Explore top 2026 4 Star Hotels in East Louisville

Name: Hotel Distil, Autograph Collection
Price range: $237 total
Rating: 9.6

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Top East Louisville 4 Star hotels

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$147 nightly

$173 total

Aug 3 - Aug 4

Total with taxes and fees

A full-service spa, 4 restaurants, and a gym are all featured at this hotel. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

9/10 Wonderful! (4,171 reviews)

"Beautiful property"

Reviewed on Jul 6, 2026

Omni Louisville Hotel

400 S. 2nd Street Louisville KY

Fully refundableReserve now, pay when you stay

$179 nightly

$211 total

Jul 8 - Jul 9

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.4/10 Exceptional! (1,970 reviews)

"Amazing staff and amenities. Five star resort experience."

Reviewed on Jul 5, 2026

Derby City Gaming & Hotel - A Churchill Downs Property

4520 Poplar Level Rd Louisville KY

Fully refundableReserve now, pay when you stay

$113 nightly

$133 total

Jul 20 - Jul 21

Total with taxes and fees

This smoke-free hotel features 3 restaurants and 3 bars/lounges. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee ...

9.4/10 Exceptional! (2,319 reviews)

"Beautiful room clean clean. I didn’t get my casino credit though as stated included with room booking."

Reviewed on Jul 5, 2026

21c Museum Hotel Louisville

700 W Main Street Louisville KY

Fully refundableReserve now, pay when you stay

$156 nightly

$184 total

Jul 26 - Jul 27

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business ...

9.4/10 Exceptional! (1,002 reviews)

"I’ve always wanted to stay in a 21C hotel and I am glad I made the decision to in Louisville. Not only was the art awe inspiring, but the hotel and its staff were amazing. They were very accommodating, everything was clean and cute, and they even give you a free nightcap shot of bourbon. The location ..."

Reviewed on Jun 30, 2026

Embassy Suites Louisville Downtown

501 South Fourth Street Louisville KY

Fully refundableReserve now, pay when you stay

$122 nightly

$144 total

Jul 31 - Aug 1

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Enjoy the 24-hour gym and free perks like on-the-go breakfast and a roundtrip airport shuttle. ...

9/10 Wonderful! (1,287 reviews)

"Great place downtown able to walk to see the fireworks, Uber doesn’t know where to pick you up from. The AC doesn’t go any lower than 71 degrees!! And check the shampoo, conditioner and body wash before getting into the shower. Breakfast was ok."

Reviewed on Jul 5, 2026

Hyatt Regency Louisville

320 West Jefferson Street Louisville KY

Fully refundableReserve now, pay when you stay

$144 nightly

$169 total

Aug 1 - Aug 2

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.8/10 Excellent! (1,003 reviews)

"Beautiful Hotel!"

Reviewed on Jul 6, 2026

Louisville Marriott Downtown

280 West Jefferson Street Louisville KY

Fully refundableReserve now, pay when you stay

$168 nightly

$197 total

Aug 2 - Aug 3

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9/10 Wonderful! (1,001 reviews)

"Beautiful hotel"

Reviewed on Jul 1, 2026

The Grady

601 W Main St Louisville KY

Fully refundableReserve now, pay when you stay

$175 nightly

$206 total

Aug 2 - Aug 3

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a library are also offered.

9.4/10 Exceptional! (1,003 reviews)

"Excellent hotel with a great restaurant which adds to the experience and ambience. Feels more like a small apartment than a hotel room. Very home like feeling and very comfortable bed."

Reviewed on Jul 3, 2026

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

143 West Market St Louisville KY

Fully refundableReserve now, pay when you stay

$171 nightly

$202 total

Aug 2 - Aug 3

Total with taxes and fees

This smoke-free hotel's 2 restaurants, 3 bars/lounges, and gym are some of the featured amenities. Traveling on business? Take advantage of the business center, ...

9.4/10 Exceptional! (124 reviews)

"Great property. Love the rooftop!"

Reviewed on Jul 5, 2026

Hotel Distil, Autograph Collection

101 West Main Street Louisville KY

Fully refundableReserve now, pay when you stay

$202 nightly

$237 total

Aug 2 - Aug 3

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, ...

9.6/10 Exceptional! (479 reviews)

"Our stay at Hotel Distil in Louisville was nothing short of exceptional—truly one of the best hotel experiences we’ve ever had. From the moment we arrived, the reception team was incredibly friendly, quick, and efficient, making check-in seamless after a long day of travel. The room itself was stunning—spotlessly ..."

Reviewed on Jul 6, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels East Louisville

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in East Louisville 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in East Louisville will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in East Louisville, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.