Explore top 2026 4 Star Hotels in Panama City

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Top Panama City 4 Star hotels

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Dec 7 to Dec 8
$121 total
Dec 7 - Dec 8
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
7.8/10 Good! (1,018 reviews)
"Muy mala la atención, no fueron amables, no accedieron a mi petición de una habitación en 1 piso por estar con niños pequeños, mala distribución de toallas, papel, etc"

Reviewed on Nov 10, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$145 nightly
The price is $160 total per night from Dec 8 to Dec 9
$160 total
Dec 8 - Dec 9
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
8.6/10 Excellent! (2,795 reviews)
"For our short stay in a new country, staff made us feel welcomed to Panama"

Reviewed on Nov 10, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $166 total per night from Nov 11 to Nov 12
$166 total
Nov 11 - Nov 12
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public ...
8.6/10 Excellent! (1,862 reviews)
"I stayed for 4 days with a group of cousins and we had a great time at the hotel, pool view was nice, stadium bar room with pool tables was a plus for us we really enjoyed, the service overall was great, really happy with the stay !"

Reviewed on Nov 10, 2026

Opens in a new windowMegapolis Hotel Panamá
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

4 out of 5
Via Israel y Calle 71, San Francisco Panama City Panama
$115 nightly
The price is $126 total per night from Nov 16 to Nov 17
$126 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
9.6/10 Exceptional! (1,428 reviews)
"Buffet breakfast was pretty good. Hotel is in a good location for restaurants and bars as well. Staff were generally friendly and welcoming. My main concern is that I was not offered a room upgrade as per my VIP status perk l, and when I asked about it as well as a late checkout, the front desk person ..."

Reviewed on Nov 8, 2026

Opens in a new windowRamada Plaza by Wyndham Panama Punta Pacifica
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $185 total per night from Nov 15 to Nov 16
$185 total
Nov 15 - Nov 16
Total with taxes and fees
A full-service spa, 3 restaurants, and an outdoor pool are all featured at this Belle Époque hotel. Traveling on business? Take advantage of the free WiFi in ...
9.2/10 Wonderful! (1,009 reviews)
"Great location."

Reviewed on Nov 9, 2026

Opens in a new windowCentral Hotel Panama Casco Viejo
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Vía Tocumen Tocumen Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Nov 15 to Nov 16
$119 total
Nov 15 - Nov 16
Total with taxes and fees
This smoke-free resort features a casino, 2 indoor tennis courts, and a restaurant. Bring the family and enjoy the children's pool, playground, and kid-friendly ...
8.6/10 Excellent! (1,819 reviews)
"The best hotel when you need to stay near the airport in Panama. I booked this hotel for my mom, she had to stay overnight in Panama, before her next flight. Hotel offers shuttle services and the staff are always very helpful."

Reviewed on Nov 9, 2026

Opens in a new windowRiande Aeropuerto Hotel & Casino
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$263 nightly
The price is $263 total per night from Dec 1 to Dec 2
$263 total
Dec 1 - Dec 2
Total with taxes and fees
A full-service spa is on site and multilingual staff is available around-the-clock at the 24-hour front desk. Spend a day at the beach kayaking, or relax with ...
7.8/10 Good! (1,129 reviews)
"The resort was nice overall for what it offers. There is definitely room for improvement, especially when it comes to updating the locks and adding a fresh coat of paint. It’s a peaceful and relaxing place, and the staff were absolutely wonderful, welcoming, and attentive. The location was pretty ..."

Reviewed on Nov 9, 2026

Opens in a new windowDreams Playa Bonita Panama - All Inclusive
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $144 total per night from Nov 28 to Nov 29
$144 total
Nov 28 - Nov 29
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
9/10 Wonderful! (1,006 reviews)
"Muy bueno, limpio y cómodo. El restaurante del desayuno si es un poco"

Reviewed on Nov 9, 2026

Opens in a new windowCourtyard by Marriott Panama Multiplaza Mall
Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
Avenida Balboa Con Multicentro Panama City Panama
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $121 total per night from Dec 11 to Dec 12
$121 total
Dec 11 - Dec 12
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express ...
Opens in a new windowDecapolis Hotel Panama City
Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District

4.5 out of 5
C. Aquilino de la Guardia Panama City Panamá Province
Fully refundableReserve now, pay when you stay
$106 nightly
The price is $119 total per night from Dec 11 to Dec 12
$119 total
Dec 11 - Dec 12
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public ...
Opens in a new windowHotel Dann Carlton Marinn Place Panama Financial District
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4 Star Hotels Panama City

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Panama City 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Panama City will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Panama City, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Panama City hotel reviews by fellow wanderers

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