Explore top 2026 4 Star Hotels in O'Fallon

Seize Your Someday with our amazing deals for the whole family!

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Top O'Fallon 4 Star hotels

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Jun 28 to Jun 29
$158 total
Jun 28 - Jun 29
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,100 reviews)
"The room was very clean the bars was beautiful enjoyed our stay!"

Reviewed on Jun 7, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $226 total per night from Jul 1 to Jul 2
$226 total
Jul 1 - Jul 2
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside ...
8.6/10 Excellent! (1,007 reviews)
"Room was large with separate sitting area. Shower was fantastic"

Reviewed on Jun 5, 2026

Opens in a new windowAmeristar Casino Resort and Spa
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
Fully refundableReserve now, pay when you stay
$156 nightly
The price is $187 total per night from Jul 3 to Jul 4
$187 total
Jul 3 - Jul 4
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-in, and free airport ...
8/10 Very Good! (1,002 reviews)
"So convenient to the airport and shuttle 14/7. Buffett breakfast was fabulous. Would stay again"

Reviewed on May 25, 2026

Opens in a new windowMarriott St. Louis Airport
DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport

4 out of 5
4505 Woodson Road St. Louis MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $119 total per night from Jul 5 to Jul 6
$119 total
Jul 5 - Jul 6
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Bring the family and enjoy the arcade/game room and kid-friendly dining. There's no skimping ...
7.8/10 Good! (967 reviews)
"Server was gone for a long time and wanted to close early."

Reviewed on Jun 8, 2026

Opens in a new windowDoubleTree by Hilton St. Louis Airport
DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport

4 out of 5
1973 Craigshire Rd Maryland Heights MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $145 total per night from Jun 14 to Jun 15
$145 total
Jun 14 - Jun 15
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (1,001 reviews)
"The restaurant has an amazing salad and the bartender (I forgot his name) is excellent. If I’m ever in St. Louis again I’ll definitely stay there"

Reviewed on May 29, 2026

Opens in a new windowDoubleTree by Hilton St. Louis - Westport
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4 out of 5
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $155 total per night from Jul 8 to Jul 9
$155 total
Jul 8 - Jul 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (1,003 reviews)
"everything was fine except we were assigned a room in an outbuilding without an elevator and not attached to the building that housed the restaurants and lobby."

Reviewed on Jun 8, 2026

Opens in a new windowHilton St. Louis Frontenac
DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4 out of 5
16625 Swingley Ridge Rd Chesterfield MO
$144 nightly
The price is $167 total per night from Jul 5 to Jul 6
$167 total
Jul 5 - Jul 6
Total with taxes and fees
7 indoor tennis courts, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
8.8/10 Excellent! (1,002 reviews)
"Stayed at this hotel for the weekend. Very nice hotel. Check in was easy. Stayed in king size bed room, with couch sofa. It was nice, didn’t use the sofa, but the room size was good for 2 ppl. Maybe it would be alittle crowded with more. Their beds are really comfortable. And showers have great pressure. ..."

Reviewed on May 23, 2026

Opens in a new windowDoubleTree by Hilton Hotel St. Louis - Chesterfield
The Inn at Elijah McLeans

The Inn at Elijah McLeans

4 out of 5
602 W Front St Washington MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $164 total per night from Jun 9 to Jun 10
$164 total
Jun 9 - Jun 10
Total with taxes and fees
This guesthouse doesn't skimp on freebies - guests receive free WiFi and free self parking. A bar/lounge is also provided.
9/10 Wonderful! (145 reviews)
"Self-check-in was efficient and easy! Staff was very friendly. We ate a delicious meal at the restaurant onsite. Service at the restaurant was exceptional. The room was spacious, clean and the bed was comfortable."

Reviewed on Jun 6, 2026

Opens in a new windowThe Inn at Elijah McLeans
Landing Apartments - Eureka

Landing Apartments - Eureka

4 out of 5
400 Legends Terrace Dr Eureka MO
This aparthotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. Barbecue ...
Opens in a new windowLanding Apartments - Eureka
'the Ruebling House': Bright, Modern, & Renovated!

'the Ruebling House': Bright, Modern, & Renovated!

4 out of 5
Defiance MO
Free WiFi in public areas is available at this apartment. Take advantage of the free self parking.
Opens in a new window'the Ruebling House': Bright, Modern, & Renovated!
Don't see what you're looking for?
See all available properties in O'Fallon
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels O'Fallon

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in O'Fallon 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in O'Fallon will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in O'Fallon, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent O'Fallon hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity