Explore top 2026 4 Star Hotels in O'Fallon

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Top O'Fallon 4 Star hotels

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from May 8 to May 9
$143 total
May 8 - May 9
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,076 reviews)
Convenient for the airport

Reviewed on Apr 14, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $226 total per night from Apr 26 to Apr 27
$226 total
Apr 26 - Apr 27
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and outdoor pool, and unwind with a drink at the poolside ...
8.4/10 Very Good! (1,001 reviews)
Staff was super rude as a frequent traveler we abide by all rules and signs posted when there is no rules or signs posted you treat your guest like trash for not knowing the rules that you never explained in any way.. worst vacation EVER . STAY ANYWHERE ELSE BUT HERE!

Reviewed on Apr 11, 2026

Opens in a new windowAmeristar Casino Resort and Spa
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4 out of 5
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $171 total per night from May 3 to May 4
$171 total
May 3 - May 4
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.8/10 Excellent! (1,004 reviews)
Very short Staffed for Breakfast and almost out of all items. What they did have was very good.

Reviewed on Apr 17, 2026

Opens in a new windowHilton St. Louis Frontenac
DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport

4 out of 5
4505 Woodson Road St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from May 8 to May 9
$143 total
May 8 - May 9
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Bring the family and enjoy the arcade/game room and kid-friendly dining. There's no skimping ...
7.8/10 Good! (926 reviews)
Front desk was very friendly

Reviewed on Apr 13, 2026

Opens in a new windowDoubleTree by Hilton St. Louis Airport
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $173 total per night from May 8 to May 9
$173 total
May 8 - May 9
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-in, and free airport ...
Opens in a new windowMarriott St. Louis Airport
DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport

4 out of 5
1973 Craigshire Rd Maryland Heights MO
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $155 total per night from May 10 to May 11
$155 total
May 10 - May 11
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.2/10 Very Good! (1,000 reviews)
Room was clean eleavators broke breakfast was ok took forever to get creamer for coffee by front desk

Reviewed on Apr 14, 2026

Opens in a new windowDoubleTree by Hilton St. Louis - Westport
DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4 out of 5
16625 Swingley Ridge Rd Chesterfield MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $167 total per night from May 10 to May 11
$167 total
May 10 - May 11
Total with taxes and fees
7 indoor tennis courts, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
8.6/10 Excellent! (1,001 reviews)
Clean room, friendly & helpful staff, cook prepared omelette breakfast was yumyum. Really enjoyed our stay!

Reviewed on Apr 4, 2026

Opens in a new windowDoubleTree by Hilton Hotel St. Louis - Chesterfield
The Inn at Elijah McLeans

The Inn at Elijah McLeans

4 out of 5
602 W Front St Washington MO
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $164 total per night from Apr 27 to Apr 28
$164 total
Apr 27 - Apr 28
Total with taxes and fees
This inn doesn't skimp on freebies - guests receive free WiFi and free self parking. A bar/lounge is also provided.
9/10 Wonderful! (138 reviews)
All good, easy to find and great parking

Reviewed on Apr 15, 2026

Opens in a new windowThe Inn at Elijah McLeans
Landing Apartments - Eureka

Landing Apartments - Eureka

4 out of 5
400 Legends Terrace Dr Eureka MO
This aparthotel features a 24-hour gym and a seasonal outdoor pool. Guests will appreciate free perks like free self parking and WiFi in public areas. Barbecue ...
Opens in a new windowLanding Apartments - Eureka
'the Ruebling House': Bright, Modern, & Renovated!

'the Ruebling House': Bright, Modern, & Renovated!

4 out of 5
Defiance MO
Free WiFi in public areas is available at this apartment. Take advantage of the free self parking.
Opens in a new window'the Ruebling House': Bright, Modern, & Renovated!
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4 Star Hotels O'Fallon

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in O'Fallon 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in O'Fallon will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in O'Fallon, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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