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Top hotels in Santa Clara

The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
$93 nightly
The price is $102 total per night from Feb 22 to Feb 23
$102 total
Feb 22 - Feb 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Good customer service

Reviewed on Feb 13, 2026

Opens in a new windowThe Executive Hotel
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $151 total per night from Mar 3 to Mar 4
$151 total
Mar 3 - Mar 4
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, ...
Room was spotless. Staff very courteous.

Reviewed on Feb 10, 2026

Opens in a new windowHotel Riu Plaza Panama
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $202 total per night from Mar 7 to Mar 8
$202 total
Mar 7 - Mar 8
Total with taxes and fees
This luxury hotel features 2 restaurants, 3 hot tubs, and an outdoor pool. Make the most of the gym and a rooftop terrace, and relax with drinks at one of the ...
Room

Reviewed on Feb 10, 2026

Opens in a new windowW Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $98 total per night from Feb 18 to Feb 19
$98 total
Feb 18 - Feb 19
Total with taxes and fees
A full-service spa, an outdoor pool, and a restaurant are all featured at this smoke-free bed & breakfast. Traveling on business? Take advantage of the free ...
Staff was friendly, room was clean and for the price, it was worth it.

Reviewed on Feb 12, 2026

Opens in a new windowWaymore Hotel Spa & Casino
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
$221 nightly
The price is $243 total per night from Mar 7 to Mar 8
$243 total
Mar 7 - Mar 8
Total with taxes and fees
A full-service spa, 2 restaurants, and an outdoor pool are all featured at this luxury hotel. Families will appreciate the onsite laundry facilities, kid-friendly ...
Staff was friendly and helpful. Amenities were great and location was perfect.

Reviewed on Feb 10, 2026

Opens in a new windowWaldorf Astoria Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$176 nightly
The price is $194 total per night from Feb 25 to Feb 26
$194 total
Feb 25 - Feb 26
Total with taxes and fees
A full-service spa, an indoor pool, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
Well managed luxury hotel

Reviewed on Feb 10, 2026

Opens in a new windowLas Americas Golden Tower Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$134 nightly
The price is $147 total per night from Feb 23 to Feb 24
$147 total
Feb 23 - Feb 24
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Families will appreciate the children's pool, onsite laundry facilities, and babysitting. ...
Staff very friendly. Nice hotel

Reviewed on Feb 13, 2026

Opens in a new windowCrowne Plaza Panama Airport by IHG
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $139 total per night from Feb 27 to Feb 28
$139 total
Feb 27 - Feb 28
Total with taxes and fees
A full-service spa, 3 restaurants, and 3 outdoor tennis courts are all featured at this smoke-free resort. Families will appreciate the playground, kid-friendly ...
Room was always clean. Staff was courteous it was also close proximity to Multiplaza mall which was great. Breakfast was ok.

Reviewed on Feb 9, 2026

Opens in a new windowSheraton Grand Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
$108 nightly
The price is $119 total per night from Feb 23 to Feb 24
$119 total
Feb 23 - Feb 24
Total with taxes and fees
This smoke-free hotel features a casino, a full-service spa, and 3 restaurants. Families will appreciate the children's pool, onsite laundry facilities, and ...
The room was cleaned every day, but the bathtub is very old and nasty because there's so much filth accumulated that it can't be removed no matter what they do Room service and front desk was outstanding and very patient I will book my next stay in Panamá right here

Reviewed on Feb 13, 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Clara Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Santa Clara area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Santa Clara to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Santa Clara are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Santa Clara hotel reviews by fellow wanderers

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