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Top hotels in Santa Clara

The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
Fully refundable
$81 nightly
The price is $89 total per night from Apr 30 to May 1
$89 total
Apr 30 - May 1
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Overall, our stay was fine for the one night we stayed. The hotel arranged transportation from & to the airport but were a little difficult to contact. We ended up calling them from the US to make the arrangements. The breakfast was good. It's a city location. The room set off my dust mite allergy ...

Reviewed on Apr 1, 2026

Opens in a new windowThe Executive Hotel
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $162 total per night from Apr 27 to Apr 28
$162 total
Apr 27 - Apr 28
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Room was great, clean, friendly staff, and very convenient location.

Reviewed on Apr 2, 2026

Opens in a new windowHotel Riu Plaza Panama
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from Apr 3 to Apr 4
$62 total
Apr 3 - Apr 4
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
I really enjoyed my stay. I went there on the 24th of march and left today, which is the 31st of march 2026. There restaurants where so near by and a food store next door the pool was good the rooms where very nice. The only thing was missing was having a microwave in the rooms other wise the rooms ...

Reviewed on Apr 1, 2026

Opens in a new windowPrincipe Hotel and Suites
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$281 nightly
The price is $309 total per night from Apr 20 to Apr 21
$309 total
Apr 20 - Apr 21
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Clean room and helpful staff

Reviewed on Mar 30, 2026

Opens in a new windowWaldorf Astoria Panama
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
Fully refundableReserve now, pay when you stay
$269 nightly
The price is $296 total per night from May 2 to May 3
$296 total
May 2 - May 3
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...
Breakfast is worth it in the morning! Nice view out of the hotel. The W is next to everything.

Reviewed on Mar 30, 2026

Opens in a new windowW Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $103 total per night from Apr 9 to Apr 10
$103 total
Apr 9 - Apr 10
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
I didnt use the breakfast nor parking, but the casino was ok.

Reviewed on Apr 2, 2026

Opens in a new windowWaymore Hotel Spa & Casino
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$130 nightly
The price is $143 total per night from Apr 27 to Apr 28
$143 total
Apr 27 - Apr 28
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
Complimentary food was not kid friendly…only mini hotdogs

Reviewed on Mar 31, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $148 total per night from May 1 to May 2
$148 total
May 1 - May 2
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
Great breakfast great spa

Reviewed on Apr 1, 2026

Opens in a new windowSheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $125 total per night from Apr 9 to Apr 10
$125 total
Apr 9 - Apr 10
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
Breakfast was awesome. Room. AC very noisy and toilet kept running.

Reviewed on Mar 30, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Clara Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Santa Clara area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Santa Clara to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Santa Clara are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Santa Clara hotel reviews by fellow wanderers

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Posted 4 hours ago
Travelocity Verified Review
"Room was great, clean, friendly staff, and very convenient location."
A verified traveler stayed at Hotel Riu Plaza Panama
Hotel Riu Plaza Panama

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