Deals on vacations and trips to Santee

Save when you book Santee package deals

Choose two or more items and save on your trip:

Santee flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
Seven Oaks
Save 100% on your flight
Price was $300, price is now $187 per person
$187
per person
Feb 19 - Feb 23
found 18 hours ago
Roundtrip flight included
Boston (BOS) to Columbia (CAE)
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling for business? Take advantage of the business center, express check-in, and conference space. There's a gym on site, and a 24-hour front desk and a snack bar/deli are also provided.
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
Downtown Columbia
Save 100% on your flight
Price was $666, price is now $438 per person
$438
per person
Feb 19 - Feb 23
found 18 hours ago
Roundtrip flight included
Boston (BOS) to Columbia (CAE)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and free internet in public areas. Self parking, a terrace, and a lobby fireplace are also offered.
Hilton Columbia Center

Hilton Columbia Center

3.5 out of 5
Downtown Columbia
Save 100% on your flight
Price was $1,146, price is now $779 per person
$779
per person
Feb 19 - Feb 23
found 18 hours ago
Roundtrip flight included
Boston (BOS) to Columbia (CAE)
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a 24-hour gym on site, and laundry facilities and concierge services are also offered.
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
Save 100% on your flight
Price was $456, price is now $320 per person
$320
per person
Feb 19 - Feb 23
found 18 hours ago
Roundtrip flight included
Boston (BOS) to Columbia (CAE)
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and free airport shuttle. Enjoy the seasonal outdoor pool and perks like free self parking.
Chesnut Cottage Inn Bed & Breakfast

Chesnut Cottage Inn Bed & Breakfast

3 out of 5
Downtown Columbia
Save 100% on your flight
Price was $729, price is now $511 per person
$511
per person
Jan 28 - Feb 1
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Columbia (CAE)
This bed & breakfast features free WiFi in public areas, wedding services, and free self parking. Enjoy the free full breakfast each morning. A communal living room and a library are also provided.

Top Santee hotels deals

Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Free Cancellation
Reserve now, pay when you stay
$96 nightly
The price is $107 total per night
$107 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
This hotel features an indoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Staff at the 24-hour front desk can provide around-the-clock assistance.
Pool
Breakfast included
Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Free Cancellation
Reserve now, pay when you stay
$71 nightly
The price is $79 total per night
$79 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Traveling on business? Take advantage of the express check-in and free internet in public areas. There's express check-out and multilingual staff can provide around-the-clock assistance.
Breakfast included
Pet friendly
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 out of 5
9074 Old Number Six Hwy Santee SC
$121 nightly
The price is $134 total per night
$134 total
Dec 18 - Dec 19
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a snack bar/deli, and a picnic area are also on offer.
Pool
Breakfast included
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

2.5 out of 5
9060 Old Number Six Hwy Santee SC
Free Cancellation
Reserve now, pay when you stay
$112 nightly
The price is $124 total per night
$124 total
Dec 23 - Dec 24
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. A 24-hour business center, a terrace, and laundry facilities are also on offer.
Pool
Breakfast included
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

3 out of 5
139 Bradford Blvd Santee SC
Free Cancellation
$104 nightly
The price is $115 total per night
$115 total
Dec 14 - Dec 15
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the 24-hour gym and perks like free self parking.
Pool
Pet friendly
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 out of 5
221 Britain St Santee SC
Free Cancellation
Reserve now, pay when you stay
$103 nightly
The price is $114 total per night
$114 total
Dec 21 - Dec 22
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, a lobby fireplace, and laundry facilities are also on offer.
Pool
Breakfast included
Don't see what you're looking for?
See all available properties in Santee
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Santee State Park

4/5(43 reviews)

You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.

Santee State Park

Santee Cooper Country Club

4/5(12 reviews)

Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.

Santee Cooper Country Club

Santee National Golf Club

3.5/5(19 reviews)

Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.

Santee National Golf Club

Frequently asked questions

How much are vacation packages to Santee?
With vacation packages available from as little as $187, it's not necessary to drain your bank balance for your getaway to Santee. Travelocity can help. Bundle your hotels, flights and tours into a package and walk away with fantastic discounts. The more you book, the more you save.
How long should my Santee vacation be?
Most visitors stay in Santee for approximately 2 nights. That said, travel is all about trying out new things and making memories — why not stay a couple of extra nights so you can do just that?
Where can I get the best vacation package deals for Santee?
One word — Travelocity. With as many as 400 air carriers and 1,000,000 properties worldwide, it's easy to find a Santee package deal that suits your needs.
Why should I book my Santee vacation bundle via Travelocity?
Whether you're planning a month-long vacation or a last-minute trip, we have many alluring destinations to choose from at an affordable price. And on top of that, we offer support 24/7, superb service and a Price Match Guarantee. Save yourself the effort and time and book your dream vacation today.
Can I save on my Santee car rental if I combine it with my hotel or flight?
You sure can with our Santee vacation packages. With one of these, there are lots of ways to make your travel budget go further. Combine any two or more car, hotel, flight and tour bookings and watch your savings grow. With a rental car, all the popular attractions around Santee are an unforgettable road trip away.
What is there to do in Santee?
Santee is full of places to explore, such as Santee State Park and Santee Cooper Country Club. These two popular attractions are on most travelers' itineraries.
Where should I stay when visiting Santee?
The Baymont by Wyndham Santee is the number one choice of many visitors. Book soon before it's too late.

Photos of local treasures

Browse Santee vacation photos for more inspiration

Santee

Explore More Ways to Travel with Travelocity