Explore top 2026 4 Star Hotels in Panama City

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Top Panama City 4 Star hotels

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$135 nightly
The price is $149 total per night from Apr 20 to Apr 21
$149 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
8.6/10 Excellent! (2,479 reviews)
Lovely food at their restaurant, clean rooms and perfect location close to airport

Reviewed on Mar 19, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Apr 3 to Apr 4
$148 total
Apr 3 - Apr 4
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
Opens in a new windowSheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Apr 20 to Apr 21
$109 total
Apr 20 - Apr 21
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
7.8/10 Good! (1,001 reviews)
For an older hotel, they keep it up.

Reviewed on Mar 18, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Mar 27 to Mar 28
$121 total
Mar 27 - Mar 28
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
8.8/10 Excellent! (791 reviews)
Not what the pictures show. Found a roach in my room. Bathroom dirty. Elevator dirty. Definitely does not match the reviews. Pool area is beautiful.

Reviewed on Mar 18, 2026

Opens in a new windowWaymore Hotel Spa & Casino
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $108 total per night from Mar 30 to Mar 31
$108 total
Mar 30 - Mar 31
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9.6/10 Exceptional! (1,149 reviews)
Great Hotel in downtown Panama City. The room waa clean and well cared for. The bathroom was spotless. Folks that work at the hotel super friendly and just a joy to deal with. My new go to for when I come to Panama

Reviewed on Mar 20, 2026

Opens in a new windowRamada Plaza by Wyndham Panama Punta Pacifica
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
$101 nightly
The price is $111 total per night from Apr 18 to Apr 19
$111 total
Apr 18 - Apr 19
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,002 reviews)
The room was fine, cleaning staff great. The front desk is a gong show. No one seemed to know what was going on, the staff were not helpful. The pool only had 4 lounge chairs, the cushions were very dirty. The pool was not clean and the pool decking was very dirty. Nothing had been scrubbed up there ...

Reviewed on Mar 19, 2026

Opens in a new windowCourtyard by Marriott Panama Multiplaza Mall
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $177 total per night from Apr 10 to Apr 11
$177 total
Apr 10 - Apr 11
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
9/10 Wonderful! (1,001 reviews)
Had a great time. This hotel is great

Reviewed on Mar 20, 2026

Opens in a new windowMarriott Panama Hotel
Novotel Panama City

Novotel Panama City

4 out of 5
Calle Jose I. Fabrega y Thais de Pons Panama City Panama
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $92 total per night from Apr 20 to Apr 21
$92 total
Apr 20 - Apr 21
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. There's fun for all ages with a free kid's club and a playground, and families will appreciate ...
9.2/10 Wonderful! (1,143 reviews)
Our stay at Novotel was uneventful but nice. The room was clean and attractive. There was a great variety of foods for breakfast. The staff was very cordial. We would definitely stay there again.

Reviewed on Mar 19, 2026

Opens in a new windowNovotel Panama City
Hyatt Regency Panama City

Hyatt Regency Panama City

4.5 out of 5
Calle 52 and Ricardo Arias Panama City
Fully refundableReserve now, pay when you stay
$143 nightly
The price is $157 total per night from Mar 24 to Mar 25
$157 total
Mar 24 - Mar 25
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public ...
9.8/10 Exceptional! (224 reviews)
We had a great stay at the Hyatt Regency Panama City! The hotel is beautiful, clean, and very well maintained. The staff was friendly and attentive, making the experience even better. The location is convenient and made it easy to get around and enjoy the area. Overall, a wonderful place to stay—we ...

Reviewed on Mar 19, 2026

Opens in a new windowHyatt Regency Panama City
American Trade Hotel

American Trade Hotel

4.5 out of 5
Plaza Herrera Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$234 nightly
The price is $258 total per night from Apr 14 to Apr 15
$258 total
Apr 14 - Apr 15
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...
9.4/10 Exceptional! (679 reviews)
I did a lot of research on where to stay. This hotel did not disappoint. From the moment I booked the hotel reached out and offered arrangements from the airport. Everything from airport pickup to dinner reservations was seamless. The hotel was even more beautiful in person. I would stay here ...

Reviewed on Mar 19, 2026

Opens in a new windowAmerican Trade Hotel
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4 Star Hotels Panama City

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Panama City 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Panama City will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Panama City, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Panama City hotel reviews by fellow wanderers

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