Explore top 2025 5 Star Hotels in Palo Alto

Name: Clement Palo Alto – All-Inclusive Urban Resort
Price range: $882 total
Rating: 9.8

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Top Palo Alto 5 Star hotels

Shashi Hotel Mountain View Palo Alto

1625 N Shoreline Blvd, Mountain View, CA

Fully refundableReserve now, pay when you stay

$168 nightly

$185 total

Oct 24 - Oct 25

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9.2/10 Wonderful! (1,088 reviews)

"very nice hotel. We stayed for a very short time due to a hospital visit but place was very comfortable"

Reviewed on Oct 18, 2025

Four Seasons Hotel Silicon Valley at East Palo Alto

2050 University Ave, East Palo Alto, Palo Alto, CA

Fully refundableReserve now, pay when you stay

$428 nightly

$487 total

Oct 26 - Oct 27

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the express check-in, ...

9.2/10 Wonderful! (658 reviews)

"Nice one"

Reviewed on Sep 16, 2025

Rosewood Sand Hill

2825 Sand Hill Road, Menlo Park, CA

Fully refundableReserve now, pay when you stay

$942 nightly

$1,065 total

Nov 1 - Nov 2

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Enjoy the gym and perks like free WiFi and a free area shuttle. ...

9.4/10 Exceptional! (270 reviews)

"I had a very enjoyable massage at the spa followed by the steam room. I swam laps in the pool and it was heated perfectly to 82 degrees. Food in the restaurant was tasty and service was impeccable. Although you can hear the noise from cars once inside my room it was completely quiet."

Reviewed on Oct 4, 2025

Nobu Hotel Palo Alto

180 Hamilton Ave, Palo Alto, CA

Fully refundableReserve now, pay when you stay

$395 nightly

$457 total

Oct 31 - Nov 1

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas and valet parking. A terrace ...

9/10 Wonderful! (423 reviews)

"Very clean with a smart toilet!"

Reviewed on Oct 6, 2025

Clement Palo Alto – All-Inclusive Urban Resort

711 El Camino Real, Palo Alto, CA

Fully refundableReserve now, pay when you stay

$763 nightly

$882 total

Oct 24 - Oct 25

Total with taxes and fees

A restaurant and a gym are featured at this hotel. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests ...

9.8/10 Exceptional! (107 reviews)

Amazing experience

"Everything was top of the line here. All of the staff were very friendly and helpful. We want to give a special shout out to the afternoon and evening staff working on Saturday, June 29, 2025! They went way above and beyond to make our visit a wonderful experience! My granddaughter especially loved ..."

Reviewed on Jun 29, 2025

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Palo Alto Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Palo Alto to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Palo Alto 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Palo Alto before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.