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Top hotels close to Uruguay Street

Waldorf Astoria Panama
47th St. & Uruguay Street Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.05 mi from Uruguay Street
$180 nightly
The price is $198 total per night
$198 total
Dec 16 - Dec 17
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly dining, and babysitting. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi.

W Panama
Calle Aquilino de la Guardia & Calle 50 Panama City
Free Cancellation
Reserve now, pay when you stay
0.17 mi from Uruguay Street
$199 nightly
The price is $219 total per night
$219 total
Dec 19 - Dec 20
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the 2 bars/lounges.

Hilton Panama
Balboa Ave. and Aquilino De La Guardia Panama City
Free Cancellation
Reserve now, pay when you stay
0.24 mi from Uruguay Street
$186 nightly
The price is $205 total per night
$205 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
This luxury hotel features an attached winery, a casino, and a full-service spa. Families will appreciate the onsite laundry facilities and babysitting. Enjoy a meal in one of the 4 restaurants and perks like free WiFi.
Pool
Spa

The Executive Hotel
Calle 52 Panama City Panama
Free Cancellation
0.24 mi from Uruguay Street
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Enjoy the gym and free perks like buffet breakfast and free self parking.
Pool
Breakfast included

Studio Coliving
Av. Ricardo Arango y, Av. Federico Boyd Panama City Panama
0.27 mi from Uruguay Street
$44 nightly
The price is $49 total per night
$49 total
Dec 9 - Dec 10
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. There's a 24-hour gym on site, and laundry facilities and concierge services are also offered.

Hyatt Regency Panama City
Calle 52 and Ricardo Arias Panama City
Free Cancellation
Reserve now, pay when you stay
0.28 mi from Uruguay Street
$135 nightly
The price is $149 total per night
$149 total
Dec 13 - Dec 14
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference space, and free valet parking. Make the most of the outdoor pool and steam room, and relax with drinks at one of the 2 bars/lounges.
Pool
Spa

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.4 mi from Uruguay Street
$122 nightly
The price is $135 total per night
$135 total
Dec 9 - Dec 10
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. Relax with a drink at the bar/lounge and enjoy the free buffet breakfast each morning.
Pool
Breakfast included

Megapolis Hotel Panamá
Avenida Balboa Panama City
Free Cancellation
Reserve now, pay when you stay
0.51 mi from Uruguay Street
$122 nightly
The price is $135 total per night
$135 total
Dec 21 - Dec 22
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free valet parking. Relax with a drink at one of the 3 bars/lounges and enjoy free perks like buffet breakfast and free self parking.
Pool
Hot Tub

Decapolis Hotel Panama City
Avenida Balboa Con Multicentro Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.57 mi from Uruguay Street
$112 nightly
The price is $123 total per night
$123 total
Dec 10 - Dec 11
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 2 restaurants. Traveling on business? Take advantage of the free WiFi in public areas, express check-out, and free valet parking. Enjoy the outdoor pool and free buffet breakfast each morning.

Las Americas Golden Tower Panama
Av. Balboa con Calle 53 Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.6 mi from Uruguay Street
$161 nightly
The price is $179 total per night
$179 total
Dec 14 - Dec 15
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center and free WiFi in public areas. You'll appreciate the gym, bar/lounge, and coffee shop.

Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.68 mi from Uruguay Street
$158 nightly
The price is $174 total per night
$174 total
Dec 9 - Dec 10
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the gym and free perks like buffet breakfast and free self parking.

Principe Hotel and Suites
Via Argentina Panama City Panama
Free Cancellation
Reserve now, pay when you stay
0.7 mi from Uruguay Street
$50 nightly
The price is $55 total per night
$55 total
Dec 20 - Dec 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, and airport shuttle. Free self parking, a coffee shop, and a terrace are also offered.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Uruguay Street hotels essential information
Accommodation | 1,655 hotels |
|---|---|
Lowest Price | $49 |
Highest Price | $219 |
Popular hotels | Hotel Riu Plaza Panama, Waldorf Astoria Panama, Las Americas Golden Tower Panama, Megapolis Hotel Panamá, W Panama, The Executive Hotel, Hyatt Regency Panama City, Plaza Paitilla Inn Hotel, Principe Hotel and Suites, Decapolis Hotel Panama City, Hilton Panama, Studio Coliving |
Recent Uruguay Street hotel reviews by fellow wanderers

Decapolis Hotel Panama City
5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Todo bien"
A verified traveler stayed at Decapolis Hotel Panama City
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