nov 2 - Nov 3
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi. ...
"Mold in the shower, bottle caps found on floor near balcony door, shower doors not cleaned most importantly they was no refrigerator for our drinks ( water, pop ) had to go to get ice 3-4 times a day just to keep our drinks cold Staff was amazing especially Alvita when checking in her Attitude, friendliness, ..."

Reviewed on Oct 18, 2025

Opens in a new windowDoubleTree by Hilton Hotel Jacksonville Riverfront
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isle of Palms Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Isle of Palms area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Isle of Palms to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Isle of Palms are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

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