Find a Hotel in Isle of Palms South

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Oct 23 - Oct 25
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Top hotels in Isle of Palms South

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

2.5 out of 5
1220 Marsh Landing Pkwy Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $134 total per night from Nov 15 to Nov 16
$134 total
Nov 15 - Nov 16
Total with taxes and fees
This hotel features an outdoor pool and a 24-hour gym. Traveling for business? Take advantage of the free WiFi in public areas, express check-in, and conference ...
"walls between rooms are paper thin"

Reviewed on Oct 23, 2026

Opens in a new windowHampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road Jacksonville FL
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $85 total per night from Oct 26 to Oct 27
$85 total
Oct 26 - Oct 27
Total with taxes and fees
This hotel features an outdoor pool, a gym, and a restaurant. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"This property is in disrepair. The only good thing was plenty of parking & my husband liked the restaurant next door (although who doesn't give napkins for ribs on a takeout order). The rooms smelled moldy, It was so bad (3rd floor) that we picked up some of the smell in our luggage and now I can't ..."

Reviewed on Oct 23, 2026

Opens in a new windowWyndham Garden Jacksonville
Weekly Inn

Weekly Inn

2 out of 5
8016 Arlington Expressway Service Rd Jacksonville FL
Fully refundableReserve now, pay when you stay
$50 nightly
The price is $56 total per night from Oct 28 to Oct 29
$56 total
Oct 28 - Oct 29
Total with taxes and fees
A 24-hour gym, free self parking, and laundry facilities are featured at this motel. WiFi in public areas is free. A terrace is also provided.
"Good"

Reviewed on Oct 22, 2026

Opens in a new windowWeekly Inn
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $203 total per night from Oct 25 to Oct 26
$203 total
Oct 25 - Oct 26
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
Opens in a new windowMargaritaville Jacksonville Beach
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
$168 nightly
The price is $190 total per night from Nov 22 to Nov 23
$190 total
Nov 22 - Nov 23
Total with taxes and fees
This smoke-free hotel includes 3 restaurants, an outdoor pool, and a 24-hour gym. Traveling on business? Take advantage of the business center, free WiFi in ...
Opens in a new windowHyatt Regency Jacksonville
Scottish Inn Jacksonville Downtown

Scottish Inn Jacksonville Downtown

2.5 out of 5
2300 Phillips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
$44 nightly
The price is $50 total per night from Oct 25 to Oct 26
$50 total
Oct 25 - Oct 26
Total with taxes and fees
This motel doesn't skimp on freebies - guests receive free WiFi and free self parking. A garden, laundry facilities, and free newspapers are also on offer.
Opens in a new windowScottish Inn Jacksonville Downtown
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
9300 Baymeadows Road Jacksonville FL
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $117 total per night from Nov 5 to Nov 6
$117 total
Nov 5 - Nov 6
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 6 conference rooms, free WiFi in public areas, ...
Opens in a new windowEmbassy Suites by Hilton Jacksonville Baymeadows
The Villas of Amelia Island

The Villas of Amelia Island

4 out of 5
8 Amelia Village Circle, Amelia Island Fernandina Beach FL
Fully refundableReserve now, pay when you stay
$209 nightly
The price is $234 total per night from Nov 15 to Nov 16
$234 total
Nov 15 - Nov 16
Total with taxes and fees
This smoke-free vacation home features a golf course, a full-service spa, and 9 restaurants. Enjoy a day at the beach kayaking, or relax with beach cabanas. ...
Opens in a new windowThe Villas of Amelia Island
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

3 out of 5
1515 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $182 total per night from Nov 1 to Nov 2
$182 total
Nov 1 - Nov 2
Total with taxes and fees
This hotel features 2 outdoor pools, a 24-hour gym, and a restaurant. Unwind with a drink at one of the 2 bars/lounges and enjoy free perks like full breakfast ...
Opens in a new windowHampton Inn Jacksonville Beach/Oceanfront
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Isle of Palms South Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on Isle of Palms South area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near Isle of Palms South to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near Isle of Palms South are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent Isle of Palms South hotel reviews by fellow wanderers

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

4 out of 5
Posted less than an hour ago
Travelocity Verified Review
"walls between rooms are paper thin"
A verified traveler stayed at Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

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