Explore top 2025 4 Star Hotels in South Indianapolis

Name: Hyatt Regency Indianapolis
Price range: $193 total
Rating: 8.8

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Top South Indianapolis 4 Star hotels

Ironworks Hotel Indy

2721 E 86th Street, Indianapolis, IN

Fully refundableReserve now, pay when you stay

$199 nightly

$233 total

Sep 28 - Sep 29

Total with taxes and fees

This smoke-free hotel's 4 restaurants, 3 bars/lounges, and 24-hour gym are some of the featured amenities. Traveling on business? Take advantage of the business ...

9.6/10 Exceptional! (1,622 reviews)

"Everything was great! When we come to Indy, this is where we like to stay!!!! We would definitely recommend to others!"

Reviewed on Sep 21, 2025

JW Marriott Indianapolis

10 S West Street, Indianapolis, IN

$195 nightly

$229 total

Oct 24 - Oct 25

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (1,292 reviews)

"We had a great time! The hotel was extremely comfortable with plenty to do in the area!"

Reviewed on Sep 24, 2025

Sheraton Indianapolis Hotel at Keystone Crossing

8787 Keystone Crossing, Indianapolis, IN

Fully refundableReserve now, pay when you stay

$87 nightly

$102 total

Oct 5 - Oct 6

Total with taxes and fees

This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...

8.6/10 Excellent! (1,342 reviews)

"Wonderful restaurant breakfast. Superb staff. Amazing room"

Reviewed on Sep 21, 2025

Bottleworks Hotel

850 Massachusetts Avenue, Indianapolis, IN

$199 nightly

$234 total

Sep 28 - Sep 29

Total with taxes and fees

A full-service spa, a gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the steam room and perks like free WiFi. A bar/lounge, a 24-hour ...

9.8/10 Exceptional! (1,582 reviews)

"Amazing property! Great, friendly staff! Love the valet team!!!! Front deck was extremely helpful! Rooms!! What can I say…the rooms are awesome!!"

Reviewed on Sep 23, 2025

Omni Severin Hotel

40 West Jackson Place, Indianapolis, IN

Fully refundableReserve now, pay when you stay

$184 nightly

$216 total

Oct 9 - Oct 10

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

9.2/10 Wonderful! (626 reviews)

"Great location Downtown. Felt safe. Hotel was clean and staff were very friendly. Valet was expensive but location wise to be expected."

Reviewed on Sep 24, 2025

Marriott Indianapolis Downtown

350 W Maryland St, Indianapolis, IN

Fully refundableReserve now, pay when you stay

$187 nightly

$220 total

Sep 30 - Oct 1

Total with taxes and fees

This hotel features 2 coffee shops/cafes and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. ...

8.8/10 Excellent! (1,012 reviews)

"Great gym, great staff. Really enjoyed my 2 days and 1 night there."

Reviewed on Sep 25, 2025

Marriott Indianapolis North

3645 River Crossing Pkwy, Indianapolis, IN

Fully refundableReserve now, pay when you stay

$199 nightly

$233 total

Sep 27 - Sep 28

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...

8.8/10 Excellent! (1,001 reviews)

"Loved the view of the lake from my room."

Reviewed on Sep 22, 2025

The Alexander

333 S Delaware St, Indianapolis, IN

$152 nightly

$179 total

Sep 30 - Oct 1

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the free WiFi in public areas, laundry service, and ...

8.8/10 Excellent! (1,006 reviews)

"The accommodation the friendliness of the staff and the food was great!"

Reviewed on Sep 16, 2025

Sheraton Indianapolis City Centre Hotel

31 W Ohio St, Indianapolis, IN

Fully refundableReserve now, pay when you stay

$143 nightly

$168 total

Oct 18 - Oct 19

Total with taxes and fees

This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...

8.4/10 Very Good! (1,004 reviews)

"Very sleek and clean feeling. Rooms were nice and very little noise heard from the room. Heard the people above us doing aerobics, but probably the least loud I’ve ever heard it in a hotel lol"

Reviewed on Sep 21, 2025

Hyatt Regency Indianapolis

One South Capitol Avenue, Indianapolis, IN

Fully refundableReserve now, pay when you stay

$164 nightly

$193 total

Oct 17 - Oct 18

Total with taxes and fees

This smoke-free hotel includes 3 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...

8.8/10 Excellent! (1,021 reviews)

"Great stay. Convenient location."

Reviewed on Sep 24, 2025

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4 Star Hotels South Indianapolis

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in South Indianapolis 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in South Indianapolis will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in South Indianapolis, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.