Explore top 2026 4 Star Hotels in Uptown

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May 29 - May 31
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Top Uptown 4 Star hotels

Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

4 out of 5
35 W 5th St Cincinnati OH
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $153 total per night from May 31 to Jun 1
$153 total
May 31 - Jun 1
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...
8/10 Very Good! (1,495 reviews)
"By far one of the coolest visuals of any hotel ive stayed in! The bar reminds me of the roaring 20s and looks like a spot Frank Sinatra would hang out in. Great drinks in particular the old fashion and the staff was great as well! Super comfy bed and walkable to so many other spots to dine or ..."

Reviewed on May 27, 2026

Opens in a new windowHilton Cincinnati Netherland Plaza
The Westin Cincinnati

The Westin Cincinnati

4 out of 5
21 E 5th St Cincinnati OH
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $181 total per night from May 28 to May 29
$181 total
May 28 - May 29
Total with taxes and fees
A restaurant and a bar/lounge are featured at this hotel. Traveling for business? Take advantage of the business center, express check-out, and conference space. ...
8.6/10 Excellent! (1,309 reviews)
"An early check in was accommodated and very friendly staff. Bed was very comfortable and room temp was nice"

Reviewed on May 26, 2026

Opens in a new windowThe Westin Cincinnati
Hyatt Regency Cincinnati

Hyatt Regency Cincinnati

4 out of 5
151 West Fifth Street Cincinnati OH
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $181 total per night from Jun 7 to Jun 8
$181 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
9/10 Wonderful! (1,644 reviews)
"The room was perfect and the view was beautiful. We could easily walk everywhere we wanted to go. We had a wonderful lunch in their restaurant. The marketplace had some good options when we got back from the ballpark after our game went into 11 innings Can’t say enough! We had a wonderful visit"

Reviewed on May 25, 2026

Opens in a new windowHyatt Regency Cincinnati
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

4.5 out of 5
609 Walnut St Cincinnati OH
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $219 total per night from May 31 to Jun 1
$219 total
May 31 - Jun 1
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...
8.6/10 Excellent! (1,005 reviews)
"Staff was all wonderful and extremely nice to me and my wife. Very helpful with information about how to get around the city easier. Breakfast at the restaurant was great as well. Hotel and room were both clean. The only complaint was the bed wasn’t very comfortable to us."

Reviewed on May 25, 2026

Opens in a new window21c Museum Hotel Cincinnati
voco The Clair Cincinnati Downtown by IHG

voco The Clair Cincinnati Downtown by IHG

4 out of 5
701 Broadway Street Cincinnati OH
Fully refundable
$140 nightly
The price is $167 total per night from May 31 to Jun 1
$167 total
May 31 - Jun 1
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. Self parking, a coffee ...
Opens in a new windowvoco The Clair Cincinnati Downtown by IHG
Hotel Covington Cincinnati Riverfront

Hotel Covington Cincinnati Riverfront

4 out of 5
638 Madison Ave Covington KY
Fully refundableReserve now, pay when you stay
$258 nightly
The price is $290 total per night from May 31 to Jun 1
$290 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant and 2 bars/lounges. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and free airport ...
9.6/10 Exceptional! (1,001 reviews)
"There was terrible smell from AC unit, and it didn’t feel clean as well. We wouldn’t book that again. Price doesn’t match with quality and the room."

Reviewed on May 27, 2026

Opens in a new windowHotel Covington Cincinnati Riverfront
Graduate by Hilton Cincinnati

Graduate by Hilton Cincinnati

4 out of 5
151 Goodman St Cincinnati OH
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $185 total per night from May 31 to Jun 1
$185 total
May 31 - Jun 1
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, conference center, ...
9.4/10 Exceptional! (1,350 reviews)
"Great hotel for a reasonable price"

Reviewed on May 25, 2026

Opens in a new windowGraduate by Hilton Cincinnati
Renaissance Cincinnati Downtown Hotel

Renaissance Cincinnati Downtown Hotel

4 out of 5
36 East Fourth Street Cincinnati OH
Fully refundableReserve now, pay when you stay
$189 nightly
The price is $225 total per night from May 28 to May 29
$225 total
May 28 - May 29
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...
8.8/10 Excellent! (1,009 reviews)
"Beautiful hotel and staff were very nice and friendly 5 stars all around!"

Reviewed on May 25, 2026

Opens in a new windowRenaissance Cincinnati Downtown Hotel
AC Hotel by Marriott Cincinnati at The Banks

AC Hotel by Marriott Cincinnati at The Banks

4 out of 5
135 Joe Nuxhall Way Cincinnati OH
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $237 total per night from May 31 to Jun 1
$237 total
May 31 - Jun 1
Total with taxes and fees
The hotel's gym, a rooftop terrace, and 2 bars/lounges are among the featured amenities. Traveling on business? Take advantage of the business center, free WiFi ...
9.2/10 Wonderful! (1,000 reviews)
"Love staying here. Nice room. Nice bed. Great breakfast. The best part is overwhelmingly the staff! Everyone is always friendly and helpful. Will always stay here when we come to Cincinnati."

Reviewed on May 26, 2026

Opens in a new windowAC Hotel by Marriott Cincinnati at The Banks
DoubleTree by Hilton Cincinnati Airport

DoubleTree by Hilton Cincinnati Airport

4 out of 5
2826 Terminal Drive Florence KY
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $142 total per night from Jun 7 to Jun 8
$142 total
Jun 7 - Jun 8
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
8.4/10 Very Good! (1,000 reviews)
"Clean and easy stay."

Reviewed on May 25, 2026

Opens in a new windowDoubleTree by Hilton Cincinnati Airport
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4 Star Hotels Uptown

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Uptown 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Uptown will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Uptown, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Uptown hotel reviews by fellow wanderers

Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

5 out of 5
Posted 2 hours ago
Travelocity Verified Review
"By far one of the coolest visuals of any hotel ive stayed in! The bar reminds me of the roaring 20s and looks like a spot Frank Sinatra would hang out in. Great drinks in particular the old fashion and the staff was great as well! Super comfy bed and walkable to so many other spots to dine or drink."
A verified traveler stayed at Hilton Cincinnati Netherland Plaza
Hilton Cincinnati Netherland Plaza

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