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Top hotels in Mission District

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St San Francisco CA
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $189 total per night from Oct 4 to Oct 5
$189 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features a bar/lounge, free WiFi in public areas, and a computer station. Business travelers can take advantage of the laundry service. There's luggage ...
"Incredible hotel in an amazing location right on union square. Hotel was clean the bed was the comfiest I’ve slept in. Staff were wonderful and the little birthday gift on arrival was a lovely touch. Would defo rebook this hotel without a question."

Reviewed on Sep 23, 2026

Opens in a new windowChancellor Hotel on Union Square
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
$152 nightly
The price is $179 total per night from Oct 25 to Oct 26
$179 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's ...
"This in my fourth time at this location and it will be the only one if I come back. Clean, comfortable and safe! I fell totally secure. In a large city that is a must. Staff is always helpful and kind."

Reviewed on Sep 24, 2026

Opens in a new windowHoliday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $192 total per night from Oct 18 to Oct 19
$192 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"The breakfast was awesome and the rooms are clean. This is a great location. The staff were very friendly. The room was noisy due to the HVAC system. I’m not a light sleeper so it didn’t bother me but it was very loud. It’s recommended but wanted to mention the HVAC issue."

Reviewed on Sep 23, 2026

Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $168 total per night from Oct 22 to Oct 23
$168 total
Oct 22 - Oct 23
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. ...
"It was very comfortable and a great location"

Reviewed on Sep 24, 2026

Opens in a new windowHandlery Union Square Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $173 total per night from Oct 25 to Oct 26
$173 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and WiFi in public areas. Self ...
"The friendly and accommodating staff and the central location made the stay a truly memorable one. The hotel is only steps away from Chinatown, and it's the perfect place from which to begin exploring the city. The rooms were immaculate, and the staff were gracious to a fault. I would definitely ..."

Reviewed on Sep 23, 2026

Opens in a new windowHilton San Francisco Financial District
Grand Hyatt San Francisco

Grand Hyatt San Francisco

4 out of 5
345 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
$191 nightly
The price is $225 total per night from Oct 23 to Oct 24
$225 total
Oct 23 - Oct 24
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowGrand Hyatt San Francisco
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4 out of 5
200 Marina Blvd Berkeley CA
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Oct 22 to Oct 23
$149 total
Oct 22 - Oct 23
Total with taxes and fees
A marina, a gym, and a restaurant are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Opens in a new windowDoubleTree by Hilton Hotel Berkeley Marina
Club Quarters Hotel Embarcadero, San Francisco

Club Quarters Hotel Embarcadero, San Francisco

4 out of 5
424 Clay St San Francisco CA
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $142 total per night from Oct 18 to Oct 19
$142 total
Oct 18 - Oct 19
Total with taxes and fees
A restaurant and a 24-hour gym are featured at this hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. A coffee ...
Opens in a new windowClub Quarters Hotel Embarcadero, San Francisco
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
$163 nightly
The price is $192 total per night from Oct 23 to Oct 24
$192 total
Oct 23 - Oct 24
Total with taxes and fees
The hotel's outdoor pool, 24-hour gym, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center and ...
Opens in a new windowHilton San Francisco Union Square
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mission District Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Mission District area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Mission District to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Mission District are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Mission District hotel reviews by fellow wanderers

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"This in my fourth time at this location and it will be the only one if I come back. Clean, comfortable and safe! I fell totally secure. In a large city that is a must. Staff is always helpful and kind."
A verified traveler stayed at Holiday Inn Golden Gateway by IHG
Holiday Inn Golden Gateway by IHG

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