Book Hotels in Southeast Minnesota, MN
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Top Southeast Minnesota hotels

The Berkman
217 14th Ave SW, Rochester, MN
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $145 total per night from Nov 23 to Nov 24
$145 total
Nov 23 - Nov 24
Total with taxes and fees
This aparthotel features a gym and a seasonal outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a 24-hour business center, and ...
Clean,quiet,professional.
Reviewed on Oct 18, 2025

Spark by Hilton Rochester South
4165 Maine Ave SE, Rochester, MN
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Nov 2 to Nov 3
$81 total
Nov 2 - Nov 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
The room and hotel were very clean and nice. The staff was so friendly and accommodating. My daughter had appointments at mayo and the drive was 10 minutes away. Super easy to get there. They do have a shuttle service to Mayo, but we just drove. I wish that there were more breakfast options. The ...
Reviewed on Oct 20, 2025

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW, Rochester, MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Nov 1 to Nov 2
$149 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Clean hotel with a good breakfast close to Mayo Clinic
Reviewed on Oct 23, 2025

Hampton Inn Rochester-South
1755 S Broadway, Rochester, MN
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $95 total per night from Nov 15 to Nov 16
$95 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. Enjoy the hot tub and free perks like buffet breakfast and free self parking. You'll appreciate the free ...
Quick check-in, clean and dust free facility, comfortable beds, choice of pillows, spotless, bathrooms, helpful, and friendly staff an excellent breakfast choices.
Reviewed on Oct 21, 2025

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway, Rochester, MN
Fully refundable
$77 nightly
The price is $89 total per night from Nov 26 to Nov 27
$89 total
Nov 26 - Nov 27
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Staff was kind in all my interactions. Hotel was clean and well cared for. The room itself was very nice!
Reviewed on Oct 21, 2025

Express Suites Riverport Inn & Suites
900 Bruski Dr, Winona, MN
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $123 total per night from Oct 27 to Oct 28
$123 total
Oct 27 - Oct 28
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The girls that worked in the bar/restaurant did an assume job the 2 nights we had food and drinks there. It was very busy and they were friendly and hustled.
Reviewed on Oct 24, 2025

Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $147 total per night from Nov 2 to Nov 3
$147 total
Nov 2 - Nov 3
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Staff was incredible
Reviewed on Oct 22, 2025

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S, Rochester, MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $86 total per night from Nov 7 to Nov 8
$86 total
Nov 7 - Nov 8
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Clean room but lots of permanent stains on walls. Yet by far the best 2 star hotel I’ve stayed at. Need a place to crash and not worry about bugs? This is it! Look no further.
Reviewed on Oct 21, 2025

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Oct 29 to Oct 30
$149 total
Oct 29 - Oct 30
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Close to Mayo. Convenient
Reviewed on Oct 22, 2025
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See all available properties in Southeast Minnesota
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cheap Southeast Minnesota hotels

Red Carpet Inn Rochester
2214 South Broadway, Rochester, MN
$54 nightly
The price is $62 total per night from Nov 1 to Nov 2
$62 total
Nov 1 - Nov 2
Total with taxes and fees
7.6/10 Good! (528 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Southeast Minnesota hotel reviews by fellow wanderers

Express Suites Riverport Inn & Suites
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"The girls that worked in the bar/restaurant did an assume job the 2 nights we had food and drinks there. It was very busy and they were friendly and hustled."
A verified traveler stayed at Express Suites Riverport Inn & Suites
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