Explore top 2026 4 Star Hotels in Panama City
Seize Your Someday with our amazing deals for the whole family!
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top Panama City 4 Star hotels

Crowne Plaza Panama Airport by IHG
Poor at 6am
Reviewed on Apr 4, 2026

Sheraton Grand Panama
The breakfast menu was excellent. It covers ever taste.
Reviewed on Apr 2, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Was excellent all the staff
Reviewed on Apr 4, 2026

Waymore Hotel Spa & Casino
We chose to stay at the Waymore for our honeymoon to Panama. The best thing about this hotel is the location. There were a lot of food options and souvenir shops within walking distance of the hotel. I was sad to find out that the pool was closed for remodeling-they did not inform us of this prior ...
Reviewed on Apr 3, 2026

Ramada Plaza by Wyndham Panama Punta Pacifica
Reception desk was very accommodating and helped me check in earlier than 3:00 pm as I was visibly exhausted by the commute from the airport to the hotel. Breakfast was good, byt the yogurt…. (to die for with REAL FRESH strawberries )
Reviewed on Apr 5, 2026

Courtyard by Marriott Panama Multiplaza Mall
Very clean room, excellent staff, breakfast wonderful and amazing shopping.
Reviewed on Apr 4, 2026

Novotel Panama City
Yes
Reviewed on Apr 3, 2026

Marriott Panama Hotel
The main positive is the location with access to the mall.
Reviewed on Apr 3, 2026

American Trade Hotel
Staff was very helpful. Wish we had planned to stay longer.
Reviewed on Apr 4, 2026

Decapolis Hotel Panama City
Good breakfast options. Loved the pool lounge area. The bartender did an excellent job preparing our drinks.
Reviewed on Apr 1, 2026
4 Star Hotels Panama City
Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?
Come on, you deserve it!
The best part about staying in Panama City 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.
Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.
The best four star hotels in Panama City will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!
If you’re looking for 4 star hotels in Panama City, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.
Recent Panama City hotel reviews by fellow wanderers

Ramada Plaza by Wyndham Panama Punta Pacifica
More ways to wander Panama City
Explore More Ways to Travel with Travelocity
- Hotels near Albrook Shopping Mall
- Hotels near Hospital Punta Pacífica
- Hotels near Multiplaza Pacific Mall
- Boutique Hotels in Marbella
- Casino Resorts & in Marbella
- Cheap Hotels in Marbella
- Hotels with Suites in Marbella
- Luxury Hotels in Marbella
- Curundu Hotels
- Hotels near Avenida Balboa
- Adults Only Resorts & in Campo Alegre
- Campo Alegre Hotels
- Cheap Hotels in Santa Ana
- Luxury Hotels in Santa Ana
- Santa Ana Hotels
- All Inclusive Resorts & in Casco Viejo
- Beach Resorts & in Casco Viejo
- Boutique Hotels in Casco Viejo
- Casino Resorts & in Casco Viejo
- Cheap Hotels in Casco Viejo
- Convention Center Hotels in Casco Viejo
- Kid Friendly Hotels in Casco Viejo
- Golf Resorts & in Casco Viejo
- Hotels with Airport Transfers in Casco Viejo
- Hotels with Pools in Casco Viejo
- Hotels with Free Breakfast in Casco Viejo
- Hotels with Restaurants in Casco Viejo
- Hotels with smoking rooms in Casco Viejo
- Luxury Hotels in Casco Viejo
- Pet Friendly Hotels in Casco Viejo
- Spa Resorts & in Casco Viejo
- Hotel Wedding Venues Hotels in Casco Viejo
- Casco Viejo Hotels
- Barrio Chino Hotels
- Adventure Hotels in Bethania
- Bethania Hotels
- Hotels near Bingo 90
- Hotels near El Dorado Mall
- Hostels in Vía Argentina
- Hotels near Club de Clases y Tropas
- Hotels near Omar Torrijos Recreational Park
- Hotels near Pacific Center
- Historic Hotels in Calidonia
- Calidonia Hotels
- Hotels near ATLAPA Conventions Center
- Adults Only Resorts & in Panamá Province
- All Inclusive Resorts & in Panamá Province
- Gay Friendly Hotels in Panamá Province
- Green Hotels in Panamá Province
- Hotels with a Lazy River in Panamá Province
- Hotels with Free Parking in Panamá Province
- Hotels with Kitchenettes in Panamá Province
- Ski Resorts and in Panamá Province
- Panamá Province Hotels
- Hostels in Panamá Province
- Lodges in Panamá Province
- Hotels near Multicentro Panama
- Adults Only Resorts & in Punta Pacifica
- Beach Resorts & in Punta Pacifica
- Pet Friendly Hotels in Punta Pacifica
- Punta Pacifica Hotels
- Adults Only Resorts & in Bella Vista
- Luxury Hotels in Bella Vista
- Bella Vista Hotels
- Beach Resorts & in El Cangrejo
- Boutique Hotels in El Cangrejo
- Kid Friendly Hotels in El Cangrejo
- Gay Friendly Hotels in El Cangrejo
- Pet Friendly Hotels in El Cangrejo
- El Cangrejo Hotels
- Gay Friendly Hotels in Punta Paitilla
- Hotels with Free Airport Shuttle in Punta Paitilla
- Punta Paitilla Hotels
- Hotels near Cinta Costera
- Hotels near Uruguay Street
- Adults Only Resorts & in San Francisco
- Boutique Hotels in San Francisco
- Green Hotels in San Francisco
- Hotels with Suites in San Francisco
- Hotels with Hot Tubs in San Francisco
- Luxury Hotels in San Francisco
- Oceanfront Hotels in San Francisco
- San Francisco Hotels
- Obarrio Hotels
- Hotels near National Theater





