Find a Hotel in Downtown South San Francisco
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Top hotels in Downtown South San Francisco

Hyatt Regency San Francisco
Given the price I paid for my stay at the hotel, I don't think the value matches the cost. There are hotels with lower prices, but these are much more comfortable and convenient. We chose a hotel package that included breakfast, but there was no breakfast available. The only option was a buffet at ...
Reviewed on May 6, 2026

Hotel Riu Plaza Fisherman's Wharf
Breakfast beats most hotels providing free breakfasts. The staff was exceptionally helpful and cheerful. The room is decent size and clean.
Reviewed on May 6, 2026

Holiday Inn Golden Gateway by IHG
Great staff, helpful, quick check in / out. Great location.
Reviewed on May 5, 2026

Club Quarters Hotel in San Francisco
The entire staff was phenomenal. They all went above and beyond to make sure my experience was the best possible. I’ve never stayed at a Club Quarters. Now, I will become a regular!
Reviewed on May 5, 2026

Handlery Union Square Hotel
Clean room, neighborhood ok
Reviewed on May 6, 2026

Hilton San Francisco Financial District
The price was under a $150 but then we paid $65 for parking. The lobby itself is very clean, the room had a weird smell to it. Definitely not a fan of the location. The surrounding areas were very dirty and a lot of homeless people.
Reviewed on May 5, 2026

Parc 55 San Francisco - A Hilton Hotel
Located in one of the most walkable area of San Francisco. Everything is within walking distance.
Reviewed on May 5, 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Would have been a better experience if parking was free
Reviewed on May 6, 2026

YOTEL San Francisco
This hotel was not good. Tiny, dusty room. It was not completely finished which caused it to be dusty. This dust was not well cleaned either. Pictures included. The room was quite small with the toilet being out in the open. Shower was small but decent with a rainfall shower. The lights were very ...
Reviewed on May 6, 2026
Downtown South San Francisco Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Downtown South San Francisco area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Downtown South San Francisco to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Downtown South San Francisco are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Downtown South San Francisco hotel reviews by fellow wanderers

Hilton San Francisco Union Square
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