Book Hotels in Byron, MN
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Top Byron hotels

The Berkman
217 14th Ave SW Rochester MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Feb 20 to Feb 21
$151 total
Feb 20 - Feb 21
Total with taxes and fees
This aparthotel features a gym and a seasonal outdoor pool. Enjoy the a rooftop terrace and perks like free WiFi. Self parking, a 24-hour business center, and ...
Everything was excellent, second time staying there.
Reviewed on Jan 25, 2026

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
$97 nightly
The price is $112 total per night from Feb 20 to Feb 21
$112 total
Feb 20 - Feb 21
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
The soap dispensers are actually LOCKED INTO the wall and impossible to access. How can you have a bathroom with inaccessible soap? Very poorly planned!
Reviewed on Feb 17, 2026

Aspen Suites
1211 2nd Street Rochester MN
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $149 total per night from Feb 19 to Feb 20
$149 total
Feb 19 - Feb 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
The food and staff were awesome. It was also nice to have underground parking in the winter.
Reviewed on Feb 15, 2026

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $151 total per night from Feb 21 to Feb 22
$151 total
Feb 21 - Feb 22
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Very nice staff rooms were great
Reviewed on Feb 16, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Fully refundable
$95 nightly
The price is $110 total per night from Mar 5 to Mar 6
$110 total
Mar 5 - Mar 6
Total with taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
The room was clean, bed was comfortable, and location was great.
Reviewed on Feb 17, 2026

Holiday Inn Express Rochester South - Mayo Area by IHG
4141 Maine Avenue SE Rochester MN
Fully refundable
$75 nightly
The price is $87 total per night from Feb 20 to Feb 21
$87 total
Feb 20 - Feb 21
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
Clean rooms, great staff, excellent breakfast
Reviewed on Feb 15, 2026

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $146 total per night from Feb 19 to Feb 20
$146 total
Feb 19 - Feb 20
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Another great stay at the Kahler Grand Hotel. Its right across the street from the Mayo. Staff is excellent at the Kahler always very helpful.
Reviewed on Feb 18, 2026

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $86 total per night from Mar 1 to Mar 2
$86 total
Mar 1 - Mar 2
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public ...
Staff was friendly and the hotel/room were clean. Had a pool, kids pool and hot tub along with a spa. Had a restaurant onsite and offered continental breakfast, which had good options.
Reviewed on Feb 15, 2026

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $152 total per night from Feb 19 to Feb 20
$152 total
Feb 19 - Feb 20
Total with taxes and fees
This hotel features an indoor pool and a gym. Business travelers can take advantage of the free WiFi in public areas. Enjoy the free self-serve breakfast each ...
Very clean room. Nice breakfasts…
Reviewed on Feb 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Byron with star-rating
Check Byron Hotels by Star Rating

4 Star Hotels
2 properties

3 Star Hotels
42 properties
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Recent Byron hotel reviews by fellow wanderers

EVEN Hotel Rochester - Mayo Clinic Area by IHG
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Great room and location"
A verified traveler stayed at EVEN Hotel Rochester - Mayo Clinic Area by IHG
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