Explore top 2026 4 Star Hotels in Uptown

Name: The Cincinnatian Hotel Curio Collection by Hilton
Price range: $175 total
Rating: 7.8

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Top Uptown 4 Star hotels

Hilton Cincinnati Netherland Plaza

35 W 5th St Cincinnati OH

$127 nightly

$151 total

Jul 20 - Jul 21

Total with taxes and fees

This smoke-free hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...

8/10 Very Good! (1,620 reviews)

Reviewed on Jul 13, 2026

The Westin Cincinnati

21 E 5th St Cincinnati OH

Fully refundableReserve now, pay when you stay

$152 nightly

$181 total

Aug 6 - Aug 7

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling for business? Take advantage of the business center, express check-out, and conference space. ...

8.6/10 Excellent! (1,405 reviews)

"room was as advertised, no working ice machines, breakfast area was disappointing, the display for the menu was not working and the staff did not acknowledge us while we were standing there waiting to be helped"

Reviewed on Jul 13, 2026

21c Museum Hotel Cincinnati

609 Walnut St Cincinnati OH

Fully refundableReserve now, pay when you stay

$165 nightly

$197 total

Aug 2 - Aug 3

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...

8.6/10 Excellent! (1,015 reviews)

"Enjoyable place to stay. The museum adds a unique experience and atmosphere!"

Reviewed on Jul 10, 2026

Hyatt Regency Cincinnati

151 West Fifth Street Cincinnati OH

$152 nightly

$181 total

Jul 20 - Jul 21

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,674 reviews)

"Room was clean and comfortable. Staff upon checking in and checking out were friendly and helpful. Within walking distance of the ballpark and riverfront."

Reviewed on Jul 13, 2026

voco The Clair Cincinnati Downtown by IHG

701 Broadway Street Cincinnati OH

$142 nightly

$169 total

Jul 19 - Jul 20

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. Self parking, a coffee ...

9.2/10 Wonderful! (1,288 reviews)

"This is a really nice hotel. It’s clean and I like that you have to scan your key card to use the elevators. It lets you off on your floor. They also have a nice bar."

Reviewed on Jul 13, 2026

Graduate by Hilton Cincinnati

151 Goodman St Cincinnati OH

Fully refundableReserve now, pay when you stay

$139 nightly

$165 total

Jul 20 - Jul 21

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, conference center, ...

9.4/10 Exceptional! (1,367 reviews)

"Very cute and centrally located. Comfortable bed and rooms. Desk clerk very friendly."

Reviewed on Jul 11, 2026

Hotel Covington Cincinnati Riverfront

638 Madison Ave Covington KY

Fully refundableReserve now, pay when you stay

$249 nightly

$280 total

Jul 19 - Jul 20

Total with taxes and fees

This hotel features a restaurant and 2 bars/lounges. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and free airport ...

9.6/10 Exceptional! (1,018 reviews)

"Nice place to stay!!! Everything was great."

Reviewed on Jul 12, 2026

Renaissance Cincinnati Downtown Hotel

36 East Fourth Street Cincinnati OH

Fully refundableReserve now, pay when you stay

$209 nightly

$249 total

Jul 14 - Jul 15

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

8.8/10 Excellent! (1,016 reviews)

"Everyone was so helpful and nice. I wish I would have known about the Streetcar before my arrival, I would have planned for some additional activities during my stay. Otherwise, EXCELLENT stay!!"

Reviewed on Jul 13, 2026

Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel

310 STRAIGHT STREET CINCINNATI Cincinnati OH

Fully refundableReserve now, pay when you stay

$152 nightly

$181 total

Jul 23 - Jul 24

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

9.4/10 Exceptional! (302 reviews)

"The only negative feedback I have is that this hotel does not have a parking garage."

Reviewed on Jul 11, 2026

The Cincinnatian Hotel Curio Collection by Hilton

601 Vine Street Cincinnati OH

$147 nightly

$175 total

Jul 19 - Jul 20

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

7.8/10 Good! (1,012 reviews)

"We arrived early on Thursday and we were able to check in with the help of the front desk. I didn’t get her name but she was super helpful getting us into a room. Our room was spacious and comfortable and clean. We had breakfast at the coffee shop downstairs and our bagels were excellent. I will ..."

Reviewed on Jul 11, 2026

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4 Star Hotels Uptown

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Uptown 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Uptown will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Uptown, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Uptown hotel reviews by fellow wanderers

Hilton Cincinnati Netherland Plaza

4 out of 5

Posted less than an hour ago

Travelocity Verified Review

"Good location in downtown and attached to a large parking deck, so that's convenient. The public areas are OK. Overall the property is definitely showing a lot of wear and tear. Peeling paint along the baseboards in our room, some damage to the bathtub, worn carpet and general dinginess & age all around. Everything was clean enough and I don't think it should be avoided at all. But it's not really up to what I would expect for a 4-star Hilton property."

A verified traveler stayed at Hilton Cincinnati Netherland Plaza