Explore 35 Luxury Hotels in Key West Historic District

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Best Luxury Hotels in Key West Historic District

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street, Key West, FL
$329 nightly
The price is $370 total per night from Oct 7 to Oct 8
$370 total
Oct 7 - Oct 8
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (568 reviews)
"Nearby and walking distance"

Reviewed on Sep 28, 2025

Opens in a new windowH2O Suites - Adults Only
The Gardens Hotel

The Gardens Hotel

526 Angela Street, Key West, FL
$224 nightly
The price is $252 total per night from Oct 28 to Oct 29
$252 total
Oct 28 - Oct 29
Total with taxes and fees
2 outdoor pools, 2 bars/lounges, and a restaurant are among this bed & breakfast's featured amenities. Business travelers can take advantage of the free WiFi ...
9.6/10 Exceptional! (1,003 reviews)
"Parking is somewhat limited and tight. Beautiful hotel, wonderful staff, well located."

Reviewed on Oct 3, 2025

Opens in a new windowThe Gardens Hotel
The Marquesa Hotel

The Marquesa Hotel

600 Fleming Street, Key West, FL
$193 nightly
The price is $217 total per night from Oct 26 to Oct 27
$217 total
Oct 26 - Oct 27
Total with taxes and fees
This eco-certified hotel features 3 outdoor pools, a restaurant, and a bar/lounge. Business travelers can take advantage of the laundry service. Self parking, ...
9.6/10 Exceptional! (1,002 reviews)
"The hotel was perfect!"

Reviewed on Oct 4, 2025

Opens in a new windowThe Marquesa Hotel
Duval House

Duval House

815 Duval St, Key West, FL
$121 nightly
The price is $133 total per night from Oct 7 to Oct 8
$133 total
Oct 7 - Oct 8
Total with taxes and fees
This bed & breakfast features a terrace, concierge services, and self parking. A garden, a picnic area, and express check-in are also on offer.
9.4/10 Exceptional! (1,001 reviews)
"The place has a great vibe and love the area. Great service and amenities. This was my 2nd stay and plan to stay again on my next trip to Key West."

Reviewed on Oct 3, 2025

Opens in a new windowDuval House
Silver Palms Inn

Silver Palms Inn

830 Truman Ave, Key West, FL
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $174 total per night from Oct 9 to Oct 10
$174 total
Oct 9 - Oct 10
Total with taxes and fees
An outdoor pool is featured at this hotel, along with free WiFi in public areas and luggage storage. Enjoy the free continental breakfast each morning. There's ...
9.2/10 Wonderful! (1,000 reviews)
"The balcony with two chairs slightly behind a palm tree, but facing the street was a really nice place to sit out in the morning while having breakfast."

Reviewed on Oct 2, 2025

Opens in a new windowSilver Palms Inn
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street, Key West, FL
Fully refundableReserve now, pay when you stay
$233 nightly
The price is $262 total per night from Oct 7 to Oct 8
$262 total
Oct 7 - Oct 8
Total with taxes and fees
This eco-certified hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi ...
9/10 Wonderful! (1,003 reviews)
"We had a nice stay at this hotel"

Reviewed on Oct 5, 2025

Opens in a new windowThe Marker Key West Harbor Resort
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

430 Duval St, Key West, FL
Fully refundableReserve now, pay when you stay
$219 nightly
The price is $246 total per night from Oct 7 to Oct 8
$246 total
Oct 7 - Oct 8
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...
8.8/10 Excellent! (219 reviews)
"Perfect place to stay in key west"

Reviewed on Oct 4, 2025

Opens in a new windowLa Concha Key West, Autograph Collection
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

413 Applerouth Lane, Key West, FL
$124 nightly
The price is $140 total per night from Oct 7 to Oct 8
$140 total
Oct 7 - Oct 8
Total with taxes and fees
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
8.8/10 Excellent! (1,002 reviews)
"Check in was easy. Facilities were well maintained, and most important centrally located so very walkable to everything we wanted to do."

Reviewed on Oct 4, 2025

Opens in a new windowThe Cabana Inn Key West - Adults Only
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More 4 star hotels in Key West Historic District

Key West Historic District Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West Historic District luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West Historic District to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West Historic District will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West Historic District, and plan your next opulent escape.


Key West Historic District hotels essential information

Accommodation
1,731 hotels
Lowest Price
$133
Highest Price
$370
Popular hotels
The Marker Key West Harbor Resort, H2O Suites - Adults Only, La Concha Key West, Autograph Collection, Silver Palms Inn, Duval House, The Cabana Inn Key West - Adults Only, The Gardens Hotel, The Marquesa Hotel

Popular Luxury Stays in Key West Historic District

Recent Key West Historic District Hotel Reviews By Fellow Wanderers

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