Explore top 2025 4 Star Hotels in Louisville

Name: Hotel Distil, Autograph Collection
Price range: $227 total
Rating: 9.4

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Top Louisville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$146 nightly

$172 total

Nov 22 - Nov 23

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.8/10 Excellent! (3,708 reviews)

Amazing hotel

Reviewed on Oct 18, 2025

Omni Louisville Hotel

400 S. 2nd Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$199 nightly

$234 total

Nov 15 - Nov 16

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.2/10 Wonderful! (1,650 reviews)

The hotel is beautiful and the staff was amazing from the time we checked in until we checked out definitely one of my top five hotel hotels and stays

Reviewed on Oct 18, 2025

Derby City Gaming & Hotel - A Churchill Downs Property

4520 Poplar Level Rd, Louisville, KY

Fully refundableReserve now, pay when you stay

$119 nightly

$140 total

Oct 26 - Oct 27

Total with taxes and fees

This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...

9.4/10 Exceptional! (1,527 reviews)

Very nice! Clean hotel!

Reviewed on Oct 17, 2025

Embassy Suites Louisville Downtown

501 South Fourth Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$130 nightly

$153 total

Nov 2 - Nov 3

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and WiFi in public areas. Valet ...

8.8/10 Excellent! (1,030 reviews)

Room was clean, and breakfast was very good.

Reviewed on Oct 18, 2025

The Brown Hotel

335 W Broadway, Louisville, KY

Fully refundableReserve now, pay when you stay

$168 nightly

$198 total

Oct 30 - Oct 31

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and ...

9.2/10 Wonderful! (1,112 reviews)

Came highly recommended, but did not fulfill expectations, notwithstanding appealing rate. While the hotel is a stately destination, it's current condition is tired, and borderline dilapidated. Frint desk at check-in- excellent; but night and morning team inattentive.

Reviewed on Oct 20, 2025

Hotel Genevieve part of JdV by Hyatt

730 E Market St, Louisville, KY

Fully refundableReserve now, pay when you stay

$135 nightly

$159 total

Nov 2 - Nov 3

Total with taxes and fees

This hotel features 2 restaurants and 3 bars/lounges. WiFi in public areas is free. Valet parking, a coffee shop, and a snack bar/deli are also offered.

9/10 Wonderful! (987 reviews)

Excellent

Reviewed on Oct 18, 2025

Hyatt Regency Louisville

320 West Jefferson Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$147 nightly

$173 total

Nov 17 - Nov 18

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.6/10 Excellent! (1,016 reviews)

Was good

Reviewed on Oct 18, 2025

21c Museum Hotel Louisville

700 W Main Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$165 nightly

$195 total

Oct 30 - Oct 31

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.2/10 Wonderful! (1,004 reviews)

We only stayed 1 night, but everything was excellent

Reviewed on Oct 7, 2025

The Grady

601 W Main St, Louisville, KY

Fully refundableReserve now, pay when you stay

$206 nightly

$242 total

Nov 2 - Nov 3

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.

9.2/10 Wonderful! (1,007 reviews)

Going to give a 4.8 out of five. In order for you to be a five it would be nice to have a make up mirror in the bathroom and a seat in the shower.

Reviewed on Oct 16, 2025

Hotel Distil, Autograph Collection

101 West Main Street, Louisville, KY

Fully refundableReserve now, pay when you stay

$193 nightly

$227 total

Nov 9 - Nov 10

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.4/10 Exceptional! (412 reviews)

Really a nice place to stay

Reviewed on Oct 6, 2025

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4 Star Hotels Louisville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Louisville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Louisville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Louisville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.