Find a Hotel in Isle of Palms South

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Top hotels in Isle of Palms South

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
1515 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $149 total per night from Feb 8 to Feb 9
$149 total
Feb 8 - Feb 9
Total with taxes and fees
This hotel features 2 outdoor pools, a 24-hour gym, and a restaurant. Unwind with a drink at one of the 2 bars/lounges and enjoy free perks like full breakfast ...
Clean room , great staff

Reviewed on Jan 11, 2026

Opens in a new windowHampton Inn Jacksonville Beach/Oceanfront
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $169 total per night from Jan 21 to Jan 22
$169 total
Jan 21 - Jan 22
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Friendly staff, clean rooms and great atmosphere!

Reviewed on Jan 19, 2026

Opens in a new windowMargaritaville Jacksonville Beach
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
$164 nightly
The price is $186 total per night from Jan 31 to Feb 1
$186 total
Jan 31 - Feb 1
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
Very clean and comfortable room.

Reviewed on Jan 18, 2026

Opens in a new windowHyatt Regency Jacksonville
San Marco Inn East

San Marco Inn East

3 out of 5
3558 Phillips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $70 total per night from Jan 25 to Jan 26
$70 total
Jan 25 - Jan 26
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, dry cleaning, and laundry facilities are also on offer.
Everything was great like always clean friendly staff

Reviewed on Jan 13, 2026

Opens in a new windowSan Marco Inn East
Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk

3.5 out of 5
1515 Prudential Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $132 total per night from Jan 24 to Jan 25
$132 total
Jan 24 - Jan 25
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
Room was clean, lobby spacious, TV channel selection good. Also has Netflix, Amazon Prime, and YouTube. Free coffee in the lobby in the morning and coffee machine in the room. Only issue no safe in room.

Reviewed on Jan 17, 2026

Opens in a new windowSouthbank Hotel by Marriott Jacksonville Riverwalk
Comfort Suites Baymeadows Near Butler Blvd

Comfort Suites Baymeadows Near Butler Blvd

3 out of 5
8277 Western Way Cir Jacksonville FL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $115 total per night from Jan 25 to Jan 26
$115 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool and a gym. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Guests will ...
Enjoyed comfort suites. No matter where we stay they are always excellant

Reviewed on Jan 9, 2026

Opens in a new windowComfort Suites Baymeadows Near Butler Blvd
Midtown Lodge

Midtown Lodge

2.5 out of 5
4141 Philips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $67 total per night from Jan 27 to Jan 28
$67 total
Jan 27 - Jan 28
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. The front desk is staffed around-the-clock and laundry facilities are ...
Staff is nice

Reviewed on Jan 14, 2026

Opens in a new windowMidtown Lodge
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road Jacksonville FL
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jan 25 to Jan 26
$79 total
Jan 25 - Jan 26
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Staff was very accommodating and pleasant!

Reviewed on Jan 16, 2026

Opens in a new windowWyndham Garden Jacksonville
DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront

4 out of 5
1201 Riverplace Boulevard Jacksonville FL
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $129 total per night from Feb 1 to Feb 2
$129 total
Feb 1 - Feb 2
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an outdoor pool, and a 24-hour gym. Relax with a drink at one of the 2 bars/lounges and get perks like free WiFi. ...
Clean room and beautiful view

Reviewed on Jan 12, 2026

Opens in a new windowDoubleTree by Hilton Hotel Jacksonville Riverfront
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isle of Palms South Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Isle of Palms South area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Isle of Palms South to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Isle of Palms South are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

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