Explore 35 Luxury Hotels in Key West Historic District

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Best Luxury Hotels in Key West Historic District

H2O Suites - Adults Only

H2O Suites - Adults Only

1212 Simonton Street Key West FL
$367 nightly
The price is $413 total per night from Dec 2 to Dec 3
$413 total
Dec 2 - Dec 3
Total with taxes and fees
This hotel features a bar/lounge, a poolside bar, and an outdoor pool. Business travelers can take advantage of the laundry service. There's a gym on site, and ...
9.8/10 Exceptional! (577 reviews)
Everything is amazing about this place.

Reviewed on Nov 15, 2025

Opens in a new windowH2O Suites - Adults Only
The Gardens Hotel

The Gardens Hotel

526 Angela Street Key West FL
$274 nightly
The price is $308 total per night from Dec 2 to Dec 3
$308 total
Dec 2 - Dec 3
Total with taxes and fees
2 outdoor pools, 2 bars/lounges, and a restaurant are among this bed & breakfast's featured amenities. Business travelers can take advantage of the free WiFi ...
9.6/10 Exceptional! (1,000 reviews)
Amazing hotel, the perfect Key West vibe. Clean rooms, delicious breakfast. We will come back again

Reviewed on Nov 11, 2025

Opens in a new windowThe Gardens Hotel
The Marquesa Hotel

The Marquesa Hotel

600 Fleming Street Key West FL
$369 nightly
The price is $415 total per night from Nov 30 to Dec 1
$415 total
Nov 30 - Dec 1
Total with taxes and fees
This hotel features 3 outdoor pools, a restaurant, and a bar/lounge. Business travelers can take advantage of the laundry service. Self parking, a terrace, and ...
9.6/10 Exceptional! (1,002 reviews)
Absolutely incredible place to stay in key west. The staff was amazing and made sure that our stay was perfect. The rooms are clean, comfortable, and spacious. The location is in perfect walking distance to all the popular spots and the bar at the hotel made some amazing specialty drinks. We would ...

Reviewed on Nov 14, 2025

Opens in a new windowThe Marquesa Hotel
Duval House

Duval House

815 Duval St Key West FL
$161 nightly
The price is $178 total per night from Nov 25 to Nov 26
$178 total
Nov 25 - Nov 26
Total with taxes and fees
This bed & breakfast features a terrace, concierge services, and self parking. A garden, a picnic area, and express check-in are also on offer.
9.4/10 Exceptional! (1,002 reviews)
Small, clean cheerful room. Very helpful breakfast attendant. Pool & all amenities were perfect, grounds beautiful & relaxing.

Reviewed on Nov 15, 2025

Opens in a new windowDuval House
Silver Palms Inn

Silver Palms Inn

830 Truman Ave Key West FL
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $198 total per night from Nov 24 to Nov 25
$198 total
Nov 24 - Nov 25
Total with taxes and fees
An outdoor pool is featured at this hotel, along with free WiFi in public areas and luggage storage. Enjoy the free continental breakfast each morning. There's ...
9.2/10 Wonderful! (1,000 reviews)
Nice clean room, nice pool, convenient walk to Duval Street, pleasant staff, on site parking, great breakfast, what else could you ask for?.. recommended and will visit again.

Reviewed on Nov 13, 2025

Opens in a new windowSilver Palms Inn
The Marker Key West Harbor Resort

The Marker Key West Harbor Resort

200 William Street Key West FL
Fully refundableReserve now, pay when you stay
$263 nightly
The price is $296 total per night from Dec 2 to Dec 3
$296 total
Dec 2 - Dec 3
Total with taxes and fees
This smoke-free hotel features 3 outdoor pools, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in ...
9/10 Wonderful! (1,000 reviews)
Clean room. Beautiful property.

Reviewed on Nov 14, 2025

Opens in a new windowThe Marker Key West Harbor Resort
La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection

430 Duval St Key West FL
Fully refundableReserve now, pay when you stay
$242 nightly
The price is $272 total per night from Dec 14 to Dec 15
$272 total
Dec 14 - Dec 15
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the free WiFi in public areas, express ...
9/10 Wonderful! (268 reviews)
Staff very welcoming and friendly. The renovations are very beautiful. Love the new di ing area. Fanatstic murals.

Reviewed on Nov 19, 2025

Opens in a new windowLa Concha Key West, Autograph Collection
The Cabana Inn Key West - Adults Only

The Cabana Inn Key West - Adults Only

413 Applerouth Lane Key West FL
Fully refundableReserve now, pay when you stay
$184 nightly
The price is $208 total per night from Nov 30 to Dec 1
$208 total
Nov 30 - Dec 1
Total with taxes and fees
This guesthouse features an outdoor pool and a hot tub. Enjoy the free continental breakfast each morning. Self parking, a terrace, and a garden are also ...
8.8/10 Excellent! (1,004 reviews)
Great spot, 1/2 block off Duval Street in the heart of Old Town. Less than a 30 minute walk there everything. It’s clean, quiet and comfortable with a nice pool. Comp breakfast and happy hour.

Reviewed on Nov 16, 2025

Opens in a new windowThe Cabana Inn Key West - Adults Only
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More 4 star hotels in Key West Historic District

Key West Historic District Luxury Hotels

Do you want to stay at an elegant 5 star hotel for your next getaway? Do you want to be pampered like royalty? When you're ready, the Key West Historic District luxury hotels are the plush oasis you’ve been looking for.

Choose from the best luxury hotels in Key West Historic District to make your stay as comfortable and memorable as possible. Deluxe amenities await you upon check-in—perks like a heated pool, luxurious spa, and 24-hour reception service will cater to your every need, no matter the hour. If you’re tired from the day’s activities and don’t feel like wandering around to look for a meal, sit down to dinner at one of the high-end restaurants on property or contact room service for a sophisticated dining experience in the comfort of your own suite. Getting to and from the airport will be an easy task as well because most of these fancy hotels offer a free shuttle service for easy transportation.

We want you to enjoy your next vacation in style and the top luxury resorts in Key West Historic District will help you do just that. Browse Travelocity right now to find amazing deals on the best luxury hotels and 4 star hotels in Key West Historic District, and plan your next opulent escape.


Key West Historic District hotels essential information

Accommodation
1,757 hotels
Lowest Price
$178
Highest Price
$415
Popular hotels
The Marker Key West Harbor Resort, H2O Suites - Adults Only, La Concha Key West, Autograph Collection, Silver Palms Inn, Duval House, The Cabana Inn Key West - Adults Only, The Gardens Hotel, The Marquesa Hotel

Popular Luxury Stays in Key West Historic District

Recent Key West Historic District Hotel Reviews By Fellow Wanderers

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