Cheap Flights to Santee from $166
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How Much Does it Cost To Fly To Santee?
The cheapest prices found with in the last 7 days for return flights were $222 and $166 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply
ATL
Hartsfield-Jackson Atlanta Intl.
CAE
Columbia Metropolitan
$222 Roundtrip, found 6 hours ago
$222
Roundtrip
found 6 hours ago
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DCA | West Columbia | December 2 to December 9 | $259 |
| BOS | West Columbia | September 26 to October 3 | $265 |
| ORD | West Columbia | November 6 to November 8 | $279 |
| EWR | West Columbia | October 7 to October 13 | $293 |
| EWR | West Columbia | October 7 to October 13 | $293 |
| BDL | West Columbia | September 11 to September 12 | $307 |
| JFK | West Columbia | October 7 to October 13 | $365 |
| LAX | West Columbia | September 18 to September 21 | $379 |
| PHL | West Columbia | October 28 to October 31 | $391 |
| DAL | West Columbia | October 21 to October 24 | $445 |
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| DCA | West Columbia | September 5 to September 8 | $316 |
| ORD | West Columbia | September 6 to September 7 | $333 |
| LGA | West Columbia | September 5 to September 6 | $376 |
| JFK | West Columbia | September 5 to September 6 | $396 |
| TTN | West Columbia | September 5 to September 8 | $427 |
| BDL | West Columbia | September 4 to September 6 | $439 |
| DFW | West Columbia | September 4 to September 7 | $665 |
| EWR | West Columbia | September 4 to September 7 | $667 |
| LAX | West Columbia | September 5 to September 12 | $758 |
Santee Flight Information
Traveling to | Santee |
|---|---|
Lowest Price | $222 |
Number of Airlines Serving | |
Airlines Serving | American Airlines, Delta |
Number of Daily Flights | |
Airlines with Direct Flights |
Find The Perfect Hotel For After Your Flight
Amazing Santee Accommodation Deals
Baymont by Wyndham Santee
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from Aug 30 to Aug 31
$83 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,481 reviews)
"The room was clean but dated. The door was loose and had visible damage that it had been kicked in and not replaced. The staff was great. It was a last-minute choice as my husband got sick while driving back home."
Reviewed on Aug 27, 2026
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from Aug 31 to Sep 1
$70 total
Aug 31 - Sep 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Travelodge by Wyndham Santee
9117 Old Number Six Hwy Santee SC
$64 nightly
The price is $71 total per night from Aug 30 to Aug 31
$71 total
Aug 30 - Aug 31
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (770 reviews)
"0"
Reviewed on Aug 27, 2026
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Santee/I-95
9125 Old Highway 6 Santee SC
$64 nightly
The price is $71 total per night from Sep 3 to Sep 4
$71 total
Sep 3 - Sep 4
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.8/10 (473 reviews)
"The bathroom in the room was very small. The tub would not drain properly. There was a piece on the tub that was broke. There was no shampoo in the bathroom and the piece of soap that we did have was very small. The very small pool that they had the water was green. The parking was very limited and ..."
Reviewed on Aug 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Luxury Hotels in Santee
Red Roof Inn Santee
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from Aug 31 to Sep 1
$70 total
Aug 31 - Sep 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
Comfort Inn & Suites Santee
221 Britain St Santee SC
$101 nightly
The price is $112 total per night from Sep 20 to Sep 21
$112 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,000 reviews)
"Clean room"
Reviewed on Aug 26, 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from Aug 30 to Aug 31
$83 total
Aug 30 - Aug 31
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,481 reviews)
"The room was clean but dated. The door was loose and had visible damage that it had been kicked in and not replaced. The staff was great. It was a last-minute choice as my husband got sick while driving back home."
Reviewed on Aug 27, 2026
Save an average of 15% on thousands of hotels when you're signed in
Ramada by Wyndham Santee I-95
123 Mall Street Santee SC
$69 nightly
The price is $76 total per night from Sep 8 to Sep 9
$76 total
Sep 8 - Sep 9
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a nightclub. Popular attractions Santee Cooper Country Club and Santee National ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Santee
Comfort Inn & Suites Santee
221 Britain St Santee SC
$101 nightly
The price is $112 total per night from Sep 20 to Sep 21
$112 total
Sep 20 - Sep 21
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,000 reviews)
"Clean room"
Reviewed on Aug 26, 2026
Hampton Inn Santee-I-95
9060 Old Number Six Hwy Santee SC
$123 nightly
The price is $137 total per night from Sep 7 to Sep 8
$137 total
Sep 7 - Sep 8
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,000 reviews)
"Room was dirty."
Reviewed on Aug 23, 2026
Best Western Plus Santee Inn
I 95 Exit 98 Santee SC
$111 nightly
The price is $123 total per night from Sep 6 to Sep 7
$123 total
Sep 6 - Sep 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
Save an average of 15% on thousands of hotels when you're signed in
Holiday Inn Santee by IHG
139 Bradford Blvd Santee SC
$103 nightly
The price is $114 total per night from Sep 27 to Sep 28
$114 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Best Santee Flight and Hotel Packages
Santee flight + hotel packages - economy flights
Price found within the past 48 hours. Click for updated prices.
Need a Car For After Your Flight?
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Toyota Corolla
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Plane Tickets To Santee
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When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santee to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santee without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santee with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santee today!
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