Explore top 2026 4 Star Hotels in Panama City

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Top Panama City 4 Star hotels

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$142 nightly
The price is $156 total per night from Jun 30 to Jul 1
$156 total
Jun 30 - Jul 1
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
8.6/10 Excellent! (2,588 reviews)
"Nice hotel. Close to airport with convienent shutttle to and from airport. Great restaurant on property with great staff. Check in staff were extremely friendly and helpful."

Reviewed on Jun 9, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $156 total per night from Jun 14 to Jun 15
$156 total
Jun 14 - Jun 15
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center ...
9/10 Wonderful! (1,036 reviews)
"Loved how central this location is and amazing the staff is, always willing to help and happy to serve"

Reviewed on Jun 9, 2026

Opens in a new windowLas Americas Golden Tower Panama
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $125 total per night from Jun 27 to Jun 28
$125 total
Jun 27 - Jun 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,000 reviews)
"Rooms and property were clean. Next to Multiplaza Mall with easy access to food. Close proximity to popular tourist attractions."

Reviewed on Jun 9, 2026

Opens in a new windowCourtyard by Marriott Panama Multiplaza Mall
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $129 total per night from Jun 29 to Jun 30
$129 total
Jun 29 - Jun 30
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
7.8/10 Good! (1,006 reviews)
"El gym súper malo viejo sin nada"

Reviewed on Jun 4, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $149 total per night from Jun 10 to Jun 11
$149 total
Jun 10 - Jun 11
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
9/10 Wonderful! (961 reviews)
"Very friendly staff and excellent customer service from registration to housekeeping staff, including those who greet you at the door."

Reviewed on Jun 8, 2026

Opens in a new windowWaymore Hotel Spa & Casino
MARINN PLACE Financial District

MARINN PLACE Financial District

4.5 out of 5
C. Aquilino de la Guardia Panama City Panamá Province
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Jun 28 to Jun 29
$93 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (377 reviews)
"Well-maintained, good breakfast, helpful staff, good central location, free parking"

Reviewed on Jun 9, 2026

Opens in a new windowMARINN PLACE Financial District
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $115 total per night from Jul 4 to Jul 5
$115 total
Jul 4 - Jul 5
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9/10 Wonderful! (1,012 reviews)
"Breakfast was not good"

Reviewed on Jun 9, 2026

Opens in a new windowCourtyard by Marriott Panama Metromall
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $139 total per night from Jun 19 to Jun 20
$139 total
Jun 19 - Jun 20
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9.6/10 Exceptional! (1,236 reviews)
"Well located hotel, close to good restaurants walking distance. Very comfortable rooms, parking accesible and helpful staff. Great stay."

Reviewed on Jun 9, 2026

Opens in a new windowRamada Plaza by Wyndham Panama Punta Pacifica
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from Jul 3 to Jul 4
$148 total
Jul 3 - Jul 4
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
8.6/10 Excellent! (1,000 reviews)
"Friendly staff, everyone helpful"

Reviewed on Jun 9, 2026

Opens in a new windowSheraton Grand Panama
Studio Coliving

Studio Coliving

4.5 out of 5
Av. Ricardo Arango y, Av. Federico Boyd Panama City Panama
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
7.8/10 Good! (590 reviews)
"Clean, reasonable pricing. Staff was excellent, very responsive. Highly reccomend staying here"

Reviewed on Mar 26, 2026

Opens in a new windowStudio Coliving
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4 Star Hotels Panama City

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Panama City 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Panama City will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Panama City, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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