Explore top 2026 4 Star Hotels in Uptown

Name: The Cincinnatian Hotel Curio Collection by Hilton
Price range: $179 total
Rating: 7.8

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Top Uptown 4 Star hotels

Hilton Cincinnati Netherland Plaza

35 W 5th St Cincinnati OH

$127 nightly

$151 total

Jul 20 - Jul 21

Total with taxes and fees

This smoke-free hotel features 2 restaurants, a bar/lounge, and A 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in public ...

8/10 Very Good! (1,625 reviews)

"A grand old hotel, for sure, with superb elegant 30s architecture and decorations. However, the staff was certainly an elegant, and rather rude. The places falling apart, with peeling. paint on the trim, Old worn out carpets, and torn leather seats in the dining room. Finally, the bathroom had a ..."

Reviewed on Jul 13, 2026

The Westin Cincinnati

21 E 5th St Cincinnati OH

$152 nightly

$181 total

Aug 6 - Aug 7

Total with taxes and fees

A restaurant and a bar/lounge are featured at this hotel. Traveling for business? Take advantage of the business center, express check-out, and conference space. ...

8.6/10 Excellent! (1,405 reviews)

"room was as advertised, no working ice machines, breakfast area was disappointing, the display for the menu was not working and the staff did not acknowledge us while we were standing there waiting to be helped"

Reviewed on Jul 13, 2026

21c Museum Hotel Cincinnati

609 Walnut St Cincinnati OH

$165 nightly

$197 total

Aug 3 - Aug 4

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Relax with a drink at the bar/lounge and enjoy perks like free ...

8.6/10 Excellent! (1,015 reviews)

"Enjoyable place to stay. The museum adds a unique experience and atmosphere!"

Reviewed on Jul 10, 2026

Hyatt Regency Cincinnati

151 West Fifth Street Cincinnati OH

$152 nightly

$181 total

Jul 20 - Jul 21

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...

9/10 Wonderful! (1,676 reviews)

"Room was clean and comfortable. Staff upon checking in and checking out were friendly and helpful. Within walking distance of the ballpark and riverfront."

Reviewed on Jul 13, 2026

voco The Clair Cincinnati Downtown by IHG

701 Broadway Street Cincinnati OH

$142 nightly

$169 total

Jul 19 - Jul 20

Total with taxes and fees

This hotel features an indoor pool, a 24-hour gym, and a restaurant. Relax with a drink at the bar/lounge and enjoy perks like free WiFi. Self parking, a coffee ...

9.2/10 Wonderful! (1,289 reviews)

"The hotel is clean and the room was nice and very clean, plus comfortable beds. Pool was good, fitness has very little equipment, some did not work."

Reviewed on Jul 13, 2026

Graduate by Hilton Cincinnati

151 Goodman St Cincinnati OH

Fully refundableReserve now, pay when you stay

$139 nightly

$165 total

Jul 20 - Jul 21

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, conference center, ...

9.4/10 Exceptional! (1,368 reviews)

"Very cute and centrally located. Comfortable bed and rooms. Desk clerk very friendly."

Reviewed on Jul 11, 2026

Hotel Covington Cincinnati Riverfront

638 Madison Ave Covington KY

Fully refundableReserve now, pay when you stay

$220 nightly

$247 total

Jul 16 - Jul 17

Total with taxes and fees

This hotel features a restaurant and 2 bars/lounges. Traveling on business? Take advantage of the free WiFi in public areas, express check-in, and free airport ...

9.6/10 Exceptional! (1,019 reviews)

"Loved our stay at the Hotel Covington North! The room was gorgeous! The artistic light installation in the atrium outside our windows was special. Wish I had booked a longer stay."

Reviewed on Jul 14, 2026

Renaissance Cincinnati Downtown Hotel

36 East Fourth Street Cincinnati OH

$209 nightly

$249 total

Jul 15 - Jul 16

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and ...

8.8/10 Excellent! (1,017 reviews)

"The room had smell , like cigarette smoke. The bathroom door would not close. The staff was very nice, the valet and consige where excellent. The staff was great"

Reviewed on Jul 13, 2026

Hotel Celare, Cincinnati Midtown, a Tribute Portfolio Hotel

310 STRAIGHT STREET CINCINNATI Cincinnati OH

$152 nightly

$181 total

Jul 20 - Jul 21

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

9.4/10 Exceptional! (303 reviews)

"Great hotel and location, staff was excellent!"

Reviewed on Jul 13, 2026

The Cincinnatian Hotel Curio Collection by Hilton

601 Vine Street Cincinnati OH

$150 nightly

$179 total

Aug 9 - Aug 10

Total with taxes and fees

This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet ...

7.8/10 Good! (1,012 reviews)

"We arrived early on Thursday and we were able to check in with the help of the front desk. I didn’t get her name but she was super helpful getting us into a room. Our room was spacious and comfortable and clean. We had breakfast at the coffee shop downstairs and our bagels were excellent. I will ..."

Reviewed on Jul 11, 2026

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4 Star Hotels Uptown

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Uptown 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Uptown will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Uptown, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.