Book Hotels in Dona Ana, NM
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Top Dona Ana hotels

Drury Inn & Suites Las Cruces
1631 Hickory Loop Las Cruces NM
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $109 total per night from Aug 23 to Aug 24
$109 total
Aug 23 - Aug 24
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
"Everything was great! The breakfast buffet was good. The kickback with drinks was amazing. Loved the chicken fajitas."
Reviewed on Aug 18, 2026

Hotel Encanto de Las Cruces
705 S Telshor Blvd Las Cruces NM
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $154 total per night from Sep 7 to Sep 8
$154 total
Sep 7 - Sep 8
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling for business? Take advantage of the 24-hour business center, ...
"The price point is comparable to a chain hotel but the experience is much more inviting if having to stay in a hotel. The rooms are basic but thoughtful with the theme of NM and really roomy Beds are comfortable Bathroom spacious AC cooled well and it was quiet building Didn’t have much of a view ..."
Reviewed on Aug 18, 2026

Holiday Inn Express & Suites Las Cruces North by IHG
2142 Telshor Ct Las Cruces NM
Fully refundable
$118 nightly
The price is $136 total per night from Aug 30 to Aug 31
$136 total
Aug 30 - Aug 31
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
"Tried canceling because of emergency and they wouldn't. So boom. 1 star for everything. Ive worked in hotel business. Believe me when I say EVERY reservation can be canceled."
Reviewed on Aug 18, 2026

Days Inn by Wyndham Las Cruces
755 Avenida De Mesilla Las Cruces NM
Fully refundableReserve now, pay when you stay
$48 nightly
The price is $57 total per night from Aug 20 to Aug 21
$57 total
Aug 20 - Aug 21
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
"Will stay there again was very nice"
Reviewed on Aug 18, 2026

Ramada Hotel & Conference Center by Wyndham Las Cruces
201 E University Avenue Las Cruces NM
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $92 total per night from Sep 1 to Sep 2
$92 total
Sep 1 - Sep 2
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free WiFi and free self parking. Traveling on business? Take advantage of the conference center and conference ...
"The hotel is super old. I honestly did not want to stay there but we had already arrived and were late to head to a wedding. It has a creepy feeling and not kept up at all. Needs to be remodeled. The continental breakfast was blah. Glass door broken not fixed at one of the entrances. We will not ..."
Reviewed on Aug 17, 2026

Comfort Suites University Las Cruces
2101 S Triviz Drive Las Cruces NM
Fully refundable
$83 nightly
The price is $97 total per night from Sep 13 to Sep 14
$97 total
Sep 13 - Sep 14
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
"The check in receptionist was great, room was semi clean room was sorta older, carpet wasnt the greatest and bathroom door was hard to open thought we were locked in but overall bathroom was sparkly cleaned. old food was left in the fridge we were told to clean it out ourselves, which we did, breakfast ..."
Reviewed on Aug 18, 2026

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
1500 Hickory Dr Las Cruces NM
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $67 total per night from Sep 13 to Sep 14
$67 total
Sep 13 - Sep 14
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...

Comfort Suites Las Cruces I-25 North
236 N Telshor Blvd. Las Cruces NM
Fully refundable
$111 nightly
The price is $128 total per night from Aug 30 to Aug 31
$128 total
Aug 30 - Aug 31
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...

Courtyard by Marriott Las Cruces at NMSU
456 East University Avenue Las Cruces NM
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $155 total per night from Aug 22 to Aug 23
$155 total
Aug 22 - Aug 23
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent Dona Ana hotel reviews by fellow wanderers

Days Inn by Wyndham Las Cruces
5 out of 5
Posted 12 hours ago
Travelocity Verified Review
"Will stay there again was very nice"
A verified traveler stayed at Days Inn by Wyndham Las Cruces
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