Book Hotels in La Mesilla, NM

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Top La Mesilla hotels

Four Seasons Resort Rancho Encantado Santa Fe

Four Seasons Resort Rancho Encantado Santa Fe

5 out of 5
198 State Road 592 Santa Fe NM
$717 nightly
The price is $803 total per night from Oct 28 to Oct 29
$803 total
Oct 28 - Oct 29
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury resort. Families will appreciate the onsite laundry facilities, kid-friendly ...
"Rancho Encantado is the ultimate Southwestern getaway. The property is stunning, nestled quietly in the foothills away from the downtown noise. Having a private patio and cozy wood-burning fireplace made our casita feel like a home away from home. Impeccable Four Seasons service throughout. Highly ..."

Reviewed on Sep 30, 2026

Opens in a new windowFour Seasons Resort Rancho Encantado Santa Fe
Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

4 out of 5
20 Buffalo Thunder Trl Santa Fe NM
Fully refundableReserve now, pay when you stay
$212 nightly
The price is $243 total per night from Oct 21 to Oct 22
$243 total
Oct 21 - Oct 22
Total with taxes and fees
This smoke-free resort features a golf course, a casino, and a full-service spa. There's fun for all ages with a children's pool and an arcade/game room, and ...
"I was surprised by the poor condition of the hotel rooms. We had to leave our first room upon check-in because there was a very loud noise that was attributed to the boiler. That room did not appear well-cleaned with sticky countertops and mold in the bathroom. Our second room did not have the same ..."

Reviewed on Oct 1, 2026

Opens in a new windowHilton Santa Fe Buffalo Thunder
Wingate by Wyndham Los Alamos

Wingate by Wyndham Los Alamos

3 out of 5
2455 Trinity Dr Los Alamos NM
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $175 total per night from Oct 31 to Nov 1
$175 total
Oct 31 - Nov 1
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the 24-hour ...
"We enjoyed our stay here - the rooms were nice and super clean. Sophie (Sophia?) at the front desk was super friendly and helpful. Breakfast was excellent. A very good value hotel!"

Reviewed on Sep 30, 2026

Opens in a new windowWingate by Wyndham Los Alamos
Cities Of Gold Casino

Cities Of Gold Casino

3 out of 5
10-A Cities of Gold Road Santa Fe NM
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $77 total per night from Oct 11 to Oct 12
$77 total
Oct 11 - Oct 12
Total with taxes and fees
A casino and a restaurant are featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowCities Of Gold Casino
Hotel Glorieta

Hotel Glorieta

3.5 out of 5
750 N. St Francis Dr Santa Fe NM
Fully refundableReserve now, pay when you stay
$146 nightly
The price is $168 total per night from Oct 26 to Oct 27
$168 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 3 conference rooms, along with the 24-hour business ...
Opens in a new windowHotel Glorieta
Bishop's Lodge, Auberge Collection

Bishop's Lodge, Auberge Collection

5 out of 5
1297 Bishops Lodge Rd Santa Fe NM
$954 nightly
The price is $1,067 total per night from Oct 22 to Oct 23
$1,067 total
Oct 22 - Oct 23
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free resort. There's fun for all ages with a children's club and horse riding/rentals, ...
Opens in a new windowBishop's Lodge, Auberge Collection
Ohkay Casino Resort Hotel

Ohkay Casino Resort Hotel

2.5 out of 5
Highway 68 Ohkay Owingeh NM
$109 nightly
The price is $121 total per night from Oct 4 to Oct 5
$121 total
Oct 4 - Oct 5
Total with taxes and fees
This hotel features a casino, a nightclub, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Opens in a new windowOhkay Casino Resort Hotel
The Inn at the Delta

The Inn at the Delta

3 out of 5
243 N Paseo de Onate Espanola NM
$132 nightly
The price is $150 total per night from Oct 19 to Oct 20
$150 total
Oct 19 - Oct 20
Total with taxes and fees
This bed & breakfast doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, express check-out, and concierge services are also ...
Opens in a new windowThe Inn at the Delta
Rodeway Inn Española

Rodeway Inn Española

2 out of 5
604-B S. Riverside Dr. Espanola NM
Fully refundable
$60 nightly
The price is $68 total per night from Oct 30 to Oct 31
$68 total
Oct 30 - Oct 31
Total with taxes and fees
A restaurant and free WiFi in public areas are featured at this hotel. Guests will appreciate freebies like continental breakfast and free self parking. Staff ...
Opens in a new windowRodeway Inn Española
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the top kid-friendly hotels in La Mesilla?
From unique amenities to extra space, kid-friendly hotels come with features that can help turn a regular family vacation into an awesome one. These La Mesilla options make getting away with little ones child's play: Your gang will enjoy their time at Motel 6 Espanola, NM. Pet-friendly facilities and front desk services are a few of the things that help make this hotel a sought-after option. Days Inn by Wyndham Espanola is also a great choice. After a big day of exploring La Mesilla, return to your cozy room and amenities like complimentary breakfast and a memory foam mattress.
Where can I find cheap hotels in La Mesilla?
At Travelocity you'll find really nice hotels in La Mesilla at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near La Mesilla rather than in La Mesilla. We may find you even better rates, too.
How do I find the best La Mesilla hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in La Mesilla then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in La Mesilla?
The cheapest hotel in La Mesilla is $68. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in La Mesilla?
There are 392 hotels in La Mesilla on Travelocity.
What are the best hotels in La Mesilla?
La Mesilla has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in La Mesilla for you!
When is the best time to visit La Mesilla?
If you want the joy of a fun-filled trip in peak season, visit La Mesilla during August, September and October. If you'd prefer the peace of off-season, book a stay during quieter months, such as February, November and December.
When is the cheapest time to stay in La Mesilla?
Based on historic data is usually the cheapest month to visit La Mesilla. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in La Mesilla?
There are multiple hotels in La Mesilla that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to La Mesilla. We have plenty of kid-friendly hotels in La Mesilla to choose from on Travelocity!
Why book a hotel in La Mesilla through Travelocity?
Because we have the top hotels in La Mesilla! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in La Mesilla on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent La Mesilla hotel reviews by fellow wanderers

Wingate by Wyndham Los Alamos

Wingate by Wyndham Los Alamos

5 out of 5
Posted 15 hours ago
Travelocity Verified Review
"We enjoyed our stay here - the rooms were nice and super clean. Sophie (Sophia?) at the front desk was super friendly and helpful. Breakfast was excellent. A very good value hotel!"
A verified traveler stayed at Wingate by Wyndham Los Alamos
Wingate by Wyndham Los Alamos

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