Explore top 2026 5 Star Hotels in Causeway Islands

Name: The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Price range: $288 total
Rating: 9.6

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Top Causeway Islands 5 Star hotels

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Fully refundableReserve now, pay when you stay

$138 nightly

$151 total

May 26 - May 27

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (5,415 reviews)

The best experience! Thank you!

Reviewed on May 10, 2026

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama

Fully refundableReserve now, pay when you stay

$263 nightly

$289 total

Jun 5 - Jun 6

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...

9/10 Wonderful! (1,003 reviews)

Un poco decepcionado del waldorf la verdad, todo se ve muy antiguo, muebles, facilidades, cuarto, lobby, restaurante. Digamos que uno se siento en un hilton de media gama y bo en la marca mas prestigiosa de hilton. Obviamente es muy barrato comparado con los waldor astoria de otras partes pero ahora ...

Reviewed on May 5, 2026

JW Marriott Panama

Calle Punta Colon, Punta Pacifica Panama City Panama

$255 nightly

$281 total

Jun 6 - Jun 7

Total with taxes and fees

This luxury hotel features 3 restaurants, 4 outdoor pools, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...

9/10 Wonderful! (1,018 reviews)

Beautiful outdoor pool

Reviewed on May 8, 2026

Hyatt Regency Panama City

Calle 52 and Ricardo Arias Panama City Panamá Province

Fully refundableReserve now, pay when you stay

$158 nightly

$173 total

May 31 - Jun 1

Total with taxes and fees

This luxury hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, laundry ...

9.6/10 Exceptional! (304 reviews)

This property was amazing. It was perfectly located in the city, clean, modern and had amazing amenities. No complaints.

Reviewed on May 10, 2026

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste, San Felipe Panama City Panama

Fully refundableReserve now, pay when you stay

$302 nightly

$332 total

Jun 5 - Jun 6

Total with taxes and fees

A full-service spa, 2 restaurants, and an outdoor pool are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...

9.8/10 Exceptional! (646 reviews)

This hotel is amazing. The property, the pool, the staff and service all exceeded my expectations. I wouldn’t stay anywhere else.

Reviewed on May 9, 2026

W Panama

Calle Aquilino de la Guardia & Calle 50 Panama City

Fully refundableReserve now, pay when you stay

$249 nightly

$274 total

May 17 - May 18

Total with taxes and fees

This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...

9/10 Wonderful! (1,005 reviews)

We booked the Supreme Room and it was amazing! It had a great view and was very spacious. Upon arrival, the staff was so nice and helpful. They provided us with suggestions on where to go to eat, party and sightsee. They were always available if we had questions too. The location was close to everything ...

Reviewed on May 4, 2026

The Westin Playa Bonita Panama

Km 6 Road to Veracruz Veracruz Panama

Fully refundableReserve now, pay when you stay

$202 nightly

$222 total

Jun 1 - Jun 2

Total with taxes and fees

This luxury hotel features a private beach, a full-service spa, and 4 restaurants. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. There's ...

8/10 Very Good! (1,003 reviews)

Friendly staff,great accomadations . Very relaxing. I will go back.

Reviewed on May 7, 2026

Renaissance Panama City Hotel

Via España & Ricardo Arias Street Panama City Panama

Fully refundableReserve now, pay when you stay

$127 nightly

$140 total

May 16 - May 17

Total with taxes and fees

A casino and an outdoor pool are featured at this luxury hotel. Families will appreciate the arcade/game room, onsite laundry facilities, and in-room childcare. ...

8.8/10 Excellent! (210 reviews)

Great customer service very nice lady cleaning the room, always wished me and leaving “have a good day notes” and keeping the room super clean. Her name is Dalia! I will certainly return to Renaissance Hotel 😀

Reviewed on May 8, 2026

Hilton Panama

Balboa Ave. and Aquilino De La Guardia Panama City

Fully refundableReserve now, pay when you stay

$229 nightly

$252 total

Jun 7 - Jun 8

Total with taxes and fees

This luxury hotel features an attached winery, a casino, and a full-service spa. Families will appreciate the onsite laundry facilities and babysitting. Enjoy ...

9/10 Wonderful! (1,006 reviews)

First class hotel in downtown with excellent view from pool and restaurant area on high floor (really pleasant at night). Many dining options and not far from Panama Canal and old city.

Reviewed on Apr 30, 2026

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Santa Maria Boulevard Panama City

Fully refundableReserve now, pay when you stay

$262 nightly

$288 total

Jun 5 - Jun 6

Total with taxes and fees

This luxury hotel features a golf course, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

9.6/10 Exceptional! (694 reviews)

Perfect

Reviewed on May 8, 2026

Don't see what you're looking for?

See all available properties in Causeway Islands

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Causeway Islands Resorts & 5 Star Hotels

Looking for your own little slice of heaven during your next trip? Check out all the best 5-star hotels in Causeway Islands to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the 5-star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Causeway Islands 5-star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5-star hotels in Causeway Islands before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Causeway Islands hotel reviews by fellow wanderers

Radisson Hotel Panama Canal

3 out of 5

Posted 1 hour ago

Travelocity Verified Review

"The hotel must of been a beauty in its day. The location and views of the canal were amazing. I feel as if I was treated as a second class guest because I booked through hotels.com. Our room was close to unsalable, needed lots of maintenance. Couldn’t adjust temperature, yes I did ask for assistance he couldn’t help. Got lots of no’s with nice smiles. Wanted it to be great, it was mediocre."

A verified traveler stayed at Radisson Hotel Panama Canal