Explore top 2026 4 Star Hotels in Panama City

Name: Courtyard by Marriott Panama Multiplaza Mall
Price range: $130 total
Rating: 9

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Top Panama City 4 Star hotels

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

Fully refundable

$140 nightly

$154 total

Nov 10 - Nov 11

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...

8.6/10 Excellent! (2,753 reviews)

"Walls were very thin and the fire at the restaurant was so so on portion size and flavor profile. Transportation only runs every hour"

Reviewed on Oct 9, 2026

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama

Fully refundableReserve now, pay when you stay

$183 nightly

$202 total

Nov 8 - Nov 9

Total with taxes and fees

A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in ...

Megapolis Hotel Panamá

Avenida Balboa Panama City

Fully refundableReserve now, pay when you stay

$136 nightly

$149 total

Oct 31 - Nov 1

Total with taxes and fees

This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...

8.6/10 Excellent! (1,776 reviews)

"Breakfast"

Reviewed on Oct 10, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama

Fully refundableReserve now, pay when you stay

$111 nightly

$122 total

Nov 9 - Nov 10

Total with taxes and fees

This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...

7.8/10 Good! (1,001 reviews)

"We just didn’t have a microwave. Staff was amazing, breakfast variety was good everyday. Will be back!"

Reviewed on Oct 9, 2026

Ramada Plaza by Wyndham Panama Punta Pacifica

Via Israel y Calle 71, San Francisco Panama City Panama

$105 nightly

$115 total

Nov 9 - Nov 10

Total with taxes and fees

This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

Dreams Playa Bonita Panama - All Inclusive

KM 7, Road to Veracruz Veracruz Panama

Fully refundableReserve now, pay when you stay

$278 nightly

$278 total

Oct 11 - Oct 12

Total with taxes and fees

A full-service spa is on site and multilingual staff is available around-the-clock at the 24-hour front desk. Spend a day at the beach kayaking, or relax with ...

7.8/10 Good! (1,105 reviews)

"."

Reviewed on Oct 9, 2026

Riande Aeropuerto Hotel & Casino

Vía Tocumen Tocumen Panama

Fully refundableReserve now, pay when you stay

$108 nightly

$119 total

Nov 9 - Nov 10

Total with taxes and fees

This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly ...

Decapolis Hotel Panama City

Avenida Balboa Con Multicentro Panama City Panama

Fully refundableReserve now, pay when you stay

$87 nightly

$96 total

Oct 31 - Nov 1

Total with taxes and fees

This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express ...

Courtyard by Marriott Panama Metromall

Avenida Domingo Diaz via Tocumen San Miguelito Panama

Fully refundableReserve now, pay when you stay

$101 nightly

$111 total

Oct 30 - Oct 31

Total with taxes and fees

This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...

Courtyard by Marriott Panama Multiplaza Mall

Via Israel Multiplaza Pacific Mall Panama City Panama

$118 nightly

$130 total

Oct 31 - Nov 1

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...

9/10 Wonderful! (1,008 reviews)

"Nice Place to Stay in Panama"

Reviewed on Oct 9, 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Panama City

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Panama City 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Panama City will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Panama City, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.