Explore top 2026 5 Star Hotels in Downtown St. Louis

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Mar 8 - Mar 9
Tomorrow
Mar 9 - Mar 10
Next weekend
Mar 13 - Mar 15
In two weeks
Mar 20 - Mar 22

Top Downtown St. Louis 5 Star hotels

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5 out of 5
999 North Second Street St. Louis MO
Fully refundableReserve now, pay when you stay
$325 nightly
The price is $380 total per night from Mar 12 to Mar 13
$380 total
Mar 12 - Mar 13
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...
9.4/10 Exceptional! (1,001 reviews)
Beautiful accommodations. Attentive and genuine staff. We felt like celebrities. Beyond first class service!!

Reviewed on Feb 23, 2026

Opens in a new windowFour Seasons Hotel St Louis
Don't see what you're looking for?
See all available properties in Downtown St. Louis
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Downtown St. Louis hotel reviews by fellow wanderers

The Westin St. Louis

The Westin St. Louis

2 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Room was gross, not super clean. Staff was helpful, but wouldn’t say again."
A verified traveler stayed at The Westin St. Louis
The Westin St. Louis

Explore More Ways to Travel with Travelocity