Book Hotels in La Mesilla, NM
Cabins, apartments, houseboats! We offer comfortable & private vacation rentals
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Top La Mesilla hotels

Bishop's Lodge, Auberge Collection
1297 Bishops Lodge Rd, Santa Fe, NM
$854 nightly
The price is $955 total per night from Sep 28 to Sep 29
$955 total
Sep 28 - Sep 29
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free resort. There's fun for all ages with a children's club and horse riding/rentals, ...
"This hotel is set on the mountain and has most incredible views, gardens, people, service, food and amenities. It's pricey but it was so worth it to me. My mission of total decompression was accomplished."
Reviewed on Sep 20, 2025

Four Seasons Resort Rancho Encantado Santa Fe
198 State Road 592, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$710 nightly
The price is $794 total per night from Oct 22 to Oct 23
$794 total
Oct 22 - Oct 23
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury resort. Families will appreciate the onsite laundry facilities, kid-friendly ...
"Food options were good, but limited. The scenery was breathtaking as well as the nearby Santa Fe and the tours we took to the Indian reservation and Los Alamos"
Reviewed on Jul 29, 2025

Homewood Suites by Hilton Santa Fe-North
10 Buffalo Thunder Trail, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $174 total per night from Oct 19 to Oct 20
$174 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Free perks ...
"Kitchen easy walking to casino breakfast was fantastic friendly"
Reviewed on Sep 22, 2025

Hampton Inn & Suites Los Alamos White Rock
124 State Hwy 4, Los Alamos, NM
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $128 total per night from Oct 18 to Oct 19
$128 total
Oct 18 - Oct 19
Total with taxes and fees
This hotel features a gym and a sauna. There's no skimping on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. A business center, ...
A Nice Hotel near the Lab
"This was a good situation for me to stay in while I was waiting for my son to finish up his internship at the lab. I liked the hotel on the other side of Los Alamos just a little bit better, but this one was not bad at all. The coffee was quite good, which is an essential for me, and they had non-dairy ..."
Reviewed on Sep 18, 2025

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG
60 Entrada Dr, Los Alamos, NM
Fully refundable
$122 nightly
The price is $137 total per night from Oct 23 to Oct 24
$137 total
Oct 23 - Oct 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Honestly, the only negative was how noisy the other guests were. Other than that, great!"
Reviewed on Sep 12, 2025

Hilton Santa Fe Buffalo Thunder
20 Buffalo Thunder Trl, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$121 nightly
The price is $138 total per night from Oct 13 to Oct 14
$138 total
Oct 13 - Oct 14
Total with taxes and fees
This smoke-free resort features a golf course, a casino, and a full-service spa. There's fun for all ages with a children's pool and an arcade/game room, and ...
Best Stay
"This is one of my favorite hotel stays of all time top-notch customer service. Everything was clean. The room was spacious and the bed was comfortable. We absolutely loved our balcony and enjoyed looking out at the sky at night. I highly recommend this hotel."
Reviewed on Sep 21, 2025

Cities Of Gold Casino
10-A Cities of Gold Road, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $96 total per night from Oct 26 to Oct 27
$96 total
Oct 26 - Oct 27
Total with taxes and fees
A casino and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
"Staff could’ve been friendlier. Otherwise a good place to stay for one night."
Reviewed on Sep 20, 2025

Wingate by Wyndham Los Alamos
2455 Trinity Dr, Los Alamos, NM
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $133 total per night from Oct 19 to Oct 20
$133 total
Oct 19 - Oct 20
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
"Was great minus very small parking lot. Didn’t have fresh towels, drains didn’t drain well, no shampoo"
Reviewed on Sep 21, 2025

Hotel Glorieta
750 N. St Francis Dr, Santa Fe, NM
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $166 total per night from Sep 28 to Sep 29
$166 total
Sep 28 - Sep 29
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and a 24-hour gym. Traveling on business? Take advantage of the 3 conference rooms, along with the 24-hour ...
"Very close to the Opera in Santa Fe and also close to the downtown incredible place to stay at an affordable price"
Reviewed on Sep 21, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent La Mesilla hotel reviews by fellow wanderers

Homewood Suites by Hilton Santa Fe-North
5 out of 5
Posted 4 days ago
Travelocity Verified Review
"Kitchen easy walking to casino breakfast was fantastic friendly "
A verified traveler stayed at Homewood Suites by Hilton Santa Fe-North
Explore More Ways to Travel with Travelocity
Explore More Ways to Travel with Travelocity
Accommodation Types
An Attraction
- Hotels near Ski Santa Fe
- Hotels near Santa Fe Opera
- Hotels near Bandelier National Monument
- Hotels near Rio Grande
- Hotels near Nambe Falls
- Hotels near Carson National Forest
- Hotels near Santuario de Chimayo
- Hotels near Cities of Gold Casino
- Hotels near Lowlows Lowrider Art Place
- Hotels near Los Alamos Historical Museum
- Hotels near Santa Fe National Cemetery
- Hotels near Puye Cliff Dwellings
- Hotels near Pajarito Ski Mountain
- Hotels near Rio Chama
- Hotels near Towa Golf Resort
- Hotels near Las Campanas Santa Fe
- Hotels near Bradbury Science Museum
- Hotels near Chimayo Trading and Mercantile
- Hotels near Black Mesa Winery
- Hotels near Casa Cristal Pottery
- Hotels near Don Quixote Distillery & Winery
- Hotels near Oviedo Carvings and Bronze Gallery
- Santa Fe Hotels
- Los Alamos Hotels
- Jemez Springs Hotels
- Espanola Hotels
- Abiquiu Hotels
- Rocky Mountains Hotels
- Ojo Caliente Hotels
- El Rito Hotels
- Chimayo Hotels
- Ohkay Owingeh Hotels
- Northern New Mexico Hotels
- Western United States Hotels
- Southern Rocky Mountains Hotels
- Pojoaque Hotels
- White Rock Hotels
- Embudo Hotels
- Truchas Hotels
- Cuyamungue Hotels
- Alcalde Hotels
- Hernandez Hotels
- Medanales Hotels
- Velarde Hotels
- Santa Cruz Hotels
- Santa Fe National Forest Hotels
- Nambe Hotels
- Sangre de Cristo Mountains Hotels
- La Puebla Hotels
- El Valle de Arroyo Seco Hotels
- Cordova Hotels
- Trampas Hotels
- San Juan Pueblo Hotels
- San Ildefonso Pueblo Hotels
- North Central New Mexico Hotels
- Central New Mexico Hotels
- Rio en Medio Hotels
Most popular
Hotels
Flights
- Virgin Atlantic London (LHR) to Seattle (SEA) flights
- Frontier Airlines Las Vegas (LAS) to Florence (CVG) flights
- Phoenix to Atlanta (PHX - ATL)
- American Airlines Chicago (ORD) to Key West (EYW) flights
- Cheap Flights to Delaware
- Air France Santa Ana (SNA) to Paris (CDG) flights
- Air Transat Toronto (YYZ) to Orlando (MCO) flights
- American Airlines El Paso (ELP) to New York (LGA) flights
- United Tampa (TPA) to Traverse City (TVC) flights
- Boston to Amsterdam (BOS - AMS)
- Hawaiian Airlines Sacramento (SMF) to Kailua-Kona (KOA) flights
- American Airlines Beef Island (EIS) to Miami (MIA) flights
- Charlotte to Cairo (CLT - CAI)
- Chicago to Chicago (MDW - ORD)
- Wilkes-Barre to Jacksonville (AVP - JAX)
Packages