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Top hotels close to Uruguay Street

Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.05 mi from Uruguay Street
$221 nightly
The price is $243 total per night
$243 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly dining, and babysitting. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi.
Pool
Spa

W Panama
Calle Aquilino de la Guardia & Calle 50 Panama City
Free Cancellation
Reserve now, pay when you stay
0.17 mi from Uruguay Street
$207 nightly
The price is $228 total per night
$228 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the 2 bars/lounges.
Pool
Hot Tub

Hilton Panama
Balboa Ave. and Aquilino De La Guardia Panama City
Free Cancellation
Reserve now, pay when you stay
0.24 mi from Uruguay Street
$201 nightly
The price is $222 total per night
$222 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This luxury hotel features an attached winery, a casino, and a full-service spa. Families will appreciate the onsite laundry facilities and babysitting. Enjoy a meal in one of the 4 restaurants and perks like free WiFi.
Pool
Spa

The Executive Hotel
Calle 52 Panama City Panama
Free Cancellation
0.24 mi from Uruguay Street
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included

Hyatt Regency Panama City
Calle 52 and Ricardo Arias Panama City
Free Cancellation
Reserve now, pay when you stay
0.28 mi from Uruguay Street
$157 nightly
The price is $172 total per night
$172 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference space, and free valet parking. Make the most of the 24-hour gym and steam room, and relax with drinks at one of the 2 bars/lounges.
Pool
Spa

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.37 mi from Uruguay Street
$95 nightly
The price is $104 total per night
$104 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and in-room childcare. Relax with a drink at one of the 2 bars/lounges and enjoy free perks like buffet breakfast and valet parking.
Pool
Breakfast included

AC Hotel by Marriott Panama City
Calle Ricardo Arias 14 Panama City
Free Cancellation
Reserve now, pay when you stay
0.39 mi from Uruguay Street
$107 nightly
The price is $118 total per night
$118 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the gym and perks like free self parking.
Pool
Parking included

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.4 mi from Uruguay Street
$109 nightly
The price is $120 total per night
$120 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included

Megapolis Hotel Panamá
Avenida Balboa Panama City
Free Cancellation
Reserve now, pay when you stay
0.51 mi from Uruguay Street
$257 nightly
The price is $283 total per night
$283 total
Dec 31 - Jan 1, 2026
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.6 mi from Uruguay Street
$116 nightly
The price is $129 total per night
$129 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. You'll appreciate the gym, bar/lounge, and coffee shop.
Pool
Spa

Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.68 mi from Uruguay Street
$108 nightly
The price is $119 total per night
$119 total
Jan 16 - Jan 17, 2026
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included

Principe Hotel and Suites
Via Argentina Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.7 mi from Uruguay Street
$55 nightly
The price is $61 total per night
$61 total
Dec 30 - Dec 31
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Free self parking, a coffee shop, and a terrace are also offered.
Pool
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Uruguay Street hotels essential information
Accommodation | 1,671 hotels |
|---|---|
Lowest Price | $61 |
Highest Price | $283 |
Popular hotels | Hotel Riu Plaza Panama, Waldorf Astoria Panama, Megapolis Hotel Panamá, Las Americas Golden Tower Panama, W Panama, Hotel El Panama by Faranda Grand, a member of Radisson Individuals, Plaza Paitilla Inn Hotel, Hyatt Regency Panama City, The Executive Hotel, Principe Hotel and Suites, AC Hotel by Marriott Panama City, Hilton Panama |
Recent Uruguay Street hotel reviews by fellow wanderers

Hotel Riu Plaza Panama
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Recommend I would stay again "
A verified traveler stayed at Hotel Riu Plaza Panama
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