Explore top 2026 4 Star Hotels in O'Fallon

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Top O'Fallon 4 Star hotels

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4 out of 5
1335 S Lindbergh Blvd Frontenac MO
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $152 total per night from Mar 1 to Mar 2
$152 total
Mar 1 - Mar 2
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8.6/10 Excellent! (1,001 reviews)
The room was very nice and clean. The staff made sure I had accommodations the check in and out was smooth.

Reviewed on Feb 7, 2026

Opens in a new windowHilton St. Louis Frontenac
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4 out of 5
9801 Natural Bridge Road St. Louis MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $143 total per night from Feb 21 to Feb 22
$143 total
Feb 21 - Feb 22
Total with taxes and fees
This hotel features an indoor pool, a 24-hour gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, laundry service, and ...
8.4/10 Very Good! (1,070 reviews)
Everything was excellent.

Reviewed on Feb 3, 2026

Opens in a new windowRenaissance St. Louis Airport Hotel
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $215 total per night from Mar 9 to Mar 10
$215 total
Mar 9 - Mar 10
Total with taxes and fees
This luxury hotel features a casino, a full-service spa, and 6 restaurants. Enjoy the 2 hot tubs and 24-hour gym, and unwind with a drink at the poolside ...
8.4/10 Very Good! (1,003 reviews)
The room was spotless and the employees went above and beyond for my fiancée and I. It was a wonderful stay and we look forward to staying again in the future. There is lots of food to choose from at Ameristar. Not to mention there is lots of fun to be had. We personally played the slots, ate dinner ...

Reviewed on Feb 6, 2026

Opens in a new windowAmeristar Casino Resort and Spa
Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
10700 Pear Tree Lane St. Louis MO
Fully refundableReserve now, pay when you stay
$145 nightly
The price is $173 total per night from Feb 20 to Feb 21
$173 total
Feb 20 - Feb 21
Total with taxes and fees
This hotel features an indoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the business center, express check-in, and free airport ...
7.8/10 Good! (1,001 reviews)
The staff was great and the hotel was beautiful for location. It looked well maintained.

Reviewed on Jan 11, 2026

Opens in a new windowMarriott St. Louis Airport
DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport

4 out of 5
1973 Craigshire Rd Maryland Heights MO
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $145 total per night from Feb 22 to Feb 23
$145 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
8/10 Very Good! (1,000 reviews)
Love this hotel

Reviewed on Jan 4, 2026

Opens in a new windowDoubleTree by Hilton St. Louis - Westport
DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport

4 out of 5
4505 Woodson Road St. Louis MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $113 total per night from Feb 22 to Feb 23
$113 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Bring the family and enjoy the arcade/game room and kid-friendly dining. There's no skimping ...
7.8/10 Good! (887 reviews)
Nice spot

Reviewed on Feb 2, 2026

Opens in a new windowDoubleTree by Hilton St. Louis Airport
DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield

4 out of 5
16625 Swingley Ridge Rd Chesterfield MO
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $143 total per night from Feb 16 to Feb 17
$143 total
Feb 16 - Feb 17
Total with taxes and fees
7 indoor tennis courts, an indoor pool, and a gym are all featured at this smoke-free hotel. Traveling on business? Take advantage of the 24-hour business center ...
8.6/10 Excellent! (1,000 reviews)
All the above

Reviewed on Dec 21, 2025

Opens in a new windowDoubleTree by Hilton Hotel St. Louis - Chesterfield
The Inn at Elijah McLeans

The Inn at Elijah McLeans

4 out of 5
602 W Front St Washington MO
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $154 total per night from Feb 15 to Feb 16
$154 total
Feb 15 - Feb 16
Total with taxes and fees
This inn doesn't skimp on freebies - guests receive free WiFi and free self parking. A bar/lounge is also provided.
8.8/10 Excellent! (134 reviews)
nice location, clean room, nice dinner option next door

Reviewed on Nov 2, 2025

Opens in a new windowThe Inn at Elijah McLeans
Historic Main Street Heritage Retreat

Historic Main Street Heritage Retreat

4 out of 5
Saint Charles MO
This apartment features laundry facilities.
9.4/10 Exceptional! (40 reviews)
Welcome email was informative.

Reviewed on Dec 22, 2025

Opens in a new windowHistoric Main Street Heritage Retreat
Convenient Apt W/shopping, Dining & Freeways

Convenient Apt W/shopping, Dining & Freeways

4 out of 5
Kingsbridge Lane 8650 St. Louis MO
This apartment doesn't skimp on freebies - guests receive free WiFi and free self parking. An outdoor pool and a virtual front desk are also provided.
Opens in a new windowConvenient Apt W/shopping, Dining & Freeways
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4 Star Hotels O'Fallon

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in O'Fallon 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in O'Fallon will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in O'Fallon, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

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