Book Hotels in Mesilla, NM

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Top Mesilla hotels

Casita Azul, Mesilla Plaza Only Steps Away

Casita Azul, Mesilla Plaza Only Steps Away

Mesilla
This vacation home featured laundry facilities and barbecue grills.
This is the second time we have stayed at this lovely Casita. It’s roomy and comfortable with a full kitchen and laundry. The host was very helpful with providing everything we needed for our stay and gracious with gifting us a nice bottle of wine waiting for us on our arrival. The location is perfect ...

Reviewed on Oct 6, 2025

Opens in a new windowCasita Azul, Mesilla Plaza Only Steps Away
Josefina's King Suite in Historic Old Mesilla Plaza.

Josefina's King Suite in Historic Old Mesilla Plaza.

2 out of 5
Mesilla
$170 nightly
The price is $184 total per night from Nov 3 to Nov 4
$184 total
Nov 3 - Nov 4
Total with taxes and fees
Stay at this apartment in Mesilla. Enjoy air conditioning. Popular attractions San Albino Basilica and Mesillia Plaza are located nearby.
Great!!!

Reviewed on Oct 6, 2025

Opens in a new windowJosefina's King Suite in Historic Old Mesilla Plaza.
Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

3 out of 5
1631 Hickory Loop, Las Cruces, NM
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $109 total per night from Nov 9 to Nov 10
$109 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the hot tub and ...
The free evening appetizer buffet and drinks were way more than we expected. The food was replenished in a time manner and kept warm, which is rare for this type of presentation. The staff was great at keeping the service area clean.

Reviewed on Oct 28, 2025

Opens in a new windowDrury Inn & Suites Las Cruces
Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North

2.5 out of 5
236 N Telshor Blvd., Las Cruces, NM
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $131 total per night from Nov 9 to Nov 10
$131 total
Nov 9 - Nov 10
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Enjoy the hot ...
I really enjoyed my stay, it was refreshing how clean and friendly the staff were!

Reviewed on Oct 26, 2025

Opens in a new windowComfort Suites Las Cruces I-25 North
Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

3.5 out of 5
705 S Telshor Blvd, Las Cruces, NM
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $164 total per night from Nov 3 to Nov 4
$164 total
Nov 3 - Nov 4
Total with taxes and fees
A nightclub, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling for business? Take advantage of the 24-hour business center, ...
I am from Las Cruces, we stay at Encanto everytime we come home.

Reviewed on Oct 28, 2025

Opens in a new windowHotel Encanto de Las Cruces
Best Western Mission Inn

Best Western Mission Inn

2.5 out of 5
1765 S Main St, Las Cruces, NM
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $89 total per night from Nov 4 to Nov 5
$89 total
Nov 4 - Nov 5
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and free self parking. Business travelers can take advantage of the business ...
Front desk staff was friendly and courteous. The room was great, and the area was quiet. I will stay there again when in Las Cruces, NM

Reviewed on Oct 27, 2025

Opens in a new windowBest Western Mission Inn
Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

2.5 out of 5
755 Avenida De Mesilla, Las Cruces, NM
Fully refundableReserve now, pay when you stay
$48 nightly
The price is $57 total per night from Nov 4 to Nov 5
$57 total
Nov 4 - Nov 5
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free on-the-go breakfast, free WiFi, and free self parking. Business travelers can take advantage of the ...
I always stay at Days Inn. It is close to the business

Reviewed on Oct 27, 2025

Opens in a new windowDays Inn by Wyndham Las Cruces
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

3 out of 5
1500 Hickory Dr, Las Cruces, NM
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $70 total per night from Dec 3 to Dec 4
$70 total
Dec 3 - Dec 4
Total with taxes and fees
An outdoor pool, free self parking, and laundry facilities are featured at this hotel. Guests will appreciate free perks like continental breakfast and WiFi ...
Friendly staff

Reviewed on Oct 29, 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Comfort Suites University Las Cruces

Comfort Suites University Las Cruces

2.5 out of 5
2101 S Triviz Drive, Las Cruces, NM
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $92 total per night from Nov 16 to Nov 17
$92 total
Nov 16 - Nov 17
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
This is our Go to hotel in Las Cruces. Always clean and friendly. They have a good breakfast as well.

Reviewed on Oct 30, 2025

Opens in a new windowComfort Suites University Las Cruces
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Mesilla Hotel & Travel Guide\n

Researching for your trip to Mesilla? There is a great range of hotels to choose from. Find inspiration with no less than 32 hotel options within easy driving distance of Mesilla's center on Travelocity's informative and up-to-date lodging guide.

Hotels that you can find within a quick walk of central Mesilla, are the Springhill Suites By Marriott Las Cruces and La Quinta Inn & Suites Las Cruces Organ Mountain.

Investigate the Staybridge Suites Las Cruces as well as the Holiday Inn Express Hotel and Suites Las Cruces. The Staybridge Suites Las Cruces is located only 6 miles (10 kilometers) outside of the middle of Mesilla. The Holiday Inn Express Hotel and Suites Las Cruces, can be found 2 miles (3 kilometers) away. Another two hotel options worth checking out around Mesilla include the Hampton Inn & Suites Las Cruces I-25 and the Hotel Encanto de Las Cruces.

Keen on seeing more of the desert landscapes this area features? Why not book a few nights in other locations in Southwestern New Mexico? Have fun hiking or visit the region's local cultural and natural sights. Comfortable accommodations can be booked.

Are you looking for activities? Spend the day visiting Mesilla Valley Mall and Las Cruces Museum of Art, in Las Cruces, 8 miles (13 kilometers) to the north of Mesilla. If you spend a few nights in Las Cruces, be sure to check out the Holiday Inn Express & Suites Las Cruces North and Towneplace Suites by Marriott Las Cruces. 35 miles (57 kilometers) to the southeast of Mesilla, you'll find Sunland Park, which is home to the SpringHill Suites by Marriott El Paso and Country Inn & Suites by Carlson El Paso Sunland Park, TX. The Western Playland Amusement Park and Sunland Park Racetrack and Casino are other frequented attractions to check out while in Sunland Park.

Prior to departing Southwestern New Mexico, be sure you are able to watch some local teams. Get to Sun Bowl Stadium, which you can find to the southeast of Mesilla. Stay near the action at the DoubleTree by Hilton El Paso Downtown or the Hilton Garden Inn El Paso / University.

Located 40 miles (65 kilometers) from Mesilla's downtown is El Paso International Airport. Stay nearby at Homewood Suites by Hilton El Paso Airport or Holiday Inn Express & Suites El Paso Airport Area.

Frequently asked questions

What are the top kid-friendly hotels in Mesilla?
Take some of the troubles out of traveling with little ones by opting for a family-friendly Mesilla hotel. From useful amenities to extra services, these properties offer perks that'll make your visit run like a dream: You'll be well taken care of at Charming Couples Casita, Walk to Old Mesilla Plaza. It comes with pet-friendly facilities, free WiFi and a talent for making families feel at home. Alternatively, spend your Mesilla break at Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian. Make the most of animal viewing activities, a fireplace and more here.
Where can I find cheap hotels in Mesilla?
At Travelocity you'll find really nice hotels in Mesilla at great prices. We source incredible prices with our trusted partners, so you have a tempting selection of cheap hotels to choose from. If you can be flexible on dates and location, consider staying at a hotel near Mesilla rather than in Mesilla. We may find you even better rates, too.
How do I find the best Mesilla hotel deals?
Simple! On Travelocity, look through the fantastic offers we've already found in Mesilla then use our filters to find a great deal that's perfect for you. Enter your travel dates, select the number of rooms you need, and we'll do the rest. You can get great discounts on flights and car hire, too, when you bundle.
How much does it cost to stay in a hotel in Mesilla?
The cheapest hotel in Mesilla is $57. This price was available within the past 7 days, for stays with a check-in date within the next year. Of course, the price you pay depends on your dates of travel, the length of your stay, and the hotel's location. Prices and availability are subject to change. Additional terms apply.
How many hotels are in Mesilla?
There are 355 hotels in Mesilla on Travelocity.
What are the best hotels in Mesilla?
Mesilla has so many great hotels to choose from at Travelocity — and it's so easy to find the perfect one. Just choose one of our popular pre-selected hotels with great reviews, or you can refine your search to build your ideal stay. Simply filter hotels based on price or star rating, or select properties with a pool, a hot tub, or a range of other amenities and pick the best place to stay in Mesilla for you!
When is the best time to visit Mesilla?
If you want the joy of a fun-filled trip in peak season, visit Mesilla during March, May and July. If you'd prefer the peace of off-season, book a stay during quieter months, such as September, October and December.
When is the cheapest time to stay in Mesilla?
Based on historic data is usually the cheapest month to visit Mesilla. However, we have incredible deals all year round, so we're confident you'll find a room in your budget whenever you choose to travel.
Are there any great family-friendly hotels in Mesilla?
There are multiple hotels in Mesilla that will please the whole family. Do you need adjoining rooms, babysitting services or a swimming pool? We've got you covered. Use our family filter to narrow your search down and use guest reviews to help you pick the perfect place for your next family trip to Mesilla. We have plenty of kid-friendly hotels in Mesilla to choose from on Travelocity!
Why book a hotel in Mesilla through Travelocity?
Because we have the top hotels in Mesilla! We want to help you travel more and worry less. That's why we've put the most amazing hotel, car rental, and flight deals in one place. When you search for hotels with us, you know you're getting fantastic prices with no hidden fees and free cancellation on most properties up to 24 hours before your stay. If you become a Travelocity member, you also get exclusive member discounts. Sign up today!
How do I cancel my hotel booking in Mesilla on Travelocity?
Canceling your booking with Travelocity is easy. Sign into your account and select My Trips. Here, you will see your cancellation options. We offer free cancellation on many properties.

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