Explore top 2025 4 Star Hotels in Uptown

Name: Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel
Price range: $179 total
Rating: 9.2

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Top Uptown 4 Star hotels

Hilton Cincinnati Netherland Plaza

35 W 5th St, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$135 nightly

$161 total

Oct 2 - Oct 3

Total with taxes and fees

This historic hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...

7.8/10 Good! (1,212 reviews)

"The hotel was lovely inside. Very nice restaurant called the 1931. The room was nice. The only issue was the pillows were worn."

Reviewed on Sep 24, 2025

Hyatt Regency Cincinnati

151 West Fifth Street, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$144 nightly

$172 total

Oct 19 - Oct 20

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

8.8/10 Excellent! (1,553 reviews)

A Jazza-lishes stay

"Very clean rooms! the staff in the restaurant were very friendly and cordial. The lobby itself is very retro and chic. The king bed my wife and I slept in was so comfortable! And our view we had on the 21st floor was Jaw dropping :) perfect for going to a football/baseball game and exploring local ..."

Reviewed on Sep 20, 2025

The Westin Cincinnati

21 E 5th St, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$135 nightly

$161 total

Sep 27 - Sep 28

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling for business? Take advantage of the business center, express check-out, and conference space. ...

8.4/10 Very Good! (1,075 reviews)

"great room overlooking park. free bus shuttle just around corner. fast elevators to our 9 th floor"

Reviewed on Sep 23, 2025

The Cincinnatian Hotel Curio Collection by Hilton

601 Vine Street, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$152 nightly

$182 total

Oct 9 - Oct 10

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

7.6/10 Good! (1,002 reviews)

"Our room was huge! 2 king beds, more like a suite. Convenient snacks downstairs and great breakfast/coffee place. Very pleasant staff. The walk to TQL was a bit longer than we expected though. Had to Uber."

Reviewed on Sep 25, 2025

21c Museum Hotel Cincinnati

609 Walnut St, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$184 nightly

$219 total

Oct 19 - Oct 20

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...

8.6/10 Excellent! (1,011 reviews)

"Art work"

Reviewed on Sep 21, 2025

Graduate by Hilton Cincinnati

151 Goodman St, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$135 nightly

$161 total

Oct 13 - Oct 14

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, conference center, ...

9.2/10 Wonderful! (1,328 reviews)

"The wallpaper in the bathroom"

Reviewed on Sep 15, 2025

Renaissance Cincinnati Downtown Hotel

36 East Fourth Street, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$189 nightly

$225 total

Sep 27 - Sep 28

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

8.6/10 Excellent! (1,031 reviews)

"Great staff, felt very welcomed upon arrival"

Reviewed on Sep 21, 2025

Hotel Covington Cincinnati Riverfront

638 Madison Ave, Covington, KY

$239 nightly

$269 total

Sep 28 - Sep 29

Total with taxes and fees

This hotel features a restaurant and 2 bars/lounges. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and free airport ...

9.4/10 Exceptional! (1,009 reviews)

"This place smells heavenly. Great art and staff was so friendly!"

Reviewed on Sep 21, 2025

The Summit Hotel

5345 Medpace Way, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$179 nightly

$214 total

Oct 12 - Oct 13

Total with taxes and fees

This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

9.2/10 Wonderful! (1,007 reviews)

"Good hotel"

Reviewed on Sep 20, 2025

Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel

310 STRAIGHT STREET CINCINNATI, Cincinnati, OH

Fully refundableReserve now, pay when you stay

$150 nightly

$179 total

Oct 19 - Oct 20

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. WiFi in public areas is free. Valet parking, a coffee shop, and a terrace are also offered.

9.2/10 Wonderful! (145 reviews)

"New hotel with a rooftop bar. Will definitely stay here again."

Reviewed on Sep 20, 2025

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4 Star Hotels Uptown

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Uptown 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Uptown will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Uptown, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Uptown hotel reviews by fellow wanderers

The Cincinnatian Hotel Curio Collection by Hilton

5 out of 5

Posted 2 days ago

Travelocity Verified Review

A verified traveler stayed at The Cincinnatian Hotel Curio Collection by Hilton

voco The Clair Cincinnati Downtown by IHG

5 out of 5

Posted 2 days ago

Travelocity Verified Review

"Absolutely Loved this Property Malia at the Front Desk was Amazing!!! She was so kind and helpful with anything we needed !! The parking was very easy across the street and was around $12.50 or so to park overnight . We walked to Great American Ballpark for a Reds game and there were plenty of dining options to choose from . We are Definitely planning on staying here again !!! Walked Down Sycamore to get to the ballpark !! They also have dining and bar onsite ."

A verified traveler stayed at voco The Clair Cincinnati Downtown by IHG