Find a Hotel in Mission District
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Top hotels in Mission District

Hyatt Regency San Francisco
"Staff was very friendly and helpful! The buffet breakfast was very expensive and not very good"
Reviewed on Jun 28, 2026

Hotel Zoe Fisherman's Wharf
"Maybe provide water upon arrival?"
Reviewed on Jun 27, 2026

Holiday Inn Golden Gateway by IHG
"We have stayed here before and had a great experience. This time our first room had a smoke smell to it so I went back to the front desk and they immediately switched our room, no questions asked. I was very appreciative since we didn’t want our clothes to smell as we went out. The rooms are great! ..."
Reviewed on Jun 27, 2026

Club Quarters Hotel in San Francisco
"Amazing Hotel really close to the embarcadero. This hotel is located in the financial district between the places to visit. Staff was great like always and there's lots of parking nearby. Room was clean and air conditioning was amazing."
Reviewed on Jun 26, 2026

Hotel Riu Plaza Fisherman's Wharf
"Very clean"
Reviewed on Jun 27, 2026

Hilton San Francisco Financial District
"Loved my stay at the Hilton, excellent location. The staff is great, we got a room with a nice view of the bay and Coit tower. I definitely recommend this hotel if you want to be centrally located, I love walking so walking to the Embarcadero, Lombard Street and Coit tower was not a problem."
Reviewed on Jun 27, 2026

Handlery Union Square Hotel
"Good location but hotel is dated! Relatively clean throughout!"
Reviewed on Jun 27, 2026

Parc 55 San Francisco - A Hilton Hotel
"I would never go back. It was horrible. Disgusting everything in the room was disgusting and dirty. That whole hotel needs to be sanitize. Smells like piss everywhere. It’s horrible horrible horrible experience. It was my first time in San Francisco. Specially at the Hilton in San Francisco and it’s ..."
Reviewed on Jun 24, 2026

Hilton San Francisco Union Square
"Great Staff. Amazing views, especially from the bar"
Reviewed on Jun 26, 2026
Mission District Hotel Guide
Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.
Nowhere else can you find better deals on Mission District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Mission District to find the perfect one to will fit your budget.
Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Mission District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.
Recent Mission District hotel reviews by fellow wanderers

Hyatt Regency San Francisco
"Staff was very friendly and helpful! The buffet breakfast was very expensive and not very good"
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