Explore 2 Luxury Hotels in Mission District

Best Luxury Hotels in Mission District

Inn San Francisco

943 South Van Ness Avenue, San Francisco, CA

$206 nightly

$240 total

Jul 24 - Jul 25

Total includes taxes and fees

A rooftop terrace, self parking, and laundry facilities are featured at this bed & breakfast. Guests will appreciate free perks like buffet breakfast and WiFi ...

9.6/10 Exceptional! (509 reviews)

"The Inn San Francisco is a beautiful Victorian mansion in the Mission neighborhood. The roof deck and back patio are wonderful places to relax. Marty and his family are friendly and have a wealth of knowledge about the history of the inn. We will definitely be back!"

Reviewed on Jul 16, 2025

El Capitan Hotel

2361 Mission St, San Francisco, CA

This hotel features a nightclub, free WiFi in public areas, and luggage storage. A safe deposit box and laundry facilities are also provided.

Horror hotel

"Did not understand the concept of a service dog. The lady working there was very rude about everything especially the service dog concept. The stairs going up were totally wet and our service dog slipped and rolled down about 5 steps and management did not show any concern. Small room with no television ..."

Reviewed on Dec 6, 2022

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More 4 star hotels in Mission District

Grand Hyatt at SFO

55 S McDonnell Rd, San Francisco, CA

$278 nightly

$311 total

Aug 4 - Aug 5

Total includes taxes and fees

9.6/10 Exceptional! (1,381 reviews)

5 star hotels in Mission District

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco, CA

$354 nightly

$417 total

Aug 22 - Aug 23

Total includes taxes and fees

9.2/10 Wonderful! (1,000 reviews)

Mission District Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Mission District luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Mission District to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Mission District will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Mission District, and plan your next opulent escape.