Cheap Flights to Santee from $157

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How Much Does it Cost To Fly To Santee?

The cheapest prices found with in the last 7 days for return flights were $249 and $157 for one-way flights to Santee for the period specified. Prices and availability are subject to change. Additional terms apply

OriginDestinationTravel DatesFlights From*
DCAWest ColumbiaJune 4 to June 6$255
LGAWest ColumbiaJune 1 to June 6$265
ORDWest ColumbiaJune 18 to June 22$275
EWRWest ColumbiaJuly 10 to July 13$279
BOSWest ColumbiaJuly 17 to July 25$281
JFKWest ColumbiaJune 17 to June 20$285
BDLWest ColumbiaMay 29 to June 2$313
TTNWest ColumbiaJune 20 to June 23$388
LAXWest ColumbiaJuly 6 to July 11$418
DFWWest ColumbiaJune 17 to June 20$503
*Prices include taxes and fees
OriginDestinationTravel DatesFlights From*
DCAWest ColumbiaMay 16 to May 18$380
LGAWest ColumbiaMay 16 to May 24$399
EWRWest ColumbiaMay 16 to May 24$468
TTNWest ColumbiaMay 16 to May 21$481
ORDWest ColumbiaMay 15 to May 17$509
DALWest ColumbiaMay 16 to May 30$566
JFKWest ColumbiaMay 15 to May 17$730
*Prices include taxes and fees

Santee Flight Information

Traveling to
Santee
Lowest Price
$249
Number of Airlines Serving
Airlines Serving
Delta, American Airlines
Number of Daily Flights
Airlines with Direct Flights

Find The Perfect Hotel For After Your Flight

Amazing Santee Accommodation Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from May 12 to May 13
$83 total
May 12 - May 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,469 reviews)
It was ok

Reviewed on May 10, 2026

Opens in a new windowBaymont by Wyndham Santee
Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from May 17 to May 18
$70 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.6/10 (654 reviews)
Staff was rude and the motel had roaches.

Reviewed on Apr 22, 2026

Opens in a new windowRed Roof Inn Santee
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2 out of 5
9117 Old Number Six Hwy Santee SC
$63 nightly
The price is $70 total per night from May 13 to May 14
$70 total
May 13 - May 14
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.2/10 Good! (730 reviews)
Parking lot as nice, you park right in front of your room. No bells and whistles but clean, nice shower and bed was very comfortable. Great stop and the price was right.

Reviewed on May 7, 2026

Opens in a new windowTravelodge by Wyndham Santee
Save an average of 15% on thousands of hotels when you're signed in
Super 8 by Wyndham Santee

Super 8 by Wyndham Santee

2 out of 5
9125 Old Highway 6 Santee SC
$64 nightly
The price is $71 total per night from May 17 to May 18
$71 total
May 17 - May 18
Total with taxes and fees
Book a stay at this golf motel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and Santee National ...
6.8/10 (460 reviews)
Continental waffle cereal milk, coffee, juice, honey, buns, bagels, toast Staff very helpful very tentative to your request. Small hotel, but offers a lot.

Reviewed on May 9, 2026

Opens in a new windowSuper 8 by Wyndham Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Luxury Hotels in Santee

Red Roof Inn Santee

Red Roof Inn Santee

2 out of 5
9091 Old Hwy 6 Santee SC
$63 nightly
The price is $70 total per night from May 17 to May 18
$70 total
May 17 - May 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Santee Cooper Country Club and ...
6.6/10 (654 reviews)
Staff was rude and the motel had roaches.

Reviewed on Apr 22, 2026

Opens in a new windowRed Roof Inn Santee
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
$114 nightly
The price is $126 total per night from May 27 to May 28
$126 total
May 27 - May 28
Total with taxes and fees
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,013 reviews)
The room was outdated and there was construction going on outside of our room first thing in the am. The windows were covered with plastic. And the pool was closed even though it was noted it was open and available to use. Thankfully the holiday Inn next door allowed the kids to swim there for a ...

Reviewed on May 10, 2026

Opens in a new windowComfort Inn & Suites Santee
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
$75 nightly
The price is $83 total per night from May 12 to May 13
$83 total
May 12 - May 13
Total with taxes and fees
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (1,469 reviews)
It was ok

Reviewed on May 10, 2026

Opens in a new windowBaymont by Wyndham Santee
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Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

2 out of 5
123 Mall Street Santee SC
$75 nightly
The price is $83 total per night from May 24 to May 25
$83 total
May 24 - May 25
Total with taxes and fees
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and a nightclub. Popular attractions Santee Cooper Country Club and Santee National ...
6.4/10 (558 reviews)
No, a few muffins and stale coffee.

Reviewed on May 3, 2026

Opens in a new windowRamada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
The price is $122 total per night from May 31 to Jun 1
$122 total
per night
May 31 - Jun 1
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Santee ...
8/10 Very Good! (1,013 reviews)
The room was outdated and there was construction going on outside of our room first thing in the am. The windows were covered with plastic. And the pool was closed even though it was noted it was open and available to use. Thankfully the holiday Inn next door allowed the kids to swim there for a ...

Reviewed on May 10, 2026

Opens in a new windowComfort Inn & Suites Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
The price is $132 total per night from May 25 to May 26
$132 total
per night
May 25 - May 26
Stay at this hotel in Santee. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,006 reviews)
Check-in was a breeze. The staff was really friendly. The room was clean, quiet and well a portion breakfast was very tasty. I would stay at this hotel again and again.

Reviewed on May 5, 2026

Opens in a new windowHampton Inn Santee-I-95
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
The price is $131 total per night from May 18 to May 19
$131 total
per night
May 18 - May 19
Book a stay at this business-friendly hotel in Santee. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,005 reviews)
This Best Western, while nothin fancy, is definitely a cut above other highway motels. It has everything a weary traveler could want. Really comfortable bed, a clean, decent sized bathroom with plenty of hot water and a decent breakfast with fresh fruit. It also has a good sized heated outdoor pool. ...

Reviewed on May 6, 2026

Opens in a new windowBest Western Plus Santee Inn
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Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd Santee SC
The price is $130 total per night from Jun 2 to Jun 3
$130 total
per night
Jun 2 - Jun 3
Book a stay at this golf hotel in Santee. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,003 reviews)
Have to pay

Reviewed on Apr 30, 2026

Opens in a new windowHoliday Inn Santee by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Best Santee Flight and Hotel Packages

Santee flight + hotel packages - economy flights

Price found within the past 48 hours. Click for updated prices.
Courtyard by Marriott Columbia Northeast/Fort Jackson Area
Hilton Columbia Center
Hampton Inn Columbia-Downtown Historic District
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Need a Car For After Your Flight?

Plane Tickets To Santee

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When you are ready to embark on your next big adventure, Travelocity will be right here waiting to open the doors to the garden so that you can go and smell the roses. When you decide to book and travel is entirely up to you, but don't wait too long because we have some of the best deals on the web and they won't last long. Take time to go through our huge selection of cheap flights to Santee to find the best deals that fit into your budget. If browsing on your phone while your boss isn't looking is more your thing (we promise we won't tell), consider checking out Travelocity's mobile app which allows you to take advantage of all our flights to Santee without having to compromise your work computer's search history. If you are looking to save even more, you can easily save up to $537 when you bundle one of our cheap flights to Santee with one of our hotels. So why are you waiting around? There is no better time than now to start booking that next trip. Start your search now to book one of our flights to Santee today!

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*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.