Book Hotels in Southeast Minnesota, MN

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Top Southeast Minnesota hotels

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4 out of 5
101 11TH Avenue SW Rochester MN
Fully refundable
$116 nightly
The price is $133 total per night from Jan 30 to Jan 31
$133 total
Jan 30 - Jan 31
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Great hotel!

Reviewed on Jan 21, 2026

Opens in a new windowEVEN Hotel Rochester - Mayo Clinic Area by IHG
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $81 total per night from Feb 1 to Feb 2
$81 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free perks ...
Amazing all around!

Reviewed on Jan 20, 2026

Opens in a new windowSpark by Hilton Rochester South
Aspen Suites

Aspen Suites

3 out of 5
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Feb 1 to Feb 2
$149 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Outdoor temps were very cold during my stay - below zero Fahrenheit. I was really pleased that underground heated parking was available when I arrived!!! My room was great. Staff very pleasant and helpful.

Reviewed on Jan 20, 2026

Opens in a new windowAspen Suites
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3 out of 5
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Jan 31 to Feb 1
$149 total
Jan 31 - Feb 1
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
All the above!! Surprisingly pleasant and exceeded expectations. Expedia value was an extra bonus.

Reviewed on Jan 18, 2026

Opens in a new windowHyatt House Rochester/Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 out of 5
220 S Broadway Rochester MN
Fully refundable
$93 nightly
The price is $107 total per night from Jan 31 to Feb 1
$107 total
Jan 31 - Feb 1
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Great room. Nice that checkout is noon. Having Crave Restaurant downstairs is great too.

Reviewed on Jan 20, 2026

Opens in a new windowHotel Indigo Rochester – Mayo Clinic Area by IHG
Treasure Island Resort and Casino

Treasure Island Resort and Casino

3 out of 5
5734 Sturgeon Lake Road Welch MN
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $107 total per night from Feb 1 to Feb 2
$107 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features a casino, a full-service spa, and a water park. Bring the family and enjoy the lazy river, children's club, and children's pool. Enjoy the ...
everything was great. They were the most helpful and cheerful of any place I have stayed in . They were truly great and that was all the staff that we dealt with, check in and the coat check..

Reviewed on Jan 20, 2026

Opens in a new windowTreasure Island Resort and Casino
Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Jan 29 to Jan 30
$146 total
Jan 29 - Jan 30
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Very friendly staff

Reviewed on Jan 20, 2026

Opens in a new windowKahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3 out of 5
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $85 total per night from Jan 30 to Jan 31
$85 total
Jan 30 - Jan 31
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Very helpful staff. Wasn't able to try breakfast due to my schedule

Reviewed on Jan 17, 2026

Opens in a new windowAmericInn by Wyndham Rochester Near Mayo Clinic
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 out of 5
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Feb 1 to Feb 2
$151 total
Feb 1 - Feb 2
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Didn't experience breakfast.

Reviewed on Jan 20, 2026

Opens in a new windowKahler Inn and Suites - Mayo Clinic Area
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Southeast Minnesota hotels

Red Carpet Inn Rochester

Red Carpet Inn Rochester

2214 South Broadway Rochester MN
$60 nightly
The price is $69 total per night from Jan 27 to Jan 28
$69 total
Jan 27 - Jan 28
Total with taxes and fees
7.6/10 Good! (535 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Southeast Minnesota hotel reviews by fellow wanderers

Brentwood Inn & Suites

Brentwood Inn & Suites

5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Everything about Brentwood was convenient. The evening desk clerk was friendly and very helpful. The parking was easy. With all the roads closed around Mayo, they allowed me to keep my vehicle in the ramp for hours past check-out. The staff cleaning the rooms was very helpful. As I stepped into the hall, I realized I had left my key inside. The man who was in the room across the hall saw it and was kind enough to open the door for me so I didn't need to go to the front desk. I would definitely stay there again. The room was very quiet, and there is a tunnel which takes you all across the Mayo campus without going outside. "
A verified traveler stayed at Brentwood Inn & Suites
Brentwood Inn & Suites

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