Explore 9 Luxury Hotels in West Main Historic District
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Best Luxury Hotels in West Main Historic District

21c Museum Hotel Louisville
Great location for Whiskey Row in Downtown Louisville. Hotel was clean, artsy and has a great restaurant on site.
Reviewed on Jan 25, 2026

Louisville Marriott Downtown
Room was spotless. Staff was top notch. Amenities as expected but I did expect a microwave in the room. There wasn't one. 9/10 experience. Will definitely book again!
Reviewed on Jan 16, 2026

Galt House Hotel Trademark Collection by Wyndham
The breakfast was delicious, the staff was amazing to be with and supper attended.
Reviewed on Jan 20, 2026

Embassy Suites Louisville Downtown
Room was spotless
Reviewed on Jan 23, 2026

Seelbach Hilton Louisville Downtown
The area was congested but the motel was good.
Reviewed on Jan 14, 2026

Hyatt Regency Louisville
Excellent
Reviewed on Jan 21, 2026

Hampton Inn Louisville Downtown
Great staff and wonderful location. Thank you!!
Reviewed on Jan 25, 2026

Econo Lodge Louisville Downtown
Nice hotel with a great location near Whiskey Row. This is my 3rd stay at this hotel and will definitely come back again
Reviewed on Dec 11, 2025
More 4 star hotels in West Main Historic District

The Grady
5 star hotels in West Main Historic District

Louisville Bourbon Inn
West Main Historic District Luxury Hotels
Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the West Main Historic District luxury hotels are the plush oasis you’ve been looking for.
Choose from the best luxury hotels in West Main Historic District to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.
We want you to enjoy your next vacation in style and the top luxury resorts in West Main Historic District will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in West Main Historic District, and plan your next opulent escape.
West Main Historic District hotels essential information
Accommodation | 2,101 hotels |
|---|---|
Lowest Price | $74 |
Highest Price | $308 |
Popular hotels | 21c Museum Hotel Louisville, Galt House Hotel Trademark Collection by Wyndham, Embassy Suites Louisville Downtown, Econo Lodge Louisville Downtown, Seelbach Hilton Louisville Downtown, Louisville Marriott Downtown, Hyatt Regency Louisville, Hampton Inn Louisville Downtown |
Popular Luxury Stays in West Main Historic District
Recent West Main Historic District Hotel Reviews By Fellow Wanderers

Embassy Suites Louisville Downtown
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