Explore top 2025 5 Star Hotels in Downtown St. Louis
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Top Downtown St. Louis 5 Star hotels

Four Seasons Hotel St Louis
999 North Second Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
$425 nightly
The price is $497 total per night from Oct 31 to Nov 1
$497 total
Oct 31 - Nov 1
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this luxury hotel. Families will appreciate kid-friendly dining and in-room childcare. ...
9.4/10 Exceptional! (1,000 reviews)
The views from the pool were great as well as the access to the Spa with the whirlpool. Restaurant experience was underwhelming for a very nice hotel but it was kind of convenient although service was NOT fast or attentive. The room did have a comfortable bed. First room had a bath tub that was not ...
Reviewed on Oct 5, 2025
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View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Downtown St. Louis hotel reviews by fellow wanderers

Hilton Pennywell St. Louis at the Arch
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Huge room in a neat hotel that feels like it is truly from another era. Highly recommend."
A verified traveler from Bradenton stayed at Hilton Pennywell St. Louis at the Arch
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