Book Hotels in Mesilla, NM

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility

Top hotels

Casita Azul, Mesilla Plaza Only Steps Away

Casita Azul, Mesilla Plaza Only Steps Away

Mesilla
This vacation home featured laundry facilities and barbecue grills.
"Fabulous! Highly recommend for a cozy and comfortable stay. Love the traditional folk art decor. Charming to the highest degree!"

Reviewed on Jun 19, 2025

Casita Azul, Mesilla Plaza Only Steps Away
Josefina's King Suite in Historic Old Mesilla Plaza.

Josefina's King Suite in Historic Old Mesilla Plaza.

2 out of 5
Mesilla
Stay at this apartment in Mesilla. Enjoy air conditioning. Popular attractions San Albino Basilica and Mesillia Plaza are located nearby.
"My husband and I love staying at Josephina’s! It’s comfy, close to shopping and dining."

Reviewed on Jun 13, 2025

Josefina's King Suite in Historic Old Mesilla Plaza.
Charming Casita in historic Town of Mesilla,  NM  2392 Calle de Parian

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

Mesilla
This vacation home features a garden, laundry facilities, and barbecue grills.
"Super located in the heart of Old Mesilla. The Casita was absolutely perfect, well-stocked (kitchen, bath, etc), and a welcoming. Yolanda's communication prior to our stay was very responsive and inviting. She even left a welcoming gift for us -- some fruit, chips and local salsa. We were literally ..."

Reviewed on Jun 8, 2025

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

3.5 out of 5
705 S Telshor Blvd, Las Cruces, NM
Fully refundableReserve now, pay when you stay
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling for business? Take advantage of the 24-hour business center, ...
"Just the receptionist little mad I guess she said was very tired"

Reviewed on Jun 22, 2025

Hotel Encanto de Las Cruces
Best Western Mission Inn

Best Western Mission Inn

2.5 out of 5
1765 S Main St, Las Cruces, NM
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
"We appreciated the hotel room cleanliness as well as the friendliness of the staff! Would recommend and stay here again!"

Reviewed on Jun 21, 2025

Best Western Mission Inn
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

3 out of 5
1500 Hickory Dr, Las Cruces, NM
Fully refundableReserve now, pay when you stay
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
"Pet friendly and very clean"

Reviewed on Jun 24, 2025

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

2.5 out of 5
755 Avenida De Mesilla, Las Cruces, NM
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"I"

Reviewed on Jun 21, 2025

Days Inn by Wyndham Las Cruces
Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces

3 out of 5
201 E University Avenue, I-10 Exit 142, Las Cruces, NM
Fully refundableReserve now, pay when you stay
A full-service spa and an indoor pool are featured at this smoke-free hotel. Traveling on business? Take advantage of the free WiFi in public areas, conference ...
"Nice and quit"

Reviewed on Jun 22, 2025

Ramada Hotel & Conference Center by Wyndham Las Cruces
La Quinta Inn by Wyndham Las Cruces Mesilla Valley

La Quinta Inn by Wyndham Las Cruces Mesilla Valley

3 out of 5
790 Avenida De Mesilla, Las Cruces, NM
Fully refundableReserve now, pay when you stay
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the conference space and free ...
"They accommodated my every need with smiles"

Reviewed on Jun 14, 2025

La Quinta Inn by Wyndham Las Cruces Mesilla Valley
Don't see what you're looking for?
See all available properties in Mesilla
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mesilla Hotel & Travel Guide\n

Researching for your trip to Mesilla? There is a great range of hotels to choose from. Find inspiration with no less than 32 hotel options within easy driving distance of Mesilla's center on Travelocity's informative and up-to-date lodging guide.

Hotels that you can find within a quick walk of central Mesilla, are the Springhill Suites By Marriott Las Cruces and La Quinta Inn & Suites Las Cruces Organ Mountain.

Investigate the Staybridge Suites Las Cruces as well as the Holiday Inn Express Hotel and Suites Las Cruces. The Staybridge Suites Las Cruces is located only 6 miles (10 kilometers) outside of the middle of Mesilla. The Holiday Inn Express Hotel and Suites Las Cruces, can be found 2 miles (3 kilometers) away. Another two hotel options worth checking out around Mesilla include the Hampton Inn & Suites Las Cruces I-25 and the Hotel Encanto de Las Cruces.

Keen on seeing more of the desert landscapes this area features? Why not book a few nights in other locations in Southwestern New Mexico? Have fun hiking or visit the region's local cultural and natural sights. Comfortable accommodations can be booked.

Are you looking for activities? Spend the day visiting Mesilla Valley Mall and Las Cruces Museum of Art, in Las Cruces, 8 miles (13 kilometers) to the north of Mesilla. If you spend a few nights in Las Cruces, be sure to check out the Holiday Inn Express & Suites Las Cruces North and Towneplace Suites by Marriott Las Cruces. 35 miles (57 kilometers) to the southeast of Mesilla, you'll find Sunland Park, which is home to the SpringHill Suites by Marriott El Paso and Country Inn & Suites by Carlson El Paso Sunland Park, TX. The Western Playland Amusement Park and Sunland Park Racetrack and Casino are other frequented attractions to check out while in Sunland Park.

Prior to departing Southwestern New Mexico, be sure you are able to watch some local teams. Get to Sun Bowl Stadium, which you can find to the southeast of Mesilla. Stay near the action at the DoubleTree by Hilton El Paso Downtown or the Hilton Garden Inn El Paso / University.

Located 40 miles (65 kilometers) from Mesilla's downtown is El Paso International Airport. Stay nearby at Homewood Suites by Hilton El Paso Airport or Holiday Inn Express & Suites El Paso Airport Area.

Frequently asked questions

What are the top kid-friendly hotels in Mesilla?
Take some of the troubles out of traveling with little ones by opting for a family-friendly Mesilla hotel. From useful amenities to extra services, these properties offer perks that'll make your visit run like a dream: You'll be well taken care of at Charming Couples Casita, Walk to Old Mesilla Plaza. It comes with pet-friendly facilities, free WiFi and a talent for making families feel at home. Alternatively, spend your Mesilla break at Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian. Make the most of animal viewing activities, a fireplace and more here.
Where can I find cheap hotels in Mesilla?
At Travelocity you'll find really nice hotels in Mesilla at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mesilla rather than in Mesilla. We may find you even better rates, too.
How do I find the best Mesilla hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mesilla then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mesilla?
The cheapest hotel in Mesilla is . This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mesilla?
There are 341 hotels in Mesilla on Travelocity.
What are the best hotels in Mesilla?
Mesilla has so many great hotels to choose from at Travelocity --- and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mesilla for you!
When is the best time to visit Mesilla?
If you want the joy of a fun-filled trip in peak season, visit Mesilla during March, May and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Mesilla?
Based on historic data is usually the cheapest month to visit Mesilla. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mesilla?
There are multiple hotels in Mesilla that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mesilla. We have plenty of kid-friendly hotels in Mesilla to choose from on Travelocity!
Why book a hotel in Mesilla through Travelocity?
Because we have the top hotels in Mesilla! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mesilla on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

Recent Mesilla hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity

Explore More Ways to Travel with Travelocity